| A kinase-cGAS cascade to synthesize a therapeutic STING activator JA McIntosh, Z Liu, BM Andresen, NS Marzijarani, JC Moore, NM Marshall, ... Nature 603 (7901), 439-444, 2022 | 117 | 2022 |
| Kilo-scale electrochemical oxidation of a thioether to a sulfone: a workflow for scaling up electrosynthesis C Bottecchia, D Lehnherr, F Lévesque, M Reibarkh, Y Ji, VL Rodrigues, ... Organic Process Research & Development 26 (8), 2423-2437, 2022 | 56 | 2022 |
| Electrochemical recycling of adenosine triphosphate in biocatalytic reaction cascades S Ruccolo, G Brito, M Christensen, T Itoh, K Mattern, K Stone, ... Journal of the American Chemical Society 144 (49), 22582-22588, 2022 | 39 | 2022 |
| Manufacturing process development for belzutifan, part 6: ensuring scalability for a deoxyfluorination reaction M Pirnot, K Stone, TJ Wright, DJ Lamberto, J Schoell, Y Lam, K Zawatzky, ... Organic Process Research & Development 26 (3), 551-559, 2021 | 34 | 2021 |
| Development of a Robust Manufacturing Route for Molnupiravir, an Antiviral for the Treatment of COVID-19 PS Fier, Y Xu, M Poirier, G Brito, M Zheng, R Bade, E Sirota, K Stone, ... Organic Process Research & Development 25 (12), 2806-2815, 2021 | 30 | 2021 |
| Manufacturing process development for belzutifan, part 4: nitrogen flow criticality for transfer hydrogenation control N Salehi Marzijarani, AJ Fine, SM Dalby, R Gangam, S Poudyal, T Behre, ... Organic Process Research & Development 26 (3), 533-542, 2021 | 27 | 2021 |
| Constrained version of the dynamic response surface methodology for modeling pharmaceutical reactions Y Dong, C Georgakis, J Mustakis, JM Hawkins, L Han, K Wang, ... Industrial & Engineering Chemistry Research 58 (30), 13611-13621, 2019 | 24 | 2019 |
| Multigram Electrochemical Hofmann Rearrangement Using a Spinning Three-Dimensional Anode BK Malviya, C Bottecchia, K Stone, D Lehnherr, F Lévesque, CO Kappe, ... Organic Process Research & Development 27 (11), 2183-2191, 2023 | 22 | 2023 |
| KA Canada, PG Bulger, BD Sherry, MD Truppo, RT Ruck, L.-C. Campeau, DJ Bennett, GR Humphrey, KR Campos, ML Maddess JA McIntosh, Z Liu, BM Andresen, NS Marzijarani, JC Moore, NM Marshall, ... Nature 603, 439-444, 2022 | 20 | 2022 |
| Canada, KA; Bulger, PG; Sherry, BD; Truppo, M. D.; Ruck, RT; Campeau, L.-C.; Bennett, DJ; Humphrey, GR; Campos, KR; Maddess, ML A Kinase-cGAS Cascade to Synthesize a … JA McIntosh, Z Liu, BM Andresen, NS Marzijarani, JC Moore, NM Marshall, ... Nature 603 (7901), 439-444, 2022 | 18 | 2022 |
| Stoichiometry identification of pharmaceutical reactions using the constrained dynamic response surface methodology Y Dong, C Georgakis, J Mustakis, JM Hawkins, L Han, K Wang, ... AIChE Journal 65 (11), e16726, 2019 | 17 | 2019 |
| Development of a green and sustainable manufacturing process for gefapixant citrate (MK-7264) Part 4: formylation–cyclization as a flow–batch process leads to significant … DAL Otte, K Basu, L Jellett, M Whittington, G Spencer, M Burris, ... Organic Process Research & Development 24 (11), 2478-2490, 2020 | 16 | 2020 |
| Polymorphs, particle size, and a pandemic: development of a scalable crystallization process for molnupiravir, an antiviral for the treatment of COVID-19 R Bade, JR Bothe, E Sirota, APJ Brunskill, JA Newman, Y Zhang, M Tan, ... Organic Process Research & Development 27 (11), 2100-2110, 2023 | 4 | 2023 |
| Characterization of Propionyl Phosphate Hydrolysis Kinetics by Data-Rich Experiments and In-Line Process Analytical Technology C Yang, H Feng, K Stone Organic Process Research & Development 25 (3), 507-515, 2021 | 4 | 2021 |
| Accelerated Process Design and Optimization for a Small Molecule COVID-19 Therapeutic M Zheng, R Bade, K Stone, P Fier, G Brito, S Castro 2021 AIChE Annual Meeting, 2021 | | 2021 |
| Optimal Time Sampling Strategy in Pharmaceutical Reactions for the Estimation of Accurate DRSM Models Y Dong, C Georgakis, J Mustakis, K Wang, J Hawkins, JP McMullen, ... 2019 AIChE Annual Meeting, 2019 | | 2019 |
| Reaction Kinetic Modeling and Process Optimization of Multi-Enzyme Biocatalytic Cascade Syntheses K Stone, JP McMullen, ST Grosser, J Forstater, G Hughes, A Fryszkowska, ... 2019 AIChE Annual Meeting, 2019 | | 2019 |
| Model-Based Design of Experiments for Pharmaceutical Reaction Development K Stone, JP McMullen, D Willard 2018 AIChE Annual Meeting, 2018 | | 2018 |
| Developing Process Control Strategies for Drug Product Manufacture D Hebrault, K Stone 2018 AIChE Annual Meeting, 2018 | | 2018 |
| Process Fingerprinting Tools in the Development of an Alkylation Reaction K Stone, B Wyvratt, E Adachi, M Mohan, JP McMullen 2018 AIChE Annual Meeting, 2018 | | 2018 |
