US20080228265A1 - Tissue anchors, systems and methods, and devices - Google Patents
Tissue anchors, systems and methods, and devices Download PDFInfo
- Publication number
- US20080228265A1 US20080228265A1 US11/685,240 US68524007A US2008228265A1 US 20080228265 A1 US20080228265 A1 US 20080228265A1 US 68524007 A US68524007 A US 68524007A US 2008228265 A1 US2008228265 A1 US 2008228265A1
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- anchor
- tissue
- suture
- tensile member
- catheter
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- Abandoned
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Definitions
- the present invention relates generally to tissue fastening and, more particularly, tissue fastening performed in a minimally invasive and percutaneous manner.
- FIGS. 1-4 solely for purposes of understanding the anatomy of a heart 10 , and specifically the left side of the heart 10 , the left atrium (LA) 12 and left ventricle (LV) 14 are shown.
- An aorta 16 receives oxygenated blood from left ventricle 14 through an aortic valve 18 , which serves to prevent regurgitation of blood back into left ventricle 14 .
- a mitral valve 20 is positioned between left atrium 12 and left ventricle 14 , and allows one-way flow of the oxygenated blood from the left atrium 12 to the left ventricle 14 .
- Mitral valve 20 which will be described below in more detail, includes an anterior leaflet 22 and a posterior leaflet 24 that are coupled to cordae tendonae 26 , 28 ( FIG. 4 ).
- Cordea tendonea 26 , 28 serve as “tension members” that prevent the leaflets 22 , 24 of mitral valve 20 from moving past their closing point and prolapsing back into the left atrium 12 .
- cordae tendonae 26 , 28 limit the upward motion (toward the left atrium) of the anterior and posterior leaflets 22 , 24 past the point at which the anterior and posterior leaflets 22 , 24 meet and seal to prevent backflow from the left ventricle 14 to the left atrium 12 (“mitral regurgitation” or “mitral insufficiency”).
- Cordae tendonae 26 , 28 arise from a columnae carnae or, more specifically, a musculi papillares (papillary muscles) of the columnae carnae. In various figures herein, some anatomical features have been deleted solely for clarity.
- Anterior leaflet 22 and posterior leaflet 24 of the mitral valve 20 are generally thin, flexible membranes. When mitral valve 20 is closed, anterior leaflet 22 and posterior leaflet 24 are generally aligned and contact one another along a “line of coaptation” several millimeters back from their free edges, to create a seal that prevents mitral regurgitation. Alternatively, when mitral valve 20 is opened, blood flows downwardly through an opening created between anterior leaflet 22 and posterior leaflet 24 into left ventricle 14 .
- Mitral regurgitation is the backflow of blood from left ventricle 14 into the left atrium 12 due to an imperfect closure of mitral valve 20 . That is, leakage often occurs when the anterior and posterior leaflets 22 , 24 do not seal against each other, resulting in a gap between anterior leaflet 22 and posterior leaflet 24 when the leaflets are supposed to be fully coapted during systole.
- a relatively significant systolic gap may exist between anterior leaflet 22 and posterior leaflet 24 for a variety of different reasons.
- a gap may exist due to congenital malformations, because of ischemic disease, or because the heart 10 has been damaged by a previous heart attack.
- Such a gap may also be created when congestive heart failure, e.g., cardiomyopathy, or some other type of distress which causes a heart 10 to be enlarged.
- Enlargement of the heart 10 can result in dilation (stretching) of the mitral annulus. This enlargement is usually limited to the posterior valve annulus and is associated with the posterior leaflet 24 , because the anterior annulus is a relatively rigid fibrous structure.
- the posterior annulus When the posterior annulus enlarges, it causes the posterior leaflet 24 to move away from the anterior leaflet 22 , causing a gap during systole because the two leaflets no longer form proper coaptation. This results in leakage of blood through the valve 20 , or regurgitation.
- Blood leakage through mitral valve 20 generally causes a heart 10 to operate less efficiently, as the heart 10 pumps blood both out to the body via the aorta 16 , and also back (in the form of mitral regurgitation) into the left atrium 12 .
- Leakage through mitral valve 20 or general mitral insufficiency, is thus often considered to be a precursor to congestive heart failure (CHF) or a cause of progressive worsening of heart failure.
- CHF congestive heart failure
- the levels range from a Class 1 level which is associated with an asymptomatic patient who has substantially no physical limitations to a Class 4 level which is associated with a patient who is unable to carry out any physical activity without discomfort and has symptoms of cardiac insufficiency even at rest.
- correcting or reducing the degree of mitral valve leakage may be successful in allowing the NYHA classification grade of a patient to be reduced.
- a patient with a Class 4 classification may have his classification reduced to Class 3 or Class 2 and, hence, be relatively comfortable at rest or even during mild physical exertion.
- therapies that reduce mitral insufficiency reduce the workload of the heart 10 and may prevent or slow the degradation of heart function and congestive heart failure symptoms that is common when a significant degree of mitral insufficiency remains uncorrected.
- Treatments used to correct for mitral valve leakage or, more generally, CHF are typically highly invasive, open-heart surgical procedures. In extreme cases, this may include implantation of a ventricular assist device such as an artificial heart in a patient with a failing heart.
- a ventricular assist device such as an artificial heart in a patient with a failing heart.
- the implantation of a ventricular assist device is often expensive, and a patient with a ventricular assist device must be placed on extended anti-coagulant therapy.
- Anti-coagulant therapy reduces the risk of blood clot formation for example, within the ventricular assist device. Reducing the risks of blood clots associated with the ventricular assist device is desirable, but anti-coagulant therapies may increase the risk of uncontrollable bleeding in a patient, e.g., as a result of a fall.
- bi-ventricular pacing devices similar to pacemakers may be implanted in some cases, e.g., cases in which a heart beats inefficiently in a particular asynchronous manner. While the implantation of a bi-ventricular pacing device may be effective, not all heart patients are suitable for receiving a bi-ventricular pacing device. Further, the implantation of a bi-ventricular pacing device is expensive, and is generally not effective in significantly reducing or eliminating the degree of mitral regurgitation.
- Open-heart surgical procedures that are intended to correct for mitral valve leakage can involve the implantation of a replacement valve.
- Valves from animals e.g., pigs
- a pig valve may relatively successfully replace a mitral valve, such replacement valves generally wear out, thereby requiring additional open surgery at a later date.
- Mechanical valves which are less likely to wear out, may also be used to replace a leaking mitral valve.
- a mechanical valve is implanted, there is an increased risk of thromboembolism, and a patient is generally required to undergo extended anti-coagulant therapies.
- a less invasive surgical procedure involves heart bypass surgery associated with a port access procedure.
- the heart may be accessed by cutting between ribs or sometimes removing parts of one or more ribs, as opposed to dividing the sternum to open the entire chest of a patient.
- annuloplasty procedure One open-heart surgical procedure that is particularly successful in correcting for mitral valve leakage and, in addition, mitral regurgitation, is an annuloplasty procedure.
- a medical device such as an annuloplasty ring may be implanted surgically on the left atrial side of mitral annulus (i.e., generally the attachment location of the base of the mitral valve to the heart).
- the device reduces a dilated mitral valve annulus to a relatively normal size and, specifically, moves the posterior leaflet closer to the anterior leaflet to aid anterior—posterior leaflet coaptation and thus improve the quality of mitral valve closure during systole.
- Annuloplasty rings are often shaped substantially like the letter “D” to correspond to the natural shape of the mitral annulus as viewed from above.
- the rings are formed from a rod or tube of biocompatible material, e.g., plastic, that has a DACRON mesh covering.
- annuloplasty ring In order for an annuloplasty ring to be implanted, a surgeon surgically attaches the annuloplasty ring to the mitral valve on the atrial side of the mitral valve.
- Conventional methods for installing a ring require open-heart surgery which involves opening a patient's sternum and placing the patient on a heart bypass machine.
- the annuloplasty ring is sewn on a top portion of the mitral valve.
- a surgeon In sewing the annuloplasty ring onto the mitral valve, a surgeon generally sews the straight side of the “D” to the fibrous tissue located at the junction between the posterior wall of the aorta and the base of the anterior mitral valve leaflet.
- the surgeon alternately acquires a relatively larger amount of tissue from the mitral annulus, e.g., a one-eighth inch bite of tissue, using a needle and thread, compared to a relatively smaller bite taken of the fabric covering of the annuloplasty ring.
- tissue of the posterior mitral annulus that was previously stretched out, e.g., due to an enlarged heart, is effectively reduced in circumference and pulled forwards towards the anterior mitral leaflet by the tension applied by annuloplasty ring with the suture or thread.
- a gap between anterior leaflet 22 and posterior leaflet 24 during ventricular contraction or systole may be reduced and even substantially closed off in many cases thereby significantly reducing or even eliminating mitral insufficiency.
- the anterior and posterior leaflets 22 , 24 will reform typically by pulling the posterior leaflet 24 forward to properly meet the anterior leaflet 22 and create a new contact line that will enable mitral valve 20 to appear and to function properly.
