| TGF-β induces apoptosis through Smad-mediated expression of DAP-kinase CW Jang, CH Chen, CC Chen, J Chen, YH Su, RH Chen Nature cell biology 4 (1), 51-58, 2002 | 567 | 2002 |
| Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12 X Wang, YC Wu, VA Fadok, MC Lee, K Gengyo-Ando, LC Cheng, ... Science 302 (5650), 1563-1566, 2003 | 255 | 2003 |
| SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis JR Lin, MK Zeman, JY Chen, MC Yee, KA Cimprich Molecular cell 42 (2), 237-249, 2011 | 238 | 2011 |
| Cyclic immunofluorescence (CycIF), a highly multiplexed method for single‐cell imaging JR Lin, M Fallahi‐Sichani, JY Chen, PK Sorger Current protocols in chemical biology 8 (4), 251-264, 2016 | 234 | 2016 |
| Fluctuations in p53 signaling allow escape from cell-cycle arrest J Reyes, JY Chen, J Stewart-Ornstein, KW Karhohs, CS Mock, G Lahav Molecular cell 71 (4), 581-591. e5, 2018 | 171 | 2018 |
| Dosage of Dyrk1a shifts cells within a p21-cyclin D1 signaling map to control the decision to enter the cell cycle JY Chen, JR Lin, FC Tsai, T Meyer Molecular cell 52 (1), 87-100, 2013 | 167 | 2013 |
| A two-dimensional ERK-AKT signaling code for an NGF-triggered cell-fate decision JY Chen, JR Lin, KA Cimprich, T Meyer Molecular cell 45 (2), 196-209, 2012 | 162 | 2012 |
| Receptor-driven ERK pulses reconfigure MAPK signaling and enable persistence of drug-adapted BRAF-mutant melanoma cells L Gerosa, C Chidley, F Fröhlich, G Sanchez, SK Lim, J Muhlich, JY Chen, ... Cell systems 11 (5), 478-494. e9, 2020 | 122 | 2020 |
| Defective axonal transport of Rab7 GTPase results in dysregulated trophic signaling K Zhang, RFB Kenan, Y Osakada, W Xu, RS Sinit, L Chen, X Zhao, ... Journal of Neuroscience 33 (17), 7451-7462, 2013 | 114 | 2013 |
| A probabilistic approach to joint cell tracking and segmentation in high-throughput microscopy videos A Arbelle, J Reyes, JY Chen, G Lahav, TR Raviv Medical image analysis 47, 140-152, 2018 | 39 | 2018 |
| Inhibition of haspin kinase promotes cell-intrinsic and extrinsic antitumor activity JC Melms, S Vallabhaneni, CE Mills, C Yapp, JY Chen, E Morelli, ... Cancer research 80 (4), 798-810, 2020 | 34 | 2020 |
| Torin2 exploits replication and checkpoint vulnerabilities to cause death of PI3K-activated triple-negative breast cancer cells SS Chopra, A Jenney, A Palmer, M Niepel, M Chung, C Mills, ... Cell systems 10 (1), 66-81. e11, 2020 | 34 | 2020 |
| Skin immune-mesenchymal interplay within tertiarylymphoid structures promotes autoimmunepathogenesis in hidradenitis suppurativa WW Yu, JNP Barrett, J Tong, MJ Lin, M Marohn, JC Devlin, A Herrera, ... Immunity 57 (12), 2827-2842. e5, 2024 | 24 | 2024 |
| Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction JY Chen, C Hug, J Reyes, C Tian, L Gerosa, F Fröhlich, B Ponsioen, ... Cell reports 42 (3), 2023 | 22 | 2023 |
| Fully unsupervised symmetry-based mitosis detection in time-lapse cell microscopy T Gilad, J Reyes, JY Chen, G Lahav, T Riklin Raviv Bioinformatics 35 (15), 2644-2653, 2019 | 17 | 2019 |
| Reciprocal antagonism of PIN1-APC/CCDH1 governs mitotic protein stability and cell cycle entry S Ke, F Dang, L Wang, JY Chen, MT Naik, W Li, A Thavamani, N Kim, ... Nature communications 15 (1), 3220, 2024 | 12 | 2024 |
| C. elegans EIF-3. K promotes programmed cell death through CED-3 caspase CY Huang, JY Chen, SC Wu, CH Tan, RY Tzeng, PJ Lu, YF Wu, RH Chen, ... PLoS One 7 (5), e36584, 2012 | 11 | 2012 |
| Fluctuations in p53 signaling allow escape from cell-cycle arrest J Reyes, JY Chen, J Stewart-Ornstein, KW Karhohs, CS Mock, G Lahav Molecular cell 73 (6), 1306, 2019 | 10 | 2019 |
| Sporadic ERK pulses drive non-genetic resistance in drug-adapted BRAFV600E melanoma cells L Gerosa, C Chidley, F Froehlich, G Sanchez, SK Lim, J Muhlich, JY Chen, ... BioRxiv, 762294, 2019 | 8 | 2019 |
| Reciprocal inhibition of PIN1 and APC/CCDH1 controls timely G1/S transition and creates therapeutic vulnerability S Ke, F Dang, L Wang, JY Chen, MT Naik, A Thavamani, Y Liu, W Li, ... Research Square, rs. 3. rs-2447544, 2023 | 4 | 2023 |
Jia-Ren LinHarvard Medical School; Stanford University; National Taiwan UniversityVerified email at hms.harvard.edu
