| Chemical etiology of nucleic acid structure: the α-threofuranosyl-(3'→ 2') oligonucleotide system KU Schoning, P Scholz, S Guntha, X Wu, R Krishnamurthy, ... Science 290 (5495), 1347-1351, 2000 | 726 | 2000 |
| Ester‐mediated amide bond formation driven by wet–dry cycles: A possible path to polypeptides on the prebiotic earth JG Forsythe, SS Yu, I Mamajanov, MA Grover, R Krishnamurthy, ... Angewandte Chemie International Edition 54 (34), 9871-9875, 2015 | 404 | 2015 |
| The origin of RNA and “my grandfather’s axe” NV Hud, BJ Cafferty, R Krishnamurthy, LD Williams Chemistry & biology 20 (4), 466-474, 2013 | 269 | 2013 |
| Phosphorylation, oligomerization and self-assembly in water under potential prebiotic conditions C Gibard, S Bhowmik, M Karki, EK Kim, R Krishnamurthy Nature Chemistry 10 (2), 212-217, 2018 | 263 | 2018 |
| Chemistry of abiotic nucleotide synthesis M Yadav, R Kumar, R Krishnamurthy Chemical reviews 120 (11), 4766-4805, 2020 | 243 | 2020 |
| Pyranosyl‐RNA (‘p‐RNA’): Base‐pairing selectivity and potential to replicate. Preliminary communication S Pitsch, R Krishnamurthy, M Bolli, S Wendeborn, A Holzner, M Minton, ... Helvetica chimica acta 78 (7), 1621-1635, 1995 | 171 | 1995 |
| Spontaneous formation and base pairing of plausible prebiotic nucleotides in water BJ Cafferty, DM Fialho, J Khanam, R Krishnamurthy, NV Hud Nature communications 7 (1), 11328, 2016 | 159 | 2016 |
| Linked cycles of oxidative decarboxylation of glyoxylate as protometabolic analogs of the citric acid cycle G Springsteen, JR Yerabolu, J Nelson, CJ Rhea, R Krishnamurthy Nature communications 9 (1), 91, 2018 | 150 | 2018 |
| Chemical etiology of nucleic acid structure: Comparing pentopyranosyl-(2'→ 4') oligonucleotides with RNA M Beier, F Reck, T Wagner, R Krishnamurthy, A Eschenmoser Science 283 (5402), 699-703, 1999 | 146 | 1999 |
| A plausible simultaneous synthesis of amino acids and simple peptides on the primordial Earth ET Parker, M Zhou, AS Burton, DP Glavin, JP Dworkin, R Krishnamurthy, ... Angewandte Chemie 126 (31), 8270-8274, 2014 | 145 | 2014 |
| Role of pKa of Nucleobases in the Origins of Chemical Evolution R Krishnamurthy Accounts of chemical research 45 (12), 2035-2044, 2012 | 145 | 2012 |
| Selective incorporation of proteinaceous over nonproteinaceous cationic amino acids in model prebiotic oligomerization reactions M Frenkel-Pinter, JW Haynes, M C, AS Petrov, BT Burcar, ... Proceedings of the National Academy of Sciences 116 (33), 16338-16346, 2019 | 133 | 2019 |
| A plausible metal-free ancestral analogue of the Krebs cycle composed entirely of α-ketoacids RT Stubbs, M Yadav, R Krishnamurthy, G Springsteen Nature chemistry 12 (11), 1016-1022, 2020 | 128 | 2020 |
| Mapping the landscape of potentially primordial informational oligomers: oligodipeptides and oligodipeptoids tagged with triazines as recognition elements GK Mittapalli, KR Reddy, H Xiong, O Munoz, B Han, F De Riccardis, ... Angewandte Chemie 119 (14), 2522-2529, 2007 | 128 | 2007 |
| The α‐L‐Threofuranosyl‐(3′→2′)‐oligonucleotide System (‘TNA'): Synthesis and Pairing Properties KU Schöning, P Scholz, X Wu, S Guntha, G Delgado, R Krishnamurthy, ... Helvetica chimica acta 85 (12), 4111-4153, 2002 | 126 | 2002 |
| New codons for efficient production of unnatural proteins in a semisynthetic organism EC Fischer, K Hashimoto, Y Zhang, AW Feldman, VT Dien, ... Nature Chemical Biology 16 (5), 570-576, 2020 | 119 | 2020 |
| Regioselective alpha-Phosphorylation of Aldoses in Aqueous Solution Chemistry of alpha-aminonitriles, Part 29. Part 28: Ref. 1, Part 27: Ref. 2. This work was supported by the … R Krishnamurthy, S Guntha, A Eschenmoser Angewandte Chemie (International ed. in English) 39 (13), 2281-2285, 2000 | 119 | 2000 |
| Spontaneous prebiotic formation of a β-ribofuranoside that self-assembles with a complementary heterocycle MC Chen, BJ Cafferty, I Mamajanov, I Gállego, J Khanam, ... Journal of the American Chemical Society 136 (15), 5640-5646, 2014 | 112 | 2014 |
| Prebiotic phosphorylation of 2-thiouridine provides either nucleotides or DNA building blocks via photoreduction J Xu, NJ Green, C Gibard, R Krishnamurthy, JD Sutherland Nature chemistry 11 (5), 457-462, 2019 | 109 | 2019 |
| The role of sugar-backbone heterogeneity and chimeras in the simultaneous emergence of RNA and DNA S Bhowmik, R Krishnamurthy Nature chemistry 11 (11), 1009-1018, 2019 | 108 | 2019 |