- the therapies are not extensive, as a patient is only subjected to the therapies for a matter of weeks, e.g., until tissue grows over the annuloplasty ring.
- Another type of procedure that is generally effective in reducing mitral valve leakage associated with prolapse of the valve leaflets involves placing a single edge-to-edge suture in the mitral valve 20 that apposes the mid-portions of anterior and posterior leaflets 22 , 24 .
- an edge-to-edge stitch is made at approximately the center of the gap between an anterior leaflet 22 and a posterior leaflet 24 of a mitral valve 20 .
- Another surgical procedure that reduces mitral valve leakage involves placing sutures along a mitral valve annulus around the posterior leaflet 24 .
- These sutures may be formed as a double track, e.g., in two “rows” from a single strand of suture material.
- the sutures are tied off at approximately a central point (P 2 ) of posterior leaflet 24 .
- P 2 central point
- Pledgets are often positioned under selected sutures to prevent the sutures from tearing through annulus 40 .
- the circumference of the annulus 40 may effectively be reduced to a desired size such that the size of a systolic gap between posterior leaflet 24 and an anterior leaflet 22 may be reduced.
- a cinching device is placed within the coronary sinus (CS) using a catheter system, with distal, mid, and proximal anchors within the lumen of the CS to allow plication of the annulus 40 via the CS.
- these anchors are cinched together and the distance between them is shortened by pulling a flexible tensile member such as a cable or suture with the intent being to shorten the valve annulus 40 and pull the posterior leaflet 24 closer to the anterior leaflet 22 in a manner similar to an annuloplasty procedure.
- a flexible tensile member such as a cable or suture
- the effect on the mitral annulus may be reduced when the CS of a particular patient is not directly aligned with the mitral annulus.
- Other minimally invasive techniques have been proposed but have various drawbacks related to such factors as effectiveness and/or accuracy of catheter-based implementation.
- a system for accurately introducing an element into tissue proximate (i.e., either at or close to) the mitral valve annulus of the heart of a patient.
- the element may be any desired structure suitable for the intended purpose.
- the element may advantageously comprise a guide wire.
- the system includes a first catheter device having a first distal end portion capable of being introduced through the vascular system of the patient and into the coronary sinus proximate the mitral valve annulus.
- the first catheter device includes first, second and third spaced apart radiopaque markers at the first distal end portion.
- the system further includes a second catheter device having a second distal end portion capable of being introduced through the vascular system of the patient and into the left ventricle of the heart proximate the mitral valve annulus.
- the second catheter device includes a fourth radiopaque marker at the second distal end portion and a lumen for delivering an element from the second distal end portion.
- the fourth radiopaque marker may be aligned with reference to at least one of the first, second or third radiopaque markers to deliver the element into the mitral valve tissue.
- the fourth radiopaque marker is aligned with the first radiopaque marker of the first catheter device generally at location P 2 of the posterior mitral annulus.
- the first, second and third radiopaque markers may be spaced apart to correspond to locations P 1 , P 2 and P 3 of the posterior mitral valve annulus.
- a method for accurately introducing an element into tissue proximate the mitral valve annulus using a first catheter device having a first distal end portion with a first radiopaque marker and a second catheter device having a second distal end portion with a lumen comprises introducing the first distal end portion of the first catheter device through the vascular system of the patient and into the coronary sinus proximate the mitral valve annulus.
- the first radiopaque marker is positioned at a desired location in the coronary sinus proximate the mitral valve annulus.
- the second distal end portion of the second catheter device is introduced through the vascular system of the patient and into the heart proximate the mitral valve annulus.
- the second distal end portion is positioned in a desired orientation relative to the first radiopaque marker.
- the element is then delivered through the lumen into tissue proximate the mitral valve annulus with the second distal end portion in the desired orientation.
- the method of accurately introducing the element into tissue proximate the mitral valve annulus may further comprise delivering a first guide wire through the mitral valve annulus and into the left atrium of the heart from the left ventricle of the heart.
- the method may further comprise guiding a second element over the first guide wire to a position proximate the mitral valve annulus and the second element may further comprise a third catheter device.
- a second guide wire may be delivered from the third catheter device through the mitral valve annulus and into the left atrium of the heart from the left ventricle of the heart.
- the method may further comprise using the first and second guide wires to deliver first and second anchors, respectively, into the mitral valve annulus, shortening the distance between the first and second anchors, and locking the first and second anchors with respect to each other.
- This may, for example, form plicated annulus tissue helpful for reducing regurgitation through the mitral valve.
- a third guide wire may be delivered from the third catheter device through the mitral valve annulus and into the left atrium of the heart from the left ventricle of the heart. This third guide wire may be used to deliver a third anchor into the mitral valve annulus and the distance between at least two of the first, second or third anchors may be shortened and then at least these two anchors may be locked with respect to each other.
- the first distal end portion may further comprise two additional radiopaque markers spaced apart on opposite sides of the first radiopaque marker.
- the method may further comprise positioning the first radiopaque marker at a location in the coronary sinus proximate location P 2 of the mitral valve annulus, and positioning the two additional radiopaque markers in the coronary sinus respectively more proximate to locations P 1 and P 3 of the mitral valve annulus.
- the second distal end portion may further include a second radiopaque marker and positioning the second distal end may further comprise positioning the second radiopaque marker in a desired orientation relative to the first radiopaque marker.
- the first radiopaque marker may have a predetermined cross sectional shape (e.g., circular) when viewed directly along the longitudinal axis of the first catheter device.
- the method may further comprise viewing the first radiopaque marker directly along the longitudinal axis of the first catheter device while positioning the second distal end portion in the desired orientation.
- a catheter device capable of being directed through the vascular system of a patient and delivering first and second elements into tissue.
- the catheter device comprises first, second and third catheter members respectively including first, second and third lumens.
- a first connecting member is coupled between the first and second catheter members and a second connecting member coupled between the first and third catheter members.
- the second and third catheter members are laterally movable in generally opposite directions relative to the first catheter member between collapsed positions suitable for delivery of the first, second and third catheter members through the vascular system and expanded positions in which the second and third catheter members are at laterally spaced apart positions relative to the first catheter member for delivering the first and second elements into the tissue through the second and third lumens.
- the catheter device may further comprise a third connecting member coupled between the first and second catheter members and a fourth connecting member coupled between the first and third catheter members.
- the first, second, third and fourth connecting members may further comprise bars pivotally coupled between the first, second and third catheter members.
- the device may further comprise an outer catheter member or sheath having a fourth lumen with the fourth lumen receiving the first, second and third catheter members.
- the first, second and third catheter members may therefore be a triple lumen catheter received within and extendable from the distal end of an outer sheath.
- the second and third catheter members may be movable in a lengthwise direction relative to the first catheter member as the second and third catheter members move laterally to the expanded positions.
- the catheter device including the triple lumen catheter, or first, second and third catheter members may further comprise first, second and third guide wires respectively received in the first, second and third lumens.
- the first guide wire may be used as an initial guide for delivery of the catheter device to a surgical site, such as within the left ventricle of the heart, and the second and third guide wires may be extendable from the device into tissue, such as mitral valve annulus tissue.
- the first, second and third guide wires may further comprise radiofrequency (RF) energy delivery wires capable of applying radiofrequency energy to assist with penetrating the tissue.
- RF radiofrequency
- a method for delivering respective elements into spaced apart locations along an annulus of a mitral valve using a catheter device including first, second and third catheter members that respectively include first, second and third lumens.
- the method comprises directing a first guide wire through the vascular system and into the heart of a patient.
- the first, second and third catheter members are introduced through the vascular system and into the heart of the patient with the first guide wire received in the first lumen and with the first, second and third catheter members are in a collapsed state relative to one another.
- Distal end portions of the first, second and third catheter members are positioned proximate the annulus.
- the distal end portions of the second and third catheter members are expanded laterally away from the first catheter member.
- the respective elements are then delivered respectively into tissue proximate the annulus through the second and third lumens.
- the method of delivering respective elements into spaced apart locations along the annulus may further comprise delivering second and third guide wires respectively through the second and third lumens.
- the method may further comprise applying radiofrequency energy with distal tip portions of the second and third guide wires to assist with penetrating through the tissue.
- the distal end portions of the first, second and third guide wires may be extended into the left atrium of the heart.
- the method may then further comprise delivering first, second and third anchors into the tissue using the first, second and third guide wires as guides to the spaced apart locations.
- the first, second and third anchors may be connected to the tissue. Distances between two or more of the anchors may be shortened and locked in position as generally described above.
- Respective first, second and third flexible tensile member portions may be coupled to the first, second and third anchors and locking the first, second and third anchors may further comprise locking at least two of the first, second or third flexible tensile member portions together.
- the flexible tensile member portions may be comprised of any suitable material having requisite strength, flexibility and biocompatibility.
- any suitable suture material which may be portions of the same suture material, or discrete and separate suture threads having respective free ends, may be used.
