| Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein MJ Gale Jr, MJ Korth, NM Tang, SL Tan, DA Hopkins, TE Dever, ... Virology 230 (2), 217-227, 1997 | 1080 | 1997 |
| Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation M Gale Jr, CM Blakely, B Kwieciszewski, SL Tan, M Dossett, NM Tang, ... Molecular and cellular biology 18 (9), 5208-5218, 1998 | 817 | 1998 |
| Arbidol as a broad-spectrum antiviral: an update J Blaising, SJ Polyak, EI Pécheur Antiviral research 107, 84-94, 2014 | 643 | 2014 |
| Arbidol: a broad-spectrum antiviral compound that blocks viral fusion YS Boriskin, IA Leneva, EI Pecheur, SJ Polyak Current medicinal chemistry 15 (10), 997-1005, 2008 | 575 | 2008 |
| Hepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response SJ Polyak, KSA Khabar, DM Paschal, HJ Ezelle, G Duverlie, GN Barber, ... Journal of virology 75 (13), 6095-6106, 2001 | 457 | 2001 |
| Identification of hepatoprotective flavonolignans from silymarin SJ Polyak, C Morishima, V Lohmann, S Pal, DYW Lee, Y Liu, TN Graf, ... Proceedings of the national academy of sciences 107 (13), 5995-5999, 2010 | 442 | 2010 |
| Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins ST Shi, SJ Polyak, H Tu, DR Taylor, DR Gretch, MMC Lai Virology 292 (2), 198-210, 2002 | 426 | 2002 |
| Inhibition of T-cell inflammatory cytokines, hepatocyte NF-κB signaling, and HCV infection by standardized silymarin SJ Polyak, C Morishima, MC Shuhart, CC Wang, Y Liu, DYW Lee Gastroenterology 132 (5), 1925-1936, 2007 | 329 | 2007 |
| Multiple effects of silymarin on the hepatitis C virus lifecycle J Wagoner, A Negash, OJ Kane, LE Martinez, Y Nahmias, N Bourne, ... Hepatology 51 (6), 1912-1921, 2010 | 328 | 2010 |
| Elevated levels of interleukin-8 in serum are associated with hepatitis C virus infection and resistance to interferon therapy SJ Polyak, KSA Khabar, M Rezeiq, DR Gretch Journal of virology 75 (13), 6209-6211, 2001 | 317 | 2001 |
| Uncovering biologically significant lipid isomers with liquid chromatography, ion mobility spectrometry and mass spectrometry JE Kyle, X Zhang, KK Weitz, ME Monroe, YM Ibrahim, RJ Moore, J Cha, ... Analyst 141 (5), 1649-1659, 2016 | 281 | 2016 |
| Myeloid suppressor cells induced by hepatitis C virus suppress T‐cell responses through the production of reactive oxygen species RS Tacke, HC Lee, C Goh, J Courtney, SJ Polyak, HR Rosen, YS Hahn Hepatology 55 (2), 343-353, 2012 | 254 | 2012 |
| A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection JA Mengshol, L Golden-Mason, T Arikawa, M Smith, T Niki, R McWilliams, ... PloS one 5 (3), e9504, 2010 | 240 | 2010 |
| Subversion of cell signaling pathways by hepatitis C virus nonstructural 5A protein via interaction with Grb2 and P85 phosphatidylinositol 3-kinase Y He, H Nakao, SL Tan, SJ Polyak, P Neddermann, S Vijaysri, BL Jacobs, ... Journal of virology 76 (18), 9207-9217, 2002 | 233 | 2002 |
| The synthetic antiviral drug arbidol inhibits globally prevalent pathogenic viruses EI Pécheur, V Borisevich, P Halfmann, JD Morrey, DF Smee, M Prichard, ... Journal of virology 90 (6), 3086-3092, 2016 | 201 | 2016 |
| Characterization of the effects of hepatitis C virus nonstructural 5A protein expression in human cell lines and on interferon‐sensitive virus replication SJ Polyak, DM Paschal, S McArdle, MJ Jr, D Moradpour, DR Gretch Hepatology 29 (4), 1262-1271, 1999 | 188 | 1999 |
| Hepatoprotective and antiviral functions of silymarin components in hepatitis C virus infection SJ Polyak, P Ferenci, JM Pawlotsky Hepatology 57 (3), 1262-1271, 2013 | 187 | 2013 |
| Evolution of hepatitis C virus quasispecies in hypervariable region 1 and the putative interferon sensitivity-determining region during interferon therapy and natural infection SJ Polyak, S McArdle, SL Liu, DG Sullivan, M Chung, WT Hofgärtner, ... Journal of virology 72 (5), 4288-4296, 1998 | 187 | 1998 |
| Silymarin inhibits in vitro T-cell proliferation and cytokine production in hepatitis C virus infection C Morishima, MC Shuhart, CC Wang, DM Paschal, MC Apodaca, Y Liu, ... Gastroenterology 138 (2), 671-681. e2, 2010 | 186 | 2010 |
| Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism J Goldwasser, PY Cohen, W Lin, D Kitsberg, P Balaguer, SJ Polyak, ... Journal of hepatology 55 (5), 963-971, 2011 | 182 | 2011 |
Michael Gale, Jr.University of WashintonVerified email at uw.edu
