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WO2003029218A1 - Novel nitrogenous compound and use thereof - Google Patents

Novel nitrogenous compound and use thereof Download PDF

Info

Publication number
WO2003029218A1
WO2003029218A1 PCT/JP2002/010069 JP0210069W WO03029218A1 WO 2003029218 A1 WO2003029218 A1 WO 2003029218A1 JP 0210069 W JP0210069 W JP 0210069W WO 03029218 A1 WO03029218 A1 WO 03029218A1
Authority
WO
WIPO (PCT)
Prior art keywords
nitrogenous compound
formula
hydrogen
substituted
aromatic ring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2002/010069
Other languages
English (en)
French (fr)
Inventor
Toru Yamazaki
Atsushi Saitou
Masahiro Ono
Sei Yokoyama
Kenji Bannai
Kunitaka Hirose
Mikiro Yanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kureha Corp
Original Assignee
Kureha Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kureha Corp filed Critical Kureha Corp
Priority to JP2003532468A priority Critical patent/JPWO2003029218A1/ja
Priority to US10/487,718 priority patent/US20040254221A1/en
Priority to EP02768118A priority patent/EP1431290A4/en
Publication of WO2003029218A1 publication Critical patent/WO2003029218A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PCT/JP2002/010069 2001-09-28 2002-09-27 Novel nitrogenous compound and use thereof Ceased WO2003029218A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2003532468A JPWO2003029218A1 (ja) 2001-09-28 2002-09-27 新規含窒素化合物及びその用途
US10/487,718 US20040254221A1 (en) 2001-09-28 2002-09-27 Novel Nitrogenous Compound and use thereof
EP02768118A EP1431290A4 (en) 2001-09-28 2002-09-27 NITROGEN COMPOUND AND CORRESPONDING USE

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001-302584 2001-09-28
JP2001302584 2001-09-28

Publications (1)

Publication Number Publication Date
WO2003029218A1 true WO2003029218A1 (en) 2003-04-10

Family

ID=19122802

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/010069 Ceased WO2003029218A1 (en) 2001-09-28 2002-09-27 Novel nitrogenous compound and use thereof

Country Status (4)

Country Link
US (1) US20040254221A1 (ja)
EP (1) EP1431290A4 (ja)
JP (1) JPWO2003029218A1 (ja)
WO (1) WO2003029218A1 (ja)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005085209A1 (ja) * 2004-03-10 2005-09-15 Kureha Corporation アミン系塩基性化合物とその用途
WO2006022454A1 (ja) * 2004-08-27 2006-03-02 Ono Pharmaceutical Co., Ltd 塩基性基を含有する化合物およびその用途
US7176227B2 (en) 2002-09-11 2007-02-13 Kureha Corporation Amine compounds and use thereof
WO2007049771A1 (ja) 2005-10-28 2007-05-03 Ono Pharmaceutical Co., Ltd. 塩基性基を含有する化合物およびその用途
WO2007058322A1 (ja) 2005-11-18 2007-05-24 Ono Pharmaceutical Co., Ltd. 塩基性基を含有する化合物およびその用途
WO2007132846A1 (ja) * 2006-05-16 2007-11-22 Ono Pharmaceutical Co., Ltd. 保護されていてもよい酸性基を含有する化合物およびその用途
US7977512B2 (en) 2005-08-22 2011-07-12 Kureha Corporation Amine derivative, and production method and use thereof
US8008312B2 (en) 2005-01-07 2011-08-30 Emory University CXCR4 antagonists for the treatment of HIV infection
US8080659B2 (en) 2006-07-11 2011-12-20 Emory University CXCR4 antagonists including diazine and triazine structures for the treatment of medical disorders
US8338448B2 (en) 2008-03-28 2012-12-25 Altiris Therapeutics, Inc. Chemokine receptor modulators

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001079168A1 (en) * 2000-04-14 2001-10-25 Kureha Chemical Industry Co., Ltd. Nitrogenous compounds and antiviral drugs containing the same
WO2002094261A1 (fr) * 2001-05-24 2002-11-28 Kureha Chemical Industry Company, Limited Medicaments antagonistes de cxcr4 comprenant un compose contenant de l'azote
JP4710606B2 (ja) * 2003-04-18 2011-06-29 小野薬品工業株式会社 スピロピペリジン化合物およびその医薬用途
EP2397148A3 (en) 2006-02-02 2012-04-25 Allergan, Inc. Compositions and methods for the treatment of ophthalmic disease
US20080227799A1 (en) * 2006-07-11 2008-09-18 Liotta Dennis C CXCR4 Antagonists Including Heteroatoms for the Treatment of Medical Disorders
WO2012149102A1 (en) * 2011-04-29 2012-11-01 Glaxosmithkline Llc Novel compounds as wip1 inhibitors
US20220144853A1 (en) 2019-03-29 2022-05-12 Université de Paris Imidazoline derivatives as cxcr4 modulators
AU2021349324A1 (en) 2020-09-28 2023-05-18 Centre National De La Recherche Scientifique Cyclic isothiourea derivatives as cxcr4 modulators