- the first, second and third anchors may be respectively secured to the first, second and third flexible tensile members to form first, second and third anchor assemblies. These anchor assemblies may be delivered to the spaced apart locations via at least one anchor delivery catheter. In an illustrative embodiment, these anchor assemblies are individually delivered to the left ventricle via individual, separate anchor delivery catheters.
- a tissue anchor in another embodiment, is provided generally comprising a flexible tensile member and a plurality of discrete, flat flexible anchor elements coupled for movement along the flexible tensile member to form one illustrative embodiment of an anchor assembly.
- the flexible tensile member and at least one of the plurality of discrete, flat flexible anchor elements are capable of being inserted through tissue and of moving between an elongate configuration and a shortened configuration suitable for anchoring the assembly against at least one side of the tissue.
- This anchor assembly includes a proximal end portion, a distal end portion, and a compressible intermediate portion between the proximal and distal end portions.
- the compressible intermediate portion is compressible in that it may be shortened during an anchoring process.
- it may comprise multiple anchor elements itself, or more simply a space between proximal and distal anchor elements connected by the flexible tensile member.
- the anchor elements can slide relative to the flexible tensile member and the flexible tensile member is capable of being pulled to cause the anchor elements to move relative to the flexible tensile member from the elongate configuration to the shortened configuration.
- the anchor elements may be formed from any suitable biocompatible material.
- the material may be selected from at least one of natural fibers, synthetic fibers, polymers, metals or any combinations thereof (i.e., combinations with one another and/or with other materials).
- the anchor elements are formed of material that promotes tissue ingrowth such that after implantation, the anchor assembly will be essentially covered by natural tissue of the patient.
- the flexible tensile member may comprise a suture having a suitable lock member, such as a simple slip knot for allowing the proximal end of the flexible tensile member to be pulled causing movement of the slip knot distally and resulting in compression or relative movement of two or more anchor elements toward each other.
- the flexible tensile member may extend through each of the anchor elements at multiple locations and one or more of the anchor elements and/or the flexible tensile member, or both, may have at least one radiopaque marker to allow visualization under a suitable viewing device such as a fluoroscope during and/or after the anchor installation procedure.
- a suitable viewing device such as a fluoroscope
- the plurality of discrete, flat flexible anchor elements may have any suitable shape.
- the anchor elements are sufficiently flexible to allow contraction or folding into an anchor delivery catheter and subsequent expansion or unfolding after deployment from the anchor delivery catheter to provide a wider retaining surface against the tissue.
- a deploying device may be operatively associated with the anchor delivery catheter and operable to extend or deploy the anchor assembly from the anchor delivery catheter.
- this deploying device may further comprise a deploying member, such as a flexible rod or inner deployment catheter, capable of pushing the anchor assembly at least partially out of the lumen of the anchor delivery catheter.
- a method for anchoring tissue with a first anchor assembly comprised of a first plurality of discrete, flat flexible anchor elements.
- the first anchor assembly includes a proximal end portion, a distal end portion and a compressible intermediate portion located between the proximal and distal end portions and movable between an elongated configuration and a shortened configuration.
- the method comprises inserting at least one of the anchor elements through the tissue and pulling a first flexible tensile member coupled for sliding movement relative to the first plurality of discrete, flat flexible anchor elements. This draws the proximal and distal end portions of the first anchor assembly toward each other and compresses the intermediate portion into the shortened configuration with the assembly engaged against the tissue.
- the tissue may comprise the mitral valve annulus and the first anchor assembly may be engaged on opposite sides of the tissue, such as on opposite sides of the mitral valve annulus.
- the method may further comprise inserting second and even third anchor assemblies through the tissue at spaced apart locations from the first anchor assembly and drawing the two or three anchor assemblies toward each other to plicate the tissue whereupon the anchor assemblies are locked relative to each other to lock the plicated condition of the tissue. This procedure may, for example, be repeated any number of times to plicate the posterior portion of the mitral valve annulus for purposes of achieving annuloplasty.
- a suture cutter for percutaneously cutting a suture located within a patient.
- the suture cutter may comprise an actuator for manipulation by a medical professional and an intermediate catheter portion operatively coupled to the actuator for insertion into the vascular system of the patient.
- a cutting assembly is operatively coupled to the intermediate catheter portion and the actuator.
- the cutting assembly includes a blade housing and a blade with a cutting edge mounted for movement in the blade housing.
- An adjustably sized cutting window is defined between the cutting edge and the blade housing and the cutting edge cuts a suture received inside of the cutting window as the cutting edge moves in the blade housing to reduce the size of the cutting window.
- an anvil may be positioned on an opposite side of the cutting window from the cutting edge and the suture may be cut against the anvil.
- a blade receiving slot may be located on an opposite side of the cutting window from the cutting edge and the suture may be cut as the blade moves into the blade receiving slot.
- the blade housing may further comprise a first aperture on one side of the blade and a second aperture on an opposite side of the blade such that the suture is adapted to pass from the first aperture to the second aperture through the cutting window.
- a method of cutting a suture located within a patient involves positioning a suture cutter within the patient, with the suture cutter including a blade movable through an adjustably sized cutting window.
- a suture is directed through the cutting window, such as at a time before the suture cutter is directed into the patient through the vascular system.
- the size of the cutting window is reduced by moving the blade towards the suture and the suture is then cut with the blade, either against an anvil or by directing the blade into a blade receiving space past the suture (e.g., into a slot).
- the suture cutter may be directed through a catheter leading into the vascular system of the patient.
- the suture cutter may be used, for example, to cut the tails from the sutures used during one or more of the annuloplasty procedures described herein.
- a plication assistance device may be used, for example, to tension and lock the flexible tensile members described herein.
- the device comprises a support structure and a first carriage fixed to the support structure and configured to hold an outer plication catheter.
- a second carriage is fixed to the support structure at a location proximal to the first carriage. At least one of the first or second carriages is slidable along the support structure and capable of being locked in position relative to the support structure.
- the second or proximal carriage is configured to hold an inner plication catheter.
- a first suture tensioning mechanism is mounted to the support structure at a location proximal to the second carriage and a second suture tensioning mechanism is mounted to the support structure also at a location proximal to the second carriage.
- the plication assistance device may further comprise a third suture tensioning mechanism mounted to the support structure at a location proximal to the second carriage.
- the first and second suture tensioning mechanisms may further comprise first and second rotatable spools.
- the first and second carriages may respectively include first and second locking devices for securing the outer plication catheter and inner plication catheter thereto.
- the plication assistance device may include a suture tension gauge operatively connected with the support structure and configured to measure tension of a suture being tensioned by at least one of the first or second suture tensioning mechanisms.
- FIG. 1 is a schematic illustration of a patient with the anatomy of the heart in cross section and a guide catheter introduced through the vascular system into the aorta and heart of the patient.
- FIG. 2 is a cross sectional view of the heart from above showing the introduction of various catheters.
- FIG. 3 is a cross sectional view of the heart similar to FIG. 2 and illustrating the further introduction of a guide wire.
- FIG. 4 is a partial longitudinal cross sectional view of the heart showing the positioning of the catheters in the left ventricle and coronary sinus.
- FIG. 5 is a cross sectional view of the heart similar to FIG. 4 , but illustrating the further introduction of a guide wire through the mitral valve annulus.
- FIG. 6 is an enlarged view of the mitral valve in cross section and showing the introduction of an expandable triple lumen catheter into the left ventricle.
- FIG. 7 is a cross sectional view of the mitral valve similar to FIG. 6 and showing the further introduction of the expandable triple lumen catheter.
- FIG. 8 is a cross sectional view of the heart similar to FIG. 7 , but illustrating the initial expansion of the triple lumen catheter.
- FIG. 9 is an elevational view of the expanding triple lumen catheter relative to the mitral valve annulus.
- FIG. 10 is a view similar to FIG. 9 , but showing the full expansion of the triple lumen catheter.
- FIG. 11 is an elevational view showing the introduction of an anchor delivery catheter over one of the guide wires.
- FIG. 12 is a view similar to FIG. 11 , but showing the initial deployment of the anchor from the anchor delivery catheter.
- FIG. 12A is a view similar to FIG. 12 , but showing a portion of the anchor compressed or shortened on a distal side of the tissue.
- FIG. 13 is a view similar to FIG. 12 , but illustrating the full deployment of the anchor from the anchor delivery catheter and the anchor delivery catheter being retracted.
- FIG. 14 is a view similar to FIG. 13 , but illustrating deployment of a second anchor from an anchor delivery catheter.
- FIG. 15 is a view similar to FIG. 14 , but showing the deployment of a third anchor from an anchor delivery catheter and retraction of the anchor delivery catheter.
- FIG. 16 is an elevational view showing the deployment of a suture locker over the three sutures associated with the respective anchors.
- FIGS. 16A , 16 B and 16 C are enlarged views showing the progressive deployment and locking of the suture locker onto the three sutures.
