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Gregory T Tietjen
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A holistic approach to targeting disease with polymeric nanoparticles
CJ Cheng, GT Tietjen, JK Saucier-Sawyer, WM Saltzman
Nature reviews Drug discovery 14 (4), 239-247, 2015
5522015
Nanoparticle targeting to the endothelium during normothermic machine perfusion of human kidneys
GT Tietjen, SA Hosgood, J DiRito, J Cui, D Deep, E Song, JR Kraehling, ...
Science translational medicine 9 (418), eaam6764, 2017
1762017
Focus on fundamentals: achieving effective nanoparticle targeting
GT Tietjen, LG Bracaglia, WM Saltzman, JS Pober
Trends in molecular medicine 24 (7), 598-606, 2018
1472018
Surface chemistry governs cellular tropism of nanoparticles in the brain
E Song, A Gaudin, AR King, YE Seo, HW Suh, Y Deng, J Cui, GT Tietjen, ...
Nature communications 8 (1), 15322, 2017
1202017
Quantitating endosomal escape of a library of polymers for mRNA delivery
Y Jiang, Q Lu, Y Wang, E Xu, A Ho, P Singh, Y Wang, Z Jiang, F Yang, ...
Nano letters 20 (2), 1117-1123, 2020
1112020
Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells
J Cui, L Qin, J Zhang, P Abrahimi, H Li, G Li, GT Tietjen, G Tellides, ...
Nature communications 8 (1), 191, 2017
1062017
A Molecular Mechanism for Differential Recognition of Membrane Phosphatidylserine by the Immune Regulatory Receptor Tim4
GT Tietjen, Z Gong, CH Chen, E Vargas, JE Crooks, KD Cao, CTR Heffern, ...
Biophysical Journal 106 (2), 17a, 2014
1012014
The future of marginal kidney repair in the context of normothermic machine perfusion
JR DiRito, SA Hosgood, GT Tietjen, ML Nicholson
American Journal of Transplantation 18 (10), 2400-2408, 2018
902018
Cellular recovery after prolonged warm ischaemia of the whole body
D Andrijevic, Z Vrselja, T Lysyy, S Zhang, M Skarica, A Spajic, D Dellal, ...
Nature 608 (7922), 405-412, 2022
872022
Lysis of cold-storage-induced microvascular obstructions for ex vivo revitalization of marginal human kidneys
JR DiRito, SA Hosgood, M Reschke, C Albert, LG Bracaglia, ...
American Journal of Transplantation 21 (1), 161-173, 2021
812021
A “top-down” approach to actuate poly (amine-co-ester) terpolymers for potent and safe mRNA delivery
Y Jiang, A Gaudin, J Zhang, T Agarwal, E Song, AC Kauffman, GT Tietjen, ...
Biomaterials 176, 122-130, 2018
772018
Differential functional roles of fibroblasts and pericytes in the formation of tissue-engineered microvascular networks in vitro
N Kosyakova, DD Kao, M Figetakis, F López-Giráldez, S Spindler, ...
NPJ Regenerative medicine 5 (1), 1, 2020
722020
Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression
J Merola, M Reschke, RW Pierce, L Qin, S Spindler, T Baltazar, TD Manes, ...
JCI insight 4 (20), e129739, 2019
412019
ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes
C Fang, TD Manes, L Liu, K Liu, L Qin, G Li, Z Tobiasova, ...
Nature communications 10 (1), 2247, 2019
412019
Nanomedicine gets personal
GT Tietjen, WM Saltzman
Science translational medicine 7 (314), 314fs47-314fs47, 2015
392015
Poly (amine-co-ester) nanoparticles for effective Nogo-B knockdown in the liver
J Cui, AS Piotrowski-Daspit, J Zhang, M Shao, LG Bracaglia, T Utsumi, ...
Journal of Controlled Release 304, 259-267, 2019
352019
Interferon-γ converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2, 3-dioxygenase 1
R Liu, J Merola, TD Manes, L Qin, GT Tietjen, F López-Giráldez, ...
JCI insight 3 (5), e97881, 2018
262018
Monobody adapter for functional antibody display on nanoparticles for adaptable targeted delivery applications
C Albert, L Bracaglia, A Koide, J DiRito, T Lysyy, L Harkins, C Edwards, ...
Nature Communications 13 (1), 5998, 2022
232022
Enhancing potency of siRNA targeting fusion genes by optimization outside of target sequence
K Gavrilov, YE Seo, GT Tietjen, J Cui, CJ Cheng, WM Saltzman
Proceedings of the National Academy of Sciences 112 (48), E6597-E6605, 2015
232015
High-throughput quantitative microscopy-based half-life measurements of intravenously injected agents
LG Bracaglia, AS Piotrowski-Daspit, CY Lin, ZM Moscato, Y Wang, ...
Proceedings of the National Academy of Sciences 117 (7), 3502-3508, 2020
202020
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