| Synaptic vesicle glycoprotein 2A ligands in the treatment of epilepsy and beyond W Löscher, M Gillard, ZA Sands, RM Kaminski, H Klitgaard CNS drugs 30 (11), 1055-1077, 2016 | 212 | 2016 |
| An aqueous H+ permeation pathway in the voltage-gated proton channel Hv1 IS Ramsey, Y Mokrab, I Carvacho, ZA Sands, MSP Sansom, DE Clapham Nature structural & molecular biology 17 (7), 869-875, 2010 | 191 | 2010 |
| Design, Synthesis, and Biophysical and Biological Evaluation of a Series of Pyrrolobenzodiazepine−Poly(N-methylpyrrole) Conjugates G Wells, CRH Martin, PW Howard, ZA Sands, CA Laughton, A Tiberghien, ... Journal of medicinal chemistry 49 (18), 5442-5461, 2006 | 186 | 2006 |
| Binding mode and structure–activity relationships around direct inhibitors of the Nrf2–Keap1 complex E Jnoff, C Albrecht, JJ Barker, O Barker, E Beaumont, S Bromidge, ... ChemMedChem 9 (4), 699-705, 2014 | 175 | 2014 |
| Crystal structure of the adenosine A2A receptor bound to an antagonist reveals a potential allosteric pocket B Sun, P Bachhawat, MLH Chu, M Wood, T Ceska, ZA Sands, J Mercier, ... Proceedings of the National Academy of Sciences 114 (8), 2066-2071, 2017 | 158 | 2017 |
| How does a voltage sensor interact with a lipid bilayer? Simulations of a potassium channel domain ZA Sands, MSP Sansom Structure 15 (2), 235-244, 2007 | 118 | 2007 |
| Molecular dynamics simulations of duplex stretching reveal the importance of entropy in determining the biomechanical properties of DNA SA Harris, ZA Sands, CA Laughton Biophysical journal 88 (3), 1684-1691, 2005 | 117 | 2005 |
| Voltage-gated ion channels Z Sands, A Grottesi, MSP Sansom Current Biology 15 (2), R44-R47, 2005 | 103 | 2005 |
| GRIN2B gain of function mutations are sensitive to radiprodil, a negative allosteric modulator of GluN2B-containing NMDA receptors B Mullier, C Wolff, ZA Sands, P Ghisdal, P Muglia, RM Kaminski, ... Neuropharmacology 123, 322-331, 2017 | 74 | 2017 |
| Insight into the mechanism of inactivation and pH sensitivity in potassium channels from molecular dynamics simulations PJ Stansfeld, A Grottesi, ZA Sands, MSP Sansom, P Gedeck, M Gosling, ... Biochemistry 47 (28), 7414-7422, 2008 | 72 | 2008 |
| Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist B Sun, D Feng, MLH Chu, I Fish, S Lovera, ZA Sands, S Kelm, A Valade, ... Nature communications 12 (1), 3305, 2021 | 67 | 2021 |
| Molecular simulations and lipid–protein interactions: potassium channels and other membrane proteins MSP Sansom, PJ Bond, SS Deol, A Grottesi, S Haider, ZA Sands Biochemical Society Transactions 33 (5), 916-920, 2005 | 54 | 2005 |
| Detergent-free extraction of a functional low-expressing GPCR from a human cell line JFB Juarez, JC Muñoz-García, RI Dos Reis, A Henry, D McMillan, M Kriek, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1862 (3), 183152, 2020 | 53 | 2020 |
| Alchembed: a computational method for incorporating multiple proteins into complex lipid geometries E Jefferys, ZA Sands, J Shi, MSP Sansom, PW Fowler Journal of Chemical Theory and Computation 11 (6), 2743-2754, 2015 | 48 | 2015 |
| Vstx1, a modifier of Kv channel gating, localizes to the interfacial region of lipid bilayers D Bemporad, ZA Sands, CL Wee, A Grottesi, MSP Sansom Biochemistry 45 (39), 11844-11855, 2006 | 48 | 2006 |
| A numbering system for MFS transporter proteins J Lee, ZA Sands, PC Biggin Frontiers in molecular biosciences 3, 21, 2016 | 46 | 2016 |
| Accelerating GPCR drug discovery with conformation-stabilizing VHHs T Laeremans, ZA Sands, P Claes, A De Blieck, S De Cesco, S Triest, ... Frontiers in molecular biosciences 9, 863099, 2022 | 45 | 2022 |
| SGTx1, a Kv channel gating-modifier toxin, binds to the interfacial region of lipid bilayers CL Wee, D Bemporad, ZA Sands, D Gavaghan, MSP Sansom Biophysical journal 92 (1), L07-L09, 2007 | 45 | 2007 |
| The intrinsic flexibility of the Kv voltage sensor and its implications for channel gating ZA Sands, A Grottesi, MSP Sansom Biophysical journal 90 (5), 1598-1606, 2006 | 42 | 2006 |
| Exploring the interaction of SV2A with racetams using homology modelling, molecular dynamics and site-directed mutagenesis J Lee, V Daniels, ZA Sands, F Lebon, J Shi, PC Biggin PloS one 10 (2), e0116589, 2015 | 40 | 2015 |