- FIG. 16D is a longitudinal cross sectional view of the suture locker showing the locked condition.
- FIG. 17 is an elevational view showing retraction of the plication catheter and the mitral valve annulus in a plicated condition.
- FIG. 18 is a perspective view of a plication assistance device useful for tensioning the sutures and deploying the suture locker.
- FIGS. 18A and 18B are respective partially cross sectioned views of a tension gauge associated with the plication assistance device of FIG. 18 with the sections taken lengthwise along the gauge.
- FIG. 19 is an elevational view showing the introduction of a suture cutter catheter for cutting the suture material extending from the suture locker.
- FIGS. 20A , 20 B and 20 C are cross sectional views of the distal end portion of the suture cutter showing the suture cutting operation.
- FIG. 21 is a cross sectional view of the locked anchor assembly on the plicated annulus.
- FIG. 22 is a cross sectioned view of the mitral valve showing the locked anchor assembly.
- FIG. 23 is a perspective view of a first alternative anchor.
- FIG. 24 is a perspective view of a second alternative anchor.
- FIG. 25 is an elevational view of a third alternative anchor.
- proximal and distal are used, as conventional in the art, to denote spatial relationship relative to the person using the particular device or component. That is, “proximal” refers to a position closer to the user and “distal” refers to a position farther from the user.
- a guide catheter 50 is illustrated as being directed into the vascular system of a patient, such as through an artery in the groin region of the patient, as shown in FIG. 1 .
- the guide catheter 50 may be a 12 mm catheter directed through the vascular system in any suitable manner.
- guide catheter 50 is directed into the aorta 16 , through the aortic valve 18 and into the left ventricle 14 between the pair of cordae tendonae 26 , 28 as best shown in FIG. 4 .
- This guide catheter 50 is then used as a guide sheath or tube for guiding all of the subsequent catheter devices into the left ventricle 14 for use in a method of plicating the annulus 40 of the mitral valve 20 .
- a P 2 catheter 52 is inserted to the guide catheter 50 .
- P 2 refers to the central location of the base of the posterior leaflet 24 along the annulus 40 .
- the P 2 catheter 52 may have a deflectable tip to allow more accurate and easier manipulation and location of the catheter tip relative to the annulus 40 .
- the catheter tip can include a radiopaque marker 52 a visible under a fluoroscope.
- a coronary sinus or CS catheter 56 is directed into the coronary sinus 36 via the vascular system of the patient, such as through an entry point in the jugular vein of the patient and subsequently through the right atrium 38 as shown best in FIGS. 2 and 3 .
- the CS catheter 56 is directed into the coronary sinus 36 as shown in FIG. 3 such that three radiopaque markers 56 a , 56 b , 56 c on or in the catheter 56 are located generally at positions approximating P 1 , P 2 and P 3 along the mitral valve annulus 40 .
- the coronary sinus 36 runs generally along the mitral valve annulus 40 in most patients and therefore provides a good location for placement of markers 56 a , 56 b , 56 c .
- the distal tip 52 a of the P 2 catheter 52 is aligned at the annulus 40 as shown in FIG. 4 such that it is directed upward at the interior of the left atrium 12 .
- Radiopaque marker 56 b in the coronary sinus 36 is used to determine and ensure proper placement of the distal tip 52 a at the P 2 location along the annulus 40 .
- Contrast media injections into the LV and/or LA may also be made to confirm positioning under a fluoroscope, for example.
- a first RF guide wire may be introduced through the P 2 catheter.
- the P 2 guide wire may have a radio frequency (RF) energy delivery tip 60 a for assisting with penetration through mitral tissue generally at the annulus 40 .
- RF radio frequency
- a suitable RF energy device (not shown) may be coupled to guide wire 60 , as well as the other RF guide wires disclosed hereinbelow.
- the distal portion of the P 2 guide wire 60 then extends into the left atrium and curls back on itself to help prevent tissue damage within the left atrium 12 as shown best in FIG. 6 .
- triple lumen catheter 70 contained within a sheath 72 .
- Triple lumen catheter 70 and sheath 72 are introduced into the guide catheter 50 after withdrawal of the P 2 catheter 52 therefrom.
- Triple lumen catheter 70 more specifically comprises a central or first catheter member 74 having a lumen 74 a threaded over the P 2 guide wire 60 .
- triple lumen catheter 70 further comprises second and third catheter members 76 , 78 respectively corresponding generally to the P 1 and P 3 locations generally along the posterior mitral annulus 40 .
- the second and third catheter members 76 , 78 also include respective lumens 76 a , 78 a containing respective guide wires 62 and 64 . It will be appreciated that other locations along the annulus 40 may be chosen in addition to or instead of those discussed illustratively herein.
- the combined triple lumen catheter 70 and sheath 72 are pushed through the guide catheter 50 and an expandable distal portion comprised of catheter members 74 , 76 , 78 is then extended from the sheath 72 in the left ventricle 14 of the patient.
- the initial positioning of the P 2 guide wire 60 ensures that the middle or P 2 catheter member 74 will be an accurate reference point at P 2 .
- the triple lumen catheter 70 is pushed outward from the distal end of the sheath 72 and expansion takes place as shown in FIGS. 8 and 9 . As best shown in FIG.
- the two outer catheter members 76 , 78 (that is, the P 1 and P 3 catheter members) automatically expand outward due to their coupling with the central or P 2 catheter member 74 by way of connecting bars 80 , 82 , 84 , 86 .
- These connecting bars may, for example, be formed from thin metallic plate material such as superelastic material, stainless steel, other metals or combinations of materials. It has been found that a thin plate of NitinolTM (nickel-titanium) stacked adjacent to a thin plate of stainless steel works well for each connecting bar 80 , 82 , 84 , 86 .
- the Nitinol exhibits spring characteristics effective for the expansion of the two outer catheter members 76 , 78 away from the inner or central catheter member 74 , while the stainless steel plate of each connecting bar provides additional stiffness for support purposes.
- Respective connectors 88 , 90 , 92 , 94 , 96 , 98 couple each connecting bar 80 , 82 , 84 , 86 to the respective catheter members 76 , 74 , 78 as shown in FIG. 9 with a living hinge adjacent each connector 88 , 90 , 92 , 94 , 96 , 98 .
- This illustrative structure therefore essentially forms two four-bar type linkage structures with one being formed by catheter members 74 , 76 and bars 80 , 84 and the other being formed by catheter members 74 , 78 and bars 82 , 86 .
- This expandable structure therefore causes the two outer catheter members 76 , 78 to translate distally and also expand laterally outward to known positions dictated by the respective lengths of the bars 80 , 82 , 84 , 86 .
- the distal end of catheter 76 is ultimately positioned approximately at position P 1 along the mitral annulus 40
- the distal end of catheter member 78 is positioned approximately at position P 3 along the mitral annulus 40 . It will be appreciated that these positions are representative and illustrative only and that the method may be performed at any other positions along the mitral annulus 40 depending on the desires of the surgeon and needs of the patient, for example.
- Catheter members 76 , 78 include lumens 76 a , 78 a from which the respective P 1 and P 3 guide wires 62 , 64 may be directed as shown in FIG. 10 .
- the P 1 and P 3 guide wires 62 , 64 may include RF or radiofrequency energy delivery tips 62 a , 64 a for assisting with penetration through the annulus tissue 40 .
- tissue tissue refers to tissue generally along the annulus 40 and may, in fact, be tissue on the base of the posterior leaflet 24 itself. As shown in FIG.
- these guide wires 62 a , 64 a may generally align with the radiopaque markers 56 a , 56 c of the CS catheter 56 located in the coronary sinus 36 ( FIG. 3 ).
- the RF guide wires 62 , 64 are inserted through the annulus tissue 40 such that distal portions thereof extend into the left atrium 12 in manners similar to RF guide wire 60 as generally shown in FIG. 6 .
- the triple lumen catheter 70 including the sheath 72 , is then removed from the guide catheter 50 .
- FIGS. 11-15 illustrate the procedure for attaching anchors to the annulus tissue 40 .
- FIG. 11 shows the initial introduction of a P 2 anchor delivery catheter 100 over P 2 guide wire 60 .
- the distal end 100 a of P 2 anchor delivery catheter 100 is pushed along RF guide wire 60 until it penetrates through the annulus tissue 40 .
- an anchor assembly 102 is partially deployed as shown.
- the anchor assembly 102 comprises a plurality of discrete, flat flexible anchor elements 104 coupled to a flexible tensile member, for example, in the form of a suture 106 .
- the guide wire 60 may be removed before or after the anchor deployment process.
- the P 2 anchor delivery catheter 100 is pulled back into the left ventricle 14 and the remaining proximal portion of the anchor assembly 102 is then deployed from the distal end 100 a such that a portion of the anchor elements 104 are located in the left atrium and another portion of the anchor elements are located in the left ventricle.
- the anchor elements 104 are coupled to the suture 106 , in this example, by threading the suture 106 upwardly through the elements 104 and then back downwardly through the anchor elements 104 as shown. A slip knot 108 is then formed, or another type of lock member is used, so that when a proximal end portion of the suture 106 is pulled, all of the anchor elements 104 will be drawn together against opposite sides of the annulus tissue 40 as shown in FIG. 14 . This leaves a long “tail” of the suture 106 outside the patient's body for subsequent tensioning and plication as will be described below.
- One or more of the anchor elements 104 may have a radiopaque marker 104 a for better visualization under a suitable viewing device during the procedure.
- one such marker may be located on a proximal portion of the anchor 102 and one may be located on a distal portion of the anchor 102 .
- the suture material or other flexible tension members discussed herein may have one or more radiopaque areas for better visualization.
- a P 1 anchor delivery catheter 110 is threaded over the P 1 guide wire 62 through guide catheter 50 after the P 2 anchor delivery catheter 100 has been removed.
- An anchor assembly 112 again comprised of discrete, flat flexible anchor elements 114 is deployed through a distal end 110 a of the P 1 anchor delivery catheter 110 in the same manner as described above with respect to anchor assembly 102 .
- anchor assembly 112 includes a flexible tensile member, such as a suture 116 , having a slip knot or other lock member for drawing the anchor elements 114 together against opposite sides of the annulus tissue 40 .
- FIG. 15 illustrates a third or P 3 anchor delivery catheter 120 used in the same manner as anchor delivery catheters 100 , 110 for deploying a third or P 3 anchor assembly 122 comprised of discrete, flat flexible anchor elements 124 coupled by a flexible tensile member, such as a suture 126 , and capable of being drawn together against opposite sides of annulus tissue 40 through the use of a slip knot or other lock member 128 .
- Anchor delivery catheters 100 , 110 , 120 may be separate catheters or may be the same catheter used to separately deliver the anchors or other fasteners or plicating elements. For ease of use, however, separate catheters that have been preloaded with separate anchors may be easiest to use in practice.
- Suitable pusher rods or elements 125 FIG.
- Anchor elements 104 , 114 , 124 may be formed from a material such as a surgical grade fabric material (e.g., a polyester material such as DacronTM) designed to promote tissue ingrowth so that the anchors 102 , 112 , 122 become essentially encased in tissue over time.
- a surgical grade fabric material e.g., a polyester material such as DacronTM
- any suitable anchor may be used.
- other suitable anchors are disclosed in U.S. patent application Ser. No. 11/174,951, filed Jul. 5, 2005, assigned to the assignee of the present invention and the disclosure of which is hereby incorporated by reference herein.
- FIGS. 16 and 16 A-D generally illustrate a cinching and locking procedure for plicating the mitral annulus tissue 40 .
- this can involve the use of an outer plication catheter 130 carrying a suture locker 132 at its distal end.
- An inner plication catheter 134 is received for sliding movement within the lumen of the outer plication catheter 130 .
- the distal end 134 a of the inner plication catheter 134 abuts a proximal portion of the suture locker 132 .
- the suture locker 132 includes a slidable pin 136 having ends that are received in respective slot portions 130 a , 130 b of outer plication catheter 130 at its distal end.
- the pin 136 is initially retained in an angled slot 130 b , and in an identical slot (not shown) on the diametrically opposite side of the outer plication catheter 134 , while the catheter assembly 130 , 134 is directed through the guide catheter 50 into the left ventricle 14 as shown in FIG. 16 .
- the inner catheter 134 provides an upward force against the suture locker 132 to bias the pin upwardly to the end of the angled slot 130 b as shown in FIG. 16A .
- the cinching or plicating process and locking process may begin.
- the outer plication catheter 130 is initially moved in a distal direction as shown by the arrow in FIG. 16B , relative to the inner plication catheter 134 , to force the pin 136 to ride downward in the angled slot 130 b such that it is aligned with the vertical slot 130 a and is pushed upwardly in the slots 138 , 140 ( FIG. 16D ). This tightens the pin against the respective sutures 106 , 116 , 126 as the suture locker travels toward the annulus tissue 40 .
- the plication catheters 130 , 134 may be withdrawn proximally through the guide catheter 50 .
- the suture locker 132 may include a spring-like member 142 for preventing proximal movement of the pin 136 after the desired amount of plication or tightening has been achieved.
- anchor elements 114 , 124 may also have one or more radiopaque markers 114 a , 124 a as discussed above relative to anchor elements 104 .
- the slip knot 108 or other lock member and/or other portions of the suture material described herein may have one or more radiopaque markers.
- FIG. 18 illustrates a plication assistance device 150 that may be used for tensioning the respective sutures 106 , 116 , 126 and moving the suture locker 132 as previously described in connection with FIGS. 16 , 16 A-D, and 17 .
- the plication assistance device 150 includes a support structure 152 which may take the form of a base plate 152 .
- Base plate 152 includes a longitudinally extending slot 152 a .
- a fixed carriage 154 is rigidly affixed to a distal end of the base plate 152 and a sliding carriage 156 is secured to a more proximal location of base plate 152 .
- sliding carriage 156 is affixed by a pin or other structure (not shown) so that it may slide along slot 152 a .
- sliding carriage 156 includes a longitudinally extending slot 156 a that is parallel to slot 152 a .
- Slot 156 a receives a slide lock 158 that may be rotated to respectively lock and unlock the sliding carriage 156 relative to the base plate 152 .
- the slide lock 158 may have a threaded member (not shown) that engages base plate 152 .
- the sliding carriage 156 may slide along slot 152 a as the slide lock 158 slides along slot 156 a .
- the slide lock 158 may then be tightened at the desired position to fix the sliding carriage 156 at a desired location along the base plate 152 .
- the carriages 154 , 156 also include respective catheter locks 160 , 162 that may be rotated to tighten and loosen the connections between respective catheter hubs 146 , 148 and carriages 154 , 156 .
- a proximal end portion of the base plate 152 includes suture tensioning mechanisms 164 , 166 , 168 for the respective sutures 106 , 116 , 126 . More specifically, these mechanisms include spools 170 , 172 , 174 for receiving proximal end portions of the respective sutures 106 , 116 , 126 which may be wrapped and firmly engaged with the spools 170 , 172 , 174 .
- the suture tensioning mechanisms 164 , 166 , 168 further comprise rotatable knobs 176 , 178 , 180 connected with respective right angle gear boxes 182 , 184 , 186 for converting rotation of the knobs 176 , 178 , 180 to rotation of the spools 170 , 172 , 174 . That is, an output of each gear box 182 , 184 , 186 is coupled to a respective one of the spools 170 , 172 , 174 . In this manner, each suture 106 , 116 , 126 may be separately pulled or tensioned by rotating the corresponding knob 176 , 178 , 180 .
- the inner and outer plication catheters 130 and 134 are respectively secured and locked into the carriages 154 and 156 , as shown in FIG. 18 , after the suture locker 132 has been moved approximately to the position as shown in FIG. 16 .
- the suture locker 132 is firmly held by the two catheters 130 , 134 as previously described and after the sliding carriage 156 is locked down onto the base plate 152 by tightening slide lock 158 .
- the sutures 106 , 116 , 126 are wrapped around their corresponding spools 170 , 172 , 174 and tensioned at a suitable minimum force.
- the tension at P 1 and P 3 may be in the range of 2-4 lbs, while the tension at P 2 (i.e., suture 106 ) may be in the range of 4-6 lbs.
- the tension at P 1 and P 3 is maintained high enough to sustain tissue plication, while the tension of P 2 is slightly higher so as to lock or activate the locker 132 after plication occurs. More specifically, the higher tension on P 2 suture 106 drives the pin 136 in the locker distally in the slot 138 relative to the body of the locker 132 . Stated another way, the body of the locker 132 moves slightly proximally as the pin 136 remains stationary and grips the sutures 106 , 116 , 126 .
- the plication assistance device 150 includes a tension gauge mechanism 188 for allowing the user to measure the tension of at least one of the sutures 106 , 116 , 126 .
- the tension gauge mechanism 188 is being used to measure the tension of P 2 suture 106 .
- this illustrative tension gauge mechanism 188 comprises a housing or other support 190 having a lever arm 192 pivotally mounted therein by way of a pivot 194 .
- One end of the lever arm 192 includes an element such as a roller 196 for engaging the suture 106 , while the opposite end includes a pin or other indicator 198 for indicating the level of tension being applied to the suture 106 .
- a graduated scale 200 is provided in connection with the indicator 198 to indicate the tension being applied to the suture 106 .
- an electronic indicator and digital readout may be used.
- the indicator or pin 198 moves within a slot 202 in the housing 190 to allow it to be observed by the user.
- a spring support member 203 is also secured rigidly to the housing 190 , for example, by a pin or fastener 204 , or is simply a part of the housing or support 190 , and does not allow pivotal movement of the spring support member 203 .
- An opposite end of the spring support member 203 includes a connection point, which may be a hole 205 , while an intermediate location on the lever arm 192 likewise includes a connection point, which may also be a hole 206 .
- a coil spring 207 is connected between these two connection points 205 , 206 and applies a force resistive to rotation of the lever arm 192 and upward movement of the indicator 198 .
- this system including the spring 207 , is designed such that an applied tension in the direction of the arrow 208 will force the lever arm 192 to rotate clockwise around the pivot 194 (arrow 209 ) against the force of the spring 207 thereby indicating a measured amount of tension through upward movement of the indicator or pin 198 along the graduated scale 200 .
- the scale 200 may be graduated in any suitable manner depending on the needs of the procedure. In the present case, for purposes of measuring the tension on P 2 suture 106 , the scale 200 may be graduated to indicate forces between about 4 lbs and about 6 lbs with the middle of the range being suitable for tensioning the P 2 suture 106 .
- This suture tension provides potential energy that moves the catheters 130 , 134 relative to each other and locks the suture locker 132 as previously described, after the sliding carriage 156 is unlocked by loosening slide lock 158 .
- the plication catheters 130 , 132 are then removed from the guide catheter 50 leaving the long proximal tails of the suture 106 , 116 , 126 extending out of the patient through the guide catheter 50 .
- a suture cutter 210 is threaded along the sutures 106 , 116 , 126 through the guide catheter 50 to the position generally shown in FIG. 19 .
- the suture cutter comprises an intermediate catheter portion 212 and a distal end portion comprising a cutting assembly 214 .
- the cutting assembly 214 generally comprises a blade housing 215 and a reciprocating guillotine-style blade 216 slidable mounted therein.
- the blade 216 includes a cutting edge 216 a as shown best in FIGS. 20A , 20 B and 20 C.
- the blade 216 is mounted for sliding, reciprocating movement within a slot 218 of blade housing 215 .
- the blade 216 includes an opening 220 through which the sutures 106 , 116 , 126 extend to cross the path of the blade 216 within the housing 215 .
- the blade further includes a connecting end 222 coupled to an actuating element 224 which may, for example, comprise a wire or other member in a lumen 212 a of catheter portion 212 .
- the actuating element 224 may be pulled in the direction of the arrow in FIG. 20A to move the blade 216 in a proximal direction. The user may accomplish this with a suitable handle or trigger assembly (not shown) coupled to actuator element 224 and located outside the patient.
- the blade housing 215 includes a first aperture 226 at its distal end and a second aperture 228 along a lateral side thereof opposite to the distal aperture 226 .
- the sutures 106 , 116 , 126 may extend into the blade housing 215 through aperture 226 , opening 220 of blade 216 and then through aperture 228 as shown in FIG. 20A .
- actuating element 224 may be pulled to move the blade 216 in a proximal direction such that the cutting edge 216 a crosses edge 218 a with or without a shearing action to cut the sutures 106 , 116 , 126 at points just proximal to suture locker 132 as generally shown in FIG. 21 .
- the cutting edge 216 a may have a double bevel configuration instead of the single bevel design shown.
- FIG. 22 The completed annuloplasty or plication procedure is shown in FIG. 22 with the posterior leaflet 24 having been moved in an anterior direction to provide better coaptation with the anterior leaflet 22 and generally moving the posterior wall 42 of the left ventricle 14 in the same anterior direction.
- FIGS. 23-25 illustrate three additional embodiments of anchor assemblies which are only representative of the many variations and substitutions that may be made with respect to the anchor assemblies described herein.
- FIG. 23 illustrates an anchor assembly 230 having a plurality of discrete, flat flexible anchor elements 232 coupled along a flexible tensile member such as suture 234 .
- these anchor elements 232 are coupled to the suture 234 such that the suture extends through points separated widthwise along the rectangular anchor elements 232 as opposed to lengthwise.
- one or more radiopaque markers 232 a may be used.
- FIG. 24 illustrates an alternative anchor assembly 236 having similar discrete, flat flexible anchor elements 238 coupled along a flexible tensile member 240 with some anchor elements 238 coupled in a lengthwise fashion and some coupled in a widthwise fashion to the suture 240 , as shown.
- FIG. 25 illustrates another alternative anchor assembly 242 comprised of discrete, flat flexible anchor elements 244 coupled for sliding movement along a flexible tensile member such as a suture 246 .
- the option of having differently sized anchor elements is shown as well as the option of having different spacing between coupling points on each anchor element 244 to create different effects, such as fabric bunching, etc. It will be appreciated that many other forms of anchor assemblies utilizing various shapes, sizes and forms of discrete elements coupled for sliding movement along a flexible tensile member may be used with various advantages.
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| US11/685,240 US20080228265A1 (en) | 2007-03-13 | 2007-03-13 | Tissue anchors, systems and methods, and devices |
| US11/685,241 US20080228266A1 (en) | 2007-03-13 | 2007-03-13 | Plication assistance devices and methods |
| US11/935,054 US8911461B2 (en) | 2007-03-13 | 2007-11-05 | Suture cutter and method of cutting suture |
| PCT/US2008/056620 WO2008112740A2 (fr) | 2007-03-13 | 2008-03-12 | Systèmes et procédés d'introduction d'éléments dans un tissu |
| US14/010,950 US9358111B2 (en) | 2007-03-13 | 2013-08-27 | Tissue anchors, systems and methods, and devices |
| US14/462,177 US9750608B2 (en) | 2007-03-13 | 2014-08-18 | Systems and methods for introducing elements into tissue |
| US15/144,182 US20160317304A1 (en) | 2007-03-13 | 2016-05-02 | Tissue anchors, systems and methods, and devices |
| US16/268,592 US11660190B2 (en) | 2007-03-13 | 2019-02-06 | Tissue anchors, systems and methods, and devices |
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| US11/685,241 US20080228266A1 (en) | 2007-03-13 | 2007-03-13 | Plication assistance devices and methods |
| US11/685,242 US8864822B2 (en) | 2003-12-23 | 2007-03-13 | Devices and methods for introducing elements into tissue |
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| US11/685,239 Active 2030-07-31 US8845723B2 (en) | 2007-03-13 | 2007-03-13 | Systems and methods for introducing elements into tissue |
| US11/685,240 Abandoned US20080228265A1 (en) | 2007-03-13 | 2007-03-13 | Tissue anchors, systems and methods, and devices |
| US14/010,950 Expired - Fee Related US9358111B2 (en) | 2007-03-13 | 2013-08-27 | Tissue anchors, systems and methods, and devices |
| US14/462,177 Expired - Fee Related US9750608B2 (en) | 2007-03-13 | 2014-08-18 | Systems and methods for introducing elements into tissue |
| US15/144,182 Abandoned US20160317304A1 (en) | 2007-03-13 | 2016-05-02 | Tissue anchors, systems and methods, and devices |
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| US11/685,239 Active 2030-07-31 US8845723B2 (en) | 2007-03-13 | 2007-03-13 | Systems and methods for introducing elements into tissue |
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| US14/010,950 Expired - Fee Related US9358111B2 (en) | 2007-03-13 | 2013-08-27 | Tissue anchors, systems and methods, and devices |
| US14/462,177 Expired - Fee Related US9750608B2 (en) | 2007-03-13 | 2014-08-18 | Systems and methods for introducing elements into tissue |
| US15/144,182 Abandoned US20160317304A1 (en) | 2007-03-13 | 2016-05-02 | Tissue anchors, systems and methods, and devices |
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| WO (1) | WO2008112740A2 (fr) |
