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Edward A. FitzGerald
Edward A. FitzGerald
Industrial Marie Curie Fellow, Uppsala University & Beactica Therapeutics
Verified email at kemi.uu.se
Title
Cited by
Cited by
Year
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
TE Park, N Mustafaoglu, A Herland, R Hasselkus, R Mannix, ...
Nature communications 10 (1), 2621, 2019
6462019
Distinct contributions of astrocytes and pericytes to neuroinflammation identified in a 3D human blood-brain barrier on a chip
A Herland, AD Van Der Meer, EA FitzGerald, TE Park, JJF Sleeboom, ...
PloS one 11 (3), e0150360, 2016
5162016
A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells
BM Maoz, A Herland, EA FitzGerald, T Grevesse, C Vidoudez, ...
Nature biotechnology 36 (9), 865-874, 2018
4672018
Robotic fluidic coupling and interrogation of multiple vascularized organ chips
R Novak, M Ingram, S Marquez, D Das, A Delahanty, A Herland, BM Maoz, ...
Nature biomedical engineering 4 (4), 407-420, 2020
4192020
The quest for permanence: The symbolism of Wordsworth, Shelley, and Keats
D Perkins
Harvard University Press, 1959
2981959
Organs-on-Chips with combined multi-electrode array and transepithelial electrical resistance measurement capabilities
BM Maoz, A Herland, OYF Henry, WD Leineweber, M Yadid, J Doyle, ...
Lab on a Chip 17 (13), 2294-2302, 2017
2882017
The epidemiology of injuries in Australian professional rugby union 2014 super rugby competition
T Whitehouse, R Orr, E Fitzgerald, S Harries, CP McLellan
Orthopaedic journal of sports medicine 4 (3), 2325967116634075, 2016
752016
A robotic platform for fluidically-linked human body-on-chips experimentation
R Novak, M Ingram, S Clauson, D Das, A Delahanty, A Herland, BM Maoz, ...
Nature biomedical engineering 4 (4), 407, 2020
272020
Proteomic and metabolomic characterization of human neurovascular unit cells in response to methamphetamine
A Herland, BM Maoz, EA FitzGerald, T Grevesse, C Vidoudez, SP Sheehy, ...
Advanced biosystems 4 (9), 1900230, 2020
212020
Bilateral primary renal lymphoma
AW O Sullivan, G Lee, E Fitzgerald, GC O Sullivan
Irish journal of medical science 172 (1), 44-45, 2003
172003
Multiplexed experimental strategies for fragment library screening against challenging drug targets using SPR biosensors
EA FitzGerald, D Vagrys, G Opassi, HF Klein, DJ Hamilton, VO Talibov, ...
SLAS Discovery 29 (1), 40-51, 2024
152024
Discovery of an allosteric ligand binding site in SMYD3 lysine methyltransferase
VO Talibov, E Fabini, EA FitzGerald, D Tedesco, D Cederfelt, MJ Talu, ...
ChemBioChem 22 (9), 1597-1608, 2021
152021
Hypoxia-enhanced blood–brain barrier chip recapitulates human barrier function and shuttling of drugs and antibodies. Nat Commun. 2019; 10 (1): 2621
TE Park, N Mustafaoglu, A Herland, R Hasselkus, R Mannix, ...
122019
Discovery of fragments inducing conformational effects in dynamic proteins using a second-harmonic generation biosensor
EA FitzGerald, MT Butko, P Boronat, D Cederfelt, M Abramsson, ...
Rsc Advances 11 (13), 7527-7537, 2021
112021
Identification of fragments targeting SMYD3 using highly sensitive kinetic and multiplexed biosensor-based screening
EA FitzGerald, D Cederfelt, BA Lund, NEM Myers, H Zhang, D Dobritzsch, ...
RSC Medicinal Chemistry 15 (6), 1982-1990, 2024
102024
Binding‐Site Purification of Actives (B‐SPA) Enables Efficient Large‐Scale Progression of Fragment Hits by Combining Multi‐Step Array Synthesis With HT Crystallography
H Grosjean, A Aimon, S Hassell‐Hart, W Thompson, L Koekemoer, ...
Angewandte Chemie International Edition 64 (16), e202424373, 2025
82025
High-throughput crystallography for rapid fragment growth from crude arrays by low-cost robotics
H Grosjean, A Aimon, S Hassell-Hart, W Thompson, L Koekemoer, ...
52023
Efficient large-scale exploration of fragment hit progression by exploiting binding-site purification of actives (B-SPA) through combining multi-step array synthesis and HT …
H Grosjean, A Aimon, S Hassell-Hart, W Thompson, L Koekemoer, ...
ChemRxiv, 2024
22024
Blood-brain barrier endothelial cells derived from pluripotent stem cells for blood-brain barrier models
TE Park, A Herland, EA FITZGERALD, DE Ingber
US Patent 11,371,022, 2022
22022
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function, drug penetration, and antibody shuttling properties
TE Park, N Mustafaoglu, A Herland, R Hasselkus, R Mannix, ...
2
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