| The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and γ radiation: duration of JNK activation may determine cell death and proliferation YR Chen, X Wang, D Templeton, RJ Davis, TH Tan Journal of Biological Chemistry 271 (50), 31929-31936, 1996 | 1137 | 1996 |
| High frequency of epidermal growth factor receptor mutations with complex patterns in non–small cell lung cancers related to gefitinib responsiveness in Taiwan SF Huang, HP Liu, LH Li, YC Ku, YN Fu, HY Tsai, YT Chen, YF Lin, ... Clinical Cancer Research 10 (24), 8195-8203, 2004 | 733 | 2004 |
| Persistent Activation of c-Jun N-terminal Kinase 1 (JNK1) in γ Radiation-induced Apoptosis (∗) YR Chen, CF Meyer, TH Tan Journal of Biological Chemistry 271 (2), 631-634, 1996 | 594 | 1996 |
| Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin YR Chen, TH Tan Oncogene 17 (2), 173-178, 1998 | 520 | 1998 |
| The c-Jun N-terminal kinase pathway and apoptotic signaling YR Chen, TH Tan International journal of oncology 16 (4), 651-713, 2000 | 324 | 2000 |
| Molecular mechanisms of c-Jun N-terminal kinase-mediated apoptosis induced by anticarcinogenic isothiocyanates YR Chen, W Wang, ANT Kong, TH Tan Journal of Biological Chemistry 273 (3), 1769-1775, 1998 | 316 | 1998 |
| Distinctive activation patterns in constitutively active and gefitinib-sensitive EGFR mutants YR Chen, YN Fu, CH Lin, ST Yang, SF Hu, YT Chen, SF Tsai, SF Huang Oncogene 25 (8), 1205-1215, 2006 | 172 | 2006 |
| Comparison of IHC, FISH and RT-PCR Methods for Detection of ALK Rearrangements in 312 Non-Small Cell Lung Cancer Patients in Taiwan YC Wu, IC Chang, CL Wang, TD Chen, YT Chen, HP Liu, Y Chu, YT Chiu, ... PLoS One 8 (8), e70839, 2013 | 126 | 2013 |
| Down-regulation of the c-Jun N-terminal kinase (JNK) phosphatase M3/6 and activation of JNK by hydrogen peroxide and pyrrolidine dithiocarbamate YR Chen, A Shrivastava, TH Tan Oncogene 20 (3), 367-374, 2001 | 126 | 2001 |
| Design and Synthesis of Tetrahydropyridothieno[2,3-d]pyrimidine Scaffold Based Epidermal Growth Factor Receptor (EGFR) Kinase Inhibitors: The Role of Side … CH Wu, MS Coumar, CY Chu, WH Lin, YR Chen, CT Chen, HY Shiao, ... Journal of medicinal chemistry 53 (20), 7316-7326, 2010 | 123 | 2010 |
| c-Jun N-Terminal Kinase Mediates Apoptotic Signaling Induced byN-(4-Hydroxyphenyl) retinamide YR Chen, G Zhou, TH Tan Molecular pharmacology 56 (6), 1271-1279, 1999 | 114 | 1999 |
| Reversed mutation rates of KRAS and EGFR genes in adenocarcinoma of the lung in Taiwan and their implications CC Wu, HY Hsu, HP Liu, JWC Chang, YT Chen, WY Hsieh, JJ Hsieh, ... Cancer: Interdisciplinary International Journal of the American Cancer …, 2008 | 109 | 2008 |
| Phenylethyl isothiocyanate induces apoptotic signaling via suppressing phosphatase activity against c-Jun N-terminal kinase YR Chen, J Han, R Kori, ANT Kong, TH Tan Journal of Biological Chemistry 277 (42), 39334-39342, 2002 | 106 | 2002 |
| Caspase-mediated cleavage and functional changes of hematopoietic progenitor kinase 1 (HPK1) YR Chen, CF Meyer, B Ahmed, Z Yao, TH Tan Oncogene 18 (51), 7370-7377, 1999 | 93 | 1999 |
| EGFR over-expression in non-small cell lung cancers harboring EGFR mutations is associated with marked down-regulation of CD82 CH Yang, HC Chou, YN Fu, CL Yeh, HW Cheng, IC Chang, KJ Liu, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (7 …, 2015 | 76 | 2015 |
| The SH3 domain-containing adaptor HIP-55 mediates c-Jun N-terminal kinase activation in T cell receptor signaling J Han, R Kori, JW Shui, YR Chen, Z Yao, TH Tan Journal of Biological Chemistry 278 (52), 52195-52202, 2003 | 70 | 2003 |
| JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration JP Li, YN Fu, YR Chen, TH Tan Journal of biological chemistry 285 (8), 5472-5478, 2010 | 68 | 2010 |
| Vaccinia H1-related phosphatase is a phosphatase of ErbB receptors and is down-regulated in non-small cell lung cancer JY Wang, CL Yeh, HC Chou, CH Yang, YN Fu, YT Chen, HW Cheng, ... Journal of Biological Chemistry 286 (12), 10177-10184, 2011 | 63 | 2011 |
| Increased epidermal growth factor receptor (EGFR) gene copy number is strongly associated with EGFR mutations and adenocarcinoma in non-small cell lung cancers: a chromogenic … JWC Chang, HP Liu, MH Hsieh, YF Fang, MS Hsieh, JJ Hsieh, YT Chiu, ... Lung Cancer 61 (3), 328-339, 2008 | 61 | 2008 |
| Prognostic implications of epidermal growth factor receptor and KRAS gene mutations and epidermal growth factor receptor gene copy numbers in patients with surgically … HP Liu, HDI Wu, JWC Chang, YC Wu, HY Yang, YT Chen, WY Hsieh, ... Journal of Thoracic Oncology 5 (8), 1175-1184, 2010 | 58 | 2010 |