Cited By (96)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040172046A1 (en) * | 2002-10-21 | 2004-09-02 | Hlavka Edwin J. | Method and apparatus for performing catheter-based annuloplasty using local plications |
| US20050119734A1 (en) * | 2002-10-21 | 2005-06-02 | Spence Paul A. | Tissue fastening systems and methods utilizing magnetic guidance |
| US20080228198A1 (en) * | 2007-03-13 | 2008-09-18 | Mitralign, Inc. | Suture cutter and method of cutting suture |
| US20080228165A1 (en) * | 2007-03-13 | 2008-09-18 | Mitralign, Inc. | Systems and methods for introducing elements into tissue |
| US20080228267A1 (en) * | 2003-12-23 | 2008-09-18 | Mitralign, Inc. | Devices and methods for introducing elements into tissue |
| US20090076547A1 (en) * | 2005-07-05 | 2009-03-19 | Mitralign, Inc. | Tissue anchor and anchoring system |
| US20100030328A1 (en) * | 2008-04-18 | 2010-02-04 | Medtronic, Inc. | Apparatus for Treating a Heart Valve, in Particular a Mitral Valve |
| US20100070028A1 (en) * | 2008-09-12 | 2010-03-18 | Mitralign, Inc. | Tissue plication device and method for its use |
| US20110011917A1 (en) * | 2008-12-31 | 2011-01-20 | Hansen Medical, Inc. | Methods, devices, and kits for treating valve prolapse |
| US20110208298A1 (en) * | 2010-02-24 | 2011-08-25 | Medtronic Ventor Technologies Ltd | Mitral Prosthesis and Methods for Implantation |
| US8142493B2 (en) | 2003-12-23 | 2012-03-27 | Mitralign, Inc. | Method of heart valve repair |
| EP2446831A2 (fr) | 2010-10-27 | 2012-05-02 | Mitralign, Inc. | Dispositif manuel pour le déploiement contrôlé d'un ancrage de tissus |
| EP2465568A1 (fr) | 2010-12-19 | 2012-06-20 | Mitralign, Inc. | Cathéter guide orientable doté d'une forme incurvée préformée |
| US8357195B2 (en) | 2010-04-15 | 2013-01-22 | Medtronic, Inc. | Catheter based annuloplasty system and method |
| US8454656B2 (en) | 2011-03-01 | 2013-06-04 | Medtronic Ventor Technologies Ltd. | Self-suturing anchors |
| US8469983B2 (en) * | 2007-09-20 | 2013-06-25 | Sentreheart, Inc. | Devices and methods for remote suture management |
| US8657872B2 (en) | 2010-07-19 | 2014-02-25 | Jacques Seguin | Cardiac valve repair system and methods of use |
| CN103705279A (zh) * | 2012-09-29 | 2014-04-09 | 米特拉利根公司 | 折叠锁输送系统及其使用方法 |
| US8721663B2 (en) | 1999-05-20 | 2014-05-13 | Sentreheart, Inc. | Methods and apparatus for transpericardial left atrial appendage closure |
| US8771297B2 (en) | 2007-03-30 | 2014-07-08 | Sentreheart, Inc. | Devices, systems, and methods for closing the left atrial appendage |
| US8790356B2 (en) | 2010-06-09 | 2014-07-29 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures, transfascial suture assemblies, and methods of transfascial suturing |
| US8790370B2 (en) | 2012-03-30 | 2014-07-29 | Depuy Mitek, Llc | Surgical filament assemblies |
| US8795298B2 (en) | 2008-10-10 | 2014-08-05 | Guided Delivery Systems Inc. | Tether tensioning devices and related methods |
| US8795297B2 (en) | 2003-10-09 | 2014-08-05 | Sentreheart, Inc. | Apparatus and method for the ligation of tissue |
| US8814905B2 (en) | 2010-11-23 | 2014-08-26 | Depuy Mitek, Llc | Surgical filament snare assemblies |
| US8814903B2 (en) | 2009-07-24 | 2014-08-26 | Depuy Mitek, Llc | Methods and devices for repairing meniscal tissue |
| US8821544B2 (en) | 2010-11-23 | 2014-09-02 | Depuy Mitek, Llc | Surgical filament snare assemblies |
| US8821543B2 (en) | 2010-12-23 | 2014-09-02 | Depuy Mitek, Llc | Adjustable anchor systems and methods |
| WO2014134183A1 (fr) | 2013-02-26 | 2014-09-04 | Mitralign, Inc. | Dispositif et procédés pour réparation percutanée de valve tricuspide |
| US8828053B2 (en) | 2009-07-24 | 2014-09-09 | Depuy Mitek, Llc | Methods and devices for repairing and anchoring damaged tissue |
| US20140276648A1 (en) * | 2013-03-14 | 2014-09-18 | Valtech Cardio, Ltd. | Guidewire feeder |
| WO2014152503A1 (fr) | 2013-03-15 | 2014-09-25 | Mitralign, Inc. | Cathéters de translation, systèmes et leurs procédés d'utilisation |
| US8894684B2 (en) | 2012-05-07 | 2014-11-25 | Medos International Sàrl | Systems, devices, and methods for securing tissue using a suture having one or more protrusions |
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| US9095331B2 (en) | 2010-12-23 | 2015-08-04 | Medos International Sàrl | Adjustable anchor systems and methods |
| US9119893B2 (en) | 2010-11-04 | 2015-09-01 | Linvatec Corporation | Method and apparatus for securing an object to bone, including the provision and use of a novel suture assembly for securing an object to bone |
| US9192373B2 (en) | 2012-12-27 | 2015-11-24 | Medos International Sàrl | Surgical constructs and methods for securing tissue |
| US9198664B2 (en) | 2009-04-01 | 2015-12-01 | Sentreheart, Inc. | Tissue ligation devices and controls therefor |
| US9307978B2 (en) | 2010-11-04 | 2016-04-12 | Linvatec Corporation | Method and apparatus for securing an object to bone, including the provision and use of a novel suture assembly for securing an object to bone |
| US9307977B2 (en) | 2010-11-04 | 2016-04-12 | Conmed Corporation | Method and apparatus for securing an object to bone, including the provision and use of a novel suture assembly for securing suture to bone |
| US9345567B2 (en) | 2012-05-07 | 2016-05-24 | Medos International Sàrl | Systems, devices, and methods for securing tissue using snare assemblies and soft anchors |
| US9358112B2 (en) | 2001-04-24 | 2016-06-07 | Mitralign, Inc. | Method and apparatus for catheter-based annuloplasty using local plications |
| US9408608B2 (en) | 2013-03-12 | 2016-08-09 | Sentreheart, Inc. | Tissue ligation devices and methods therefor |
| US9445898B2 (en) | 2011-03-01 | 2016-09-20 | Medtronic Ventor Technologies Ltd. | Mitral valve repair |
| US9451938B2 (en) | 2010-04-27 | 2016-09-27 | DePuy Synthes Products, Inc. | Insertion instrument for anchor assembly |
| US9474606B2 (en) | 2009-05-04 | 2016-10-25 | Valtech Cardio, Ltd. | Over-wire implant contraction methods |
| US9486281B2 (en) | 2010-04-13 | 2016-11-08 | Sentreheart, Inc. | Methods and devices for accessing and delivering devices to a heart |
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| US9522006B2 (en) | 2005-04-07 | 2016-12-20 | Sentreheart, Inc. | Apparatus and method for the ligation of tissue |
| US9526613B2 (en) | 2005-03-17 | 2016-12-27 | Valtech Cardio Ltd. | Mitral valve treatment techniques |
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| US10070857B2 (en) | 2013-08-31 | 2018-09-11 | Mitralign, Inc. | Devices and methods for locating and implanting tissue anchors at mitral valve commissure |
| US10130369B2 (en) | 2015-03-24 | 2018-11-20 | Sentreheart, Inc. | Tissue ligation devices and methods therefor |
| US10226339B2 (en) | 2012-01-31 | 2019-03-12 | Mitral Valve Technologies Sarl | Mitral valve docking devices, systems and methods |
| US10226330B2 (en) | 2013-08-14 | 2019-03-12 | Mitral Valve Technologies Sarl | Replacement heart valve apparatus and methods |
| JP2019508204A (ja) * | 2016-05-16 | 2019-03-28 | ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． | 内視鏡縫合および縫合不全引き締め修復装置 |
| US10258408B2 (en) | 2013-10-31 | 2019-04-16 | Sentreheart, Inc. | Devices and methods for left atrial appendage closure |
| US10292710B2 (en) | 2016-02-26 | 2019-05-21 | Sentreheart, Inc. | Devices and methods for left atrial appendage closure |
| US10376266B2 (en) | 2012-10-23 | 2019-08-13 | Valtech Cardio, Ltd. | Percutaneous tissue anchor techniques |
| US10470882B2 (en) | 2008-12-22 | 2019-11-12 | Valtech Cardio, Ltd. | Closure element for use with annuloplasty structure |
| US10588742B2 (en) | 2013-08-14 | 2020-03-17 | Mitral Valve Technologies Sarl | Coiled anchor for supporting prosthetic heart valve, prosthetic heart valve, and deployment device |
| US10792152B2 (en) | 2011-06-23 | 2020-10-06 | Valtech Cardio, Ltd. | Closed band for percutaneous annuloplasty |
| CN112773562A (zh) * | 2020-04-28 | 2021-05-11 | 北京领健医疗科技有限公司 | 带位置检测器的瓣膜修复系统 |
| EP3600072A4 (fr) * | 2017-03-31 | 2021-06-02 | NeoChord, Inc. | Réparation de valvule cardiaque minimalement invasive dans un coeur battant |
