| Identification of ubiquitin ligases required for skeletal muscle atrophy SC Bodine, E Latres, S Baumhueter, VKM Lai, L Nunez, BA Clarke, ... Science 294 (5547), 1704-1708, 2001 | 4317 | 2001 |
| Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo SC Bodine, TN Stitt, M Gonzalez, WO Kline, GL Stover, R Bauerlein, ... Nature cell biology 3 (11), 1014-1019, 2001 | 3479 | 2001 |
| The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors TN Stitt, D Drujan, BA Clarke, F Panaro, Y Timofeyva, WO Kline, ... Molecular cell 14 (3), 395-403, 2004 | 2392 | 2004 |
| Mediation of IGF-1-induced skeletal myotube hypertrophy by PI (3) K/Akt/mTOR and PI (3) K/Akt/GSK3 pathways C Rommel, SC Bodine, BA Clarke, R Rossman, L Nunez, TN Stitt, ... Nature cell biology 3 (11), 1009-1013, 2001 | 2008 | 2001 |
| IKKβ/NF-κB activation causes severe muscle wasting in mice D Cai, JD Frantz, NE Tawa, PA Melendez, BC Oh, HGW Lidov, ... Cell 119 (2), 285-298, 2004 | 1710 | 2004 |
| Skeletal muscle hypertrophy and atrophy signaling pathways DJ Glass The international journal of biochemistry & cell biology 37 (10), 1974-1984, 2005 | 1481 | 2005 |
| Cancer cachexia: mediators, signaling, and metabolic pathways KCH Fearon, DJ Glass, DC Guttridge Cell metabolism 16 (2), 153-166, 2012 | 1468 | 2012 |
| The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo TM DeChiara, DC Bowen, DM Valenzuela, MV Simmons, WT Poueymirou, ... Cell 85 (4), 501-512, 1996 | 1144 | 1996 |
| trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor SP Squinto, TN Stitt, TH Aldrich, S Davis, SM Blanco, C RadzieJewski, ... Cell 65 (5), 885-893, 1991 | 1031 | 1991 |
| Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt C Rommel, BA Clarke, S Zimmermann, L Nunez, R Rossman, K Reid, ... Science 286 (5445), 1738-1741, 1999 | 1004 | 1999 |
| Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size AU Trendelenburg, A Meyer, D Rohner, J Boyle, S Hatakeyama, DJ Glass American Journal of Physiology-Cell Physiology 296 (6), C1258-C1270, 2009 | 973 | 2009 |
| Signalling pathways that mediate skeletal muscle hypertrophy and atrophy DJ Glass Nature cell biology 5 (2), 87-90, 2003 | 945 | 2003 |
| The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases TN Stitt, G Conn, M Goret, C Lai, J Bruno, C Radzlejewski, K Mattsson, ... Cell 80 (4), 661-670, 1995 | 936 | 1995 |
| Agrin acts via a MuSK receptor complex DJ Glass, DC Bowen, TN Stitt, C Radziejewski, JA Bruno, TE Ryan, ... Cell 85 (4), 513-523, 1996 | 880 | 1996 |
| The E3 Ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle BA Clarke, D Drujan, MS Willis, LO Murphy, RA Corpina, E Burova, ... Cell metabolism 6 (5), 376-385, 2007 | 847 | 2007 |
| mTOR inhibition improves immune function in the elderly JB Mannick, G Del Giudice, M Lattanzi, NM Valiante, J Praestgaard, ... Science translational medicine 6 (268), 268ra179-268ra179, 2014 | 817 | 2014 |
| During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation S Cohen, JJ Brault, SP Gygi, DJ Glass, DM Valenzuela, C Gartner, ... Journal of Cell Biology 185 (6), 1083-1095, 2009 | 764 | 2009 |
| Signaling pathways controlling skeletal muscle mass MA Egerman, DJ Glass Critical reviews in biochemistry and molecular biology 49 (1), 59-68, 2014 | 680 | 2014 |
| An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors A Shrivastava, C Radziejewski, E Campbell, L Kovac, M McGlynn, ... Molecular cell 1 (1), 25-34, 1997 | 665 | 1997 |
| Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway E Latres, AR Amini, AA Amini, J Griffiths, FJ Martin, Y Wei, HC Lin, ... Journal of Biological Chemistry 280 (4), 2737-2744, 2005 | 664 | 2005 |
Jennifer L. BrogdonNovartisVerified email at novartis.com