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0183271A2 (en) * 1984-11-30 1986-06-04 Shosuke Okamoto Lysin derivative and proteinase inhibitor
WO2001079168A1 (en) * 2000-04-14 2001-10-25 Kureha Chemical Industry Co., Ltd. Nitrogenous compounds and antiviral drugs containing the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5086069A (en) * 1990-02-05 1992-02-04 Rorer Pharmaceutical Corporation Anti-thrombotic peptide and pseudopeptide derivatives
ID28658A (id) * 1998-04-16 2001-06-21 Texas Biotechnology Corp Senyawa yang menghambat pengikatan integrin pada reseptornya
WO2002094261A1 (fr) * 2001-05-24 2002-11-28 Kureha Chemical Industry Company, Limited Medicaments antagonistes de cxcr4 comprenant un compose contenant de l'azote

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0183271A2 (en) * 1984-11-30 1986-06-04 Shosuke Okamoto Lysin derivative and proteinase inhibitor
WO2001079168A1 (en) * 2000-04-14 2001-10-25 Kureha Chemical Industry Co., Ltd. Nitrogenous compounds and antiviral drugs containing the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1431290A4 *

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7176227B2 (en) 2002-09-11 2007-02-13 Kureha Corporation Amine compounds and use thereof
US7833991B2 (en) 2002-09-11 2010-11-16 Kureha Corporation Amine compound and use thereof
WO2005085209A1 (ja) * 2004-03-10 2005-09-15 Kureha Corporation アミン系塩基性化合物とその用途
US7932281B2 (en) 2004-03-10 2011-04-26 Kureha Corporation Amine-based compound and use thereof
KR101149124B1 (ko) 2004-03-10 2012-05-25 가부시끼가이샤 구레하 아민계 염기성 화합물과 그의 용도
WO2006022454A1 (ja) * 2004-08-27 2006-03-02 Ono Pharmaceutical Co., Ltd 塩基性基を含有する化合物およびその用途
US8822459B2 (en) 2004-08-27 2014-09-02 Ono Pharmaceutical Co., Ltd. Compound containing basic group and use thereof
JP5135795B2 (ja) * 2004-08-27 2013-02-06 小野薬品工業株式会社 塩基性基を含有する化合物およびその用途
JP2012131820A (ja) * 2004-08-27 2012-07-12 Ono Pharmaceut Co Ltd 塩基性基を含有する化合物およびその用途
JPWO2006022454A1 (ja) * 2004-08-27 2008-05-08 小野薬品工業株式会社 塩基性基を含有する化合物およびその用途
US7951816B2 (en) 2004-08-27 2011-05-31 Ono Pharmaceutical Co., Ltd. Compound containing basic group and use thereof
US20110142856A1 (en) * 2004-08-27 2011-06-16 Ono Pharmaceutical Co., Ltd. Compound containing basic group and use thereof
US8008312B2 (en) 2005-01-07 2011-08-30 Emory University CXCR4 antagonists for the treatment of HIV infection
US8114884B2 (en) 2005-01-07 2012-02-14 Emory University CXCR4 antagonists for the treatment of medical disorders
US7977512B2 (en) 2005-08-22 2011-07-12 Kureha Corporation Amine derivative, and production method and use thereof
EP2657235A1 (en) 2005-10-28 2013-10-30 Ono Pharmaceutical Co., Ltd. Compound containing basic group and use thereof
WO2007049771A1 (ja) 2005-10-28 2007-05-03 Ono Pharmaceutical Co., Ltd. 塩基性基を含有する化合物およびその用途
US8168783B2 (en) 2005-11-18 2012-05-01 Ono Pharmaceutical Co., Ltd. Chemokine receptor antagonists and use thereof
WO2007058322A1 (ja) 2005-11-18 2007-05-24 Ono Pharmaceutical Co., Ltd. 塩基性基を含有する化合物およびその用途
US8519124B2 (en) 2005-11-18 2013-08-27 Ono Pharmaceutical Co., Ltd. Chemokine receptor antagonists and use thereof
WO2007132846A1 (ja) * 2006-05-16 2007-11-22 Ono Pharmaceutical Co., Ltd. 保護されていてもよい酸性基を含有する化合物およびその用途
JP5257068B2 (ja) * 2006-05-16 2013-08-07 小野薬品工業株式会社 保護されていてもよい酸性基を含有する化合物およびその用途
US8618122B2 (en) 2006-05-16 2013-12-31 Ono Pharmaceutical Co., Ltd. Compound having acidic group which may be protected, and use thereof
US8080659B2 (en) 2006-07-11 2011-12-20 Emory University CXCR4 antagonists including diazine and triazine structures for the treatment of medical disorders
US8338448B2 (en) 2008-03-28 2012-12-25 Altiris Therapeutics, Inc. Chemokine receptor modulators
US9314468B2 (en) 2008-03-28 2016-04-19 Altiris Therapeutics, Inc. Chemokine receptor modulators

Also Published As

Publication number Publication date
US20040254221A1 (en) 2004-12-16
EP1431290A1 (en) 2004-06-23
EP1431290A4 (en) 2004-12-15
JPWO2003029218A1 (ja) 2005-01-13

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