| US11026791B2 (en) | 2018-03-20 | 2021-06-08 | Medtronic Vascular, Inc. | Flexible canopy valve repair systems and methods of use |
| CN113993572A (zh) * | 2019-07-25 | 2022-01-28 | 创新心有限公司 | 用于在心脏瓣膜周围布置导丝的装置 |
| US11285003B2 (en) | 2018-03-20 | 2022-03-29 | Medtronic Vascular, Inc. | Prolapse prevention device and methods of use thereof |
| US11517425B2 (en) | 2019-07-25 | 2022-12-06 | Innovheart S.R.L. | Device for implanting a prosthesis for a heart valve and assembly procedure |
| US11660190B2 (en) | 2007-03-13 | 2023-05-30 | Edwards Lifesciences Corporation | Tissue anchors, systems and methods, and devices |
| US11672524B2 (en) | 2019-07-15 | 2023-06-13 | Ancora Heart, Inc. | Devices and methods for tether cutting |
| US11684473B2 (en) * | 2019-07-25 | 2023-06-27 | Innovheart S.R.L. | Device for arranging guidewires around a heart valve |
| US11890187B2 (en) | 2010-03-05 | 2024-02-06 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves |
| US12472061B2 (en) | 2019-06-07 | 2025-11-18 | Edwards Lifesciences Corporation | Systems, devices, and methods for treating heart valves |
Families Citing this family (157)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7883538B2 (en) | 2002-06-13 | 2011-02-08 | Guided Delivery Systems Inc. | Methods and devices for termination |
| US20060122633A1 (en) | 2002-06-13 | 2006-06-08 | John To | Methods and devices for termination |
| US8333777B2 (en) | 2005-04-22 | 2012-12-18 | Benvenue Medical, Inc. | Catheter-based tissue remodeling devices and methods |
| US7749249B2 (en) | 2006-02-21 | 2010-07-06 | Kardium Inc. | Method and device for closing holes in tissue |
| US8449605B2 (en) | 2006-06-28 | 2013-05-28 | Kardium Inc. | Method for anchoring a mitral valve |
| US7837610B2 (en) | 2006-08-02 | 2010-11-23 | Kardium Inc. | System for improving diastolic dysfunction |
| US11259924B2 (en) | 2006-12-05 | 2022-03-01 | Valtech Cardio Ltd. | Implantation of repair devices in the heart |
| US9974653B2 (en) | 2006-12-05 | 2018-05-22 | Valtech Cardio, Ltd. | Implantation of repair devices in the heart |
| US8197464B2 (en) * | 2007-10-19 | 2012-06-12 | Cordis Corporation | Deflecting guide catheter for use in a minimally invasive medical procedure for the treatment of mitral valve regurgitation |
| US20090105815A1 (en) * | 2007-10-19 | 2009-04-23 | Matthew Krever | Push-in retainer system for use in the direct plication annuloplasty treatment of mitral valve regurgitation |
| JP2011500221A (ja) * | 2007-10-19 | 2011-01-06 | ガイデッド デリバリー システムズ， インコーポレイテッド | テザー終結の装置 |
| US9131939B1 (en) | 2008-02-27 | 2015-09-15 | Mitralign, Inc. | Device for percutaneously delivering a cardiac implant through the application of direct actuation forces external to the body |
| US8382829B1 (en) | 2008-03-10 | 2013-02-26 | Mitralign, Inc. | Method to reduce mitral regurgitation by cinching the commissure of the mitral valve |
| US20090287304A1 (en) * | 2008-05-13 | 2009-11-19 | Kardium Inc. | Medical Device for Constricting Tissue or a Bodily Orifice, for example a mitral valve |
| US8292900B2 (en) * | 2008-06-10 | 2012-10-23 | Boston Scientific Scimed, Inc. | Side branch wiring assist sheath and methods |
| US9192472B2 (en) | 2008-06-16 | 2015-11-24 | Valtec Cardio, Ltd. | Annuloplasty devices and methods of delivery therefor |
| CA2735748C (fr) | 2008-09-04 | 2017-08-29 | Curaseal Inc. | Dispositif gonflable pour le traitement d'une fistule enterique |
| US8147542B2 (en) | 2008-12-22 | 2012-04-03 | Valtech Cardio, Ltd. | Adjustable repair chords and spool mechanism therefor |
| US10517719B2 (en) | 2008-12-22 | 2019-12-31 | Valtech Cardio, Ltd. | Implantation of repair devices in the heart |
| US12485010B2 (en) | 2009-05-07 | 2025-12-02 | Edwards Lifesciences Innovation (Israel) Ltd. | Multiple anchor delivery tool |
| KR101116867B1 (ko) * | 2009-08-28 | 2012-03-06 | 김준홍 | 관상정맥동과 삼천판막의 조직보호기구, 매듭 전달 기구 및 이들을 포함하는 승모판막 서클라지 시술용 장치 |
| US20120179184A1 (en) * | 2009-09-15 | 2012-07-12 | Boris Orlov | Heart valve remodeling |
| EP2482749B1 (fr) | 2009-10-01 | 2017-08-30 | Kardium Inc. | Kit de construction de tissu ou d'orifice corporel, par exemple de valvule mitrale |
| US9011520B2 (en) | 2009-10-29 | 2015-04-21 | Valtech Cardio, Ltd. | Tissue anchor for annuloplasty device |
| US9180007B2 (en) | 2009-10-29 | 2015-11-10 | Valtech Cardio, Ltd. | Apparatus and method for guide-wire based advancement of an adjustable implant |
| US10098737B2 (en) | 2009-10-29 | 2018-10-16 | Valtech Cardio, Ltd. | Tissue anchor for annuloplasty device |
| US8870950B2 (en) | 2009-12-08 | 2014-10-28 | Mitral Tech Ltd. | Rotation-based anchoring of an implant |
| US8475525B2 (en) | 2010-01-22 | 2013-07-02 | 4Tech Inc. | Tricuspid valve repair using tension |
| US9307980B2 (en) | 2010-01-22 | 2016-04-12 | 4Tech Inc. | Tricuspid valve repair using tension |
| US10058323B2 (en) | 2010-01-22 | 2018-08-28 | 4 Tech Inc. | Tricuspid valve repair using tension |
| US9050066B2 (en) | 2010-06-07 | 2015-06-09 | Kardium Inc. | Closing openings in anatomical tissue |
| US11653910B2 (en) | 2010-07-21 | 2023-05-23 | Cardiovalve Ltd. | Helical anchor implantation |
| US8940002B2 (en) | 2010-09-30 | 2015-01-27 | Kardium Inc. | Tissue anchor system |
| EP2654624B1 (fr) | 2010-12-23 | 2023-10-04 | Twelve, Inc. | Système de réparation et remplacement de valvule mitrale |
| US8974476B2 (en) * | 2011-03-23 | 2015-03-10 | St. Jude Medical Puerto Rico Llc | Vascular closure device with compaction tube suture cutting port and methods |
| US9072511B2 (en) | 2011-03-25 | 2015-07-07 | Kardium Inc. | Medical kit for constricting tissue or a bodily orifice, for example, a mitral valve |
| US9211116B2 (en) | 2011-06-16 | 2015-12-15 | Curaseal Inc. | Fistula treatment devices and related methods |
| EP2720623A4 (fr) | 2011-06-17 | 2015-04-22 | Curaseal Inc | Dispositifs et procédés de traitement de fistules |
| EP4623867A3 (fr) | 2011-06-21 | 2025-11-05 | Twelve, Inc. | Dispositifs de valvule cardiaque prothétique |
| EP3345573B1 (fr) | 2011-06-23 | 2020-01-29 | Valtech Cardio, Ltd. | Élément de fermeture à utiliser avec une structure d'annuloplastie |
| US9918840B2 (en) | 2011-06-23 | 2018-03-20 | Valtech Cardio, Ltd. | Closed band for percutaneous annuloplasty |
| US9655722B2 (en) | 2011-10-19 | 2017-05-23 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
| US9763780B2 (en) | 2011-10-19 | 2017-09-19 | Twelve, Inc. | Devices, systems and methods for heart valve replacement |
| AU2012325813A1 (en) | 2011-10-19 | 2014-04-03 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
| US9039757B2 (en) | 2011-10-19 | 2015-05-26 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
| AU2012325809B2 (en) | 2011-10-19 | 2016-01-21 | Twelve, Inc. | Devices, systems and methods for heart valve replacement |
| US11202704B2 (en) | 2011-10-19 | 2021-12-21 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
| US8858623B2 (en) | 2011-11-04 | 2014-10-14 | Valtech Cardio, Ltd. | Implant having multiple rotational assemblies |
| CN104203157B (zh) | 2011-12-12 | 2016-02-03 | 戴维·阿隆 | 心脏瓣膜修补器械 |
| CA2900930A1 (fr) * | 2012-02-13 | 2013-08-22 | Mitraspan, Inc. | Procede et appareil de reparation d'une valvule mitrale |
| US10076414B2 (en) | 2012-02-13 | 2018-09-18 | Mitraspan, Inc. | Method and apparatus for repairing a mitral valve |
| US9579198B2 (en) | 2012-03-01 | 2017-02-28 | Twelve, Inc. | Hydraulic delivery systems for prosthetic heart valve devices and associated methods |
| US9011515B2 (en) | 2012-04-19 | 2015-04-21 | Caisson Interventional, LLC | Heart valve assembly systems and methods |
| US9427315B2 (en) | 2012-04-19 | 2016-08-30 | Caisson Interventional, LLC | Valve replacement systems and methods |
| US10849755B2 (en) | 2012-09-14 | 2020-12-01 | Boston Scientific Scimed, Inc. | Mitral valve inversion prostheses |
| US10543088B2 (en) | 2012-09-14 | 2020-01-28 | Boston Scientific Scimed, Inc. | Mitral valve inversion prