| In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy CE Nelson, CH Hakim, DG Ousterout, PI Thakore, EA Moreb, RMC Rivera, ... Science 351 (6271), 403-407, 2016 | 1469 | 2016 |
| Ex Vivo Red Blood Cell Hemolysis Assay for the Evaluation of pH-responsive Endosomolytic Agents for Cytosolic Delivery of Biomacromolecular Drugs. BC Evans, CE Nelson, SS Yu, KR Beavers, AJ Kim, H Li, HM Nelson, ... Journal of visualized experiments: JoVE, 2012 | 584 | 2012 |
| Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy CE Nelson, Y Wu, MP Gemberling, ML Oliver, MA Waller, JD Bohning, ... Nature medicine 25 (3), 427-432, 2019 | 496 | 2019 |
| Balancing Cationic and Hydrophobic Content of PEGylated siRNA Polyplexes Enhances Endosome Escape, Stability, Blood Circulation Time, and Bioactivity in Vivo CE Nelson, JR Kintzing, A Hanna, JM Shannon, MK Gupta, CL Duvall ACS nano 7 (10), 8870-8880, 2013 | 374 | 2013 |
| ROS-responsive microspheres for on demand antioxidant therapy in a model of diabetic peripheral arterial disease KM Poole, CE Nelson, RV Joshi, JR Martin, MK Gupta, SC Haws, ... Biomaterials 41, 166-175, 2015 | 231 | 2015 |
| Poly (PS-b-DMA) micelles for reactive oxygen species triggered drug release MK Gupta, TA Meyer, CE Nelson, CL Duvall Journal of Controlled Release 162 (3), 591-598, 2012 | 217 | 2012 |
| RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors PI Thakore, JB Kwon, CE Nelson, DC Rouse, MP Gemberling, ML Oliver, ... Nature communications 9 (1), 1674, 2018 | 201 | 2018 |
| Tunable Delivery of siRNA from a Biodegradable Scaffold to Promote Angiogenesis In Vivo CE Nelson, AJ Kim, EJ Adolph, MK Gupta, F Yu, KM Hocking, ... Advanced Materials 26 (4), 607-614, 2014 | 190 | 2014 |
| Tuning PEGylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers M Miteva, KC Kirkbride, KV Kilchrist, TA Werfel, H Li, CE Nelson, ... Biomaterials 38, 97-107, 2015 | 183 | 2015 |
| Macrophage-Specific RNA Interference Targeting via “Click”, Mannosylated Polymeric Micelles SS Yu, CM Lau, WJ Barham, HM Onishko, CE Nelson, H Li, CA Smith, ... Molecular pharmaceutics 10 (3), 975-987, 2013 | 176 | 2013 |
| Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models CH Hakim, SRP Kumar, DO Pérez-López, NB Wasala, D Zhang, Y Yue, ... Nature communications 12 (1), 6769, 2021 | 166 | 2021 |
| Engineering delivery vehicles for genome editing CE Nelson, CA Gersbach Annual review of chemical and biomolecular engineering 7 (1), 637-662, 2016 | 149 | 2016 |
| Matrix Metalloproteinase Responsive, Proximity‐Activated Polymeric Nanoparticles for siRNA Delivery H Li, SS Yu, M Miteva, CE Nelson, T Werfel, TD Giorgio, CL Duvall Advanced Functional Materials 23 (24), 3040-3052, 2013 | 137 | 2013 |
| AAV CRISPR editing rescues cardiac and muscle function for 18 months in dystrophic mice CH Hakim, NB Wasala, CE Nelson, LP Wasala, Y Yue, JA Louderman, ... JCI insight 3 (23), e124297, 2018 | 115 | 2018 |
| MiRNA inhibition in tissue engineering and regenerative medicine KR Beavers, CE Nelson, CL Duvall Advanced drug delivery reviews 88, 123-137, 2015 | 111 | 2015 |
| Targeted transcriptional modulation with type I CRISPR–Cas systems in human cells A Pickar-Oliver, JB Black, MM Lewis, KJ Mutchnick, TS Klann, KA Gilcrest, ... Nature biotechnology 37 (12), 1493-1501, 2019 | 108 | 2019 |
| Technologies for controlled, local delivery of siRNA SM Sarett, CE Nelson, CL Duvall Journal of Controlled Release 218, 94-113, 2015 | 102 | 2015 |
| Local delivery of PHD2 siRNA from ROS-degradable scaffolds to promote diabetic wound healing JR Martin, CE Nelson, MK Gupta, F Yu, SM Sarett, KM Hocking, ... Advanced healthcare materials 5 (21), 2751, 2016 | 101 | 2016 |
| Sustained local delivery of siRNA from an injectable scaffold CE Nelson, MK Gupta, EJ Adolph, JM Shannon, SA Guelcher, CL Duvall Biomaterials 33 (4), 1154-1161, 2012 | 95 | 2012 |
| Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma J Huang, M Chen, MJ Whitley, HC Kuo, ES Xu, A Walens, YM Mowery, ... Nature communications 8 (1), 15999, 2017 | 87 | 2017 |
Mukesh Kumar GuptaResearch Associate Professor of Biomedical EngineeringVerified email at vanderbilt.edu
