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| Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway WA Freed-Pastor, H Mizuno, X Zhao, A Langerød, SH Moon, ... Cell 148 (1), 244-258, 2012 | 1004 | 2012 |
| p53 represses the mevalonate pathway to mediate tumor suppression SH Moon, CH Huang, SL Houlihan, K Regunath, WA Freed-Pastor, ... Cell 176 (3), 564-580. e19, 2019 | 432 | 2019 |
| Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment WL Hwang, KA Jagadeesh, JA Guo, HI Hoffman, P Yadollahpour, ... Nature genetics 54 (8), 1178-1191, 2022 | 362 | 2022 |
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| Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes JM Schenkel, RH Herbst, D Canner, A Li, M Hillman, SL Shanahan, ... Immunity 54 (10), 2338-2353. e6, 2021 | 279 | 2021 |
| The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer WA Freed-Pastor, LJ Lambert, ZA Ely, NB Pattada, A Bhutkar, G Eng, ... Cancer cell 39 (10), 1342-1360. e14, 2021 | 264 | 2021 |
| Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells NT Pfister, V Fomin, K Regunath, JY Zhou, W Zhou, L Silwal-Pandit, ... Genes & development 29 (12), 1298-1315, 2015 | 179 | 2015 |
| Quantitative analysis of the DNA methylation sensitivity of transcription factor complexes JF Kribelbauer, O Laptenko, S Chen, GD Martini, WA Freed-Pastor, ... Cell reports 19 (11), 2383-2395, 2017 | 138 | 2017 |
| Accurate and sensitive quantification of protein-DNA binding affinity C Rastogi, HT Rube, JF Kribelbauer, J Crocker, RE Loker, GD Martini, ... Proceedings of the National Academy of Sciences 115 (16), E3692-E3701, 2018 | 134 | 2018 |
| Deciphering the immunopeptidome in vivo reveals new tumour antigens AM Jaeger, LE Stopfer, R Ahn, EA Sanders, DA Sandel, WA Freed-Pastor, ... Nature 607 (7917), 149-155, 2022 | 106 | 2022 |
| Neoadjuvant chemotherapy is associated with altered immune cell infiltration and an anti-tumorigenic microenvironment in resected pancreatic cancer A Dias Costa, SA Väyrynen, A Chawla, J Zhang, JP Väyrynen, MC Lau, ... Clinical Cancer Research 28 (23), 5167-5179, 2022 | 64 | 2022 |
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| A prime editor mouse to model a broad spectrum of somatic mutations in vivo ZA Ely, N Mathey-Andrews, S Naranjo, SI Gould, KL Mercer, GA Newby, ... Nature biotechnology 42 (3), 424-436, 2024 | 51 | 2024 |
| Stability of checkpoint kinase 2 is regulated via phosphorylation at serine 456 EM Kass, J Ahn, T Tanaka, WA Freed-Pastor, S Keezer, C Prives Journal of Biological Chemistry 282 (41), 30311-30321, 2007 | 43 | 2007 |
| Single-nucleus and spatial transcriptomics of archival pancreatic cancer reveals multi-compartment reprogramming after neoadjuvant treatment WL Hwang, KA Jagadeesh, JA Guo, HI Hoffman, P Yadollahpour, ... BioRxiv, 2020.08. 25.267336, 2020 | 37 | 2020 |
| Pancreatic cancer–restricted cryptic antigens are targets for T cell recognition ZA Ely, ZJ Kulstad, G Gunaydin, S Addepalli, EK Verzani, M Casarrubios, ... Science 388 (6747), eadk3487, 2025 | 32 | 2025 |
| Targeting mutant p53 through the mevalonate pathway W Freed-Pastor, C Prives Nature cell biology 18 (11), 1122-1124, 2016 | 26 | 2016 |
| Use of Fatostatin for treating cancer having a p53 mutation WA Freed-Pastor, C Prives, T Osborne US Patent App. 14/373,147, 2014 | 24 | 2014 |
| Emerging role of targeted therapy in metastatic pancreatic adenocarcinoma BM Huffman, H Ellis, AC Jordan, WA Freed-Pastor, K Perez, DA Rubinson, ... Cancers 14 (24), 6223, 2022 | 23 | 2022 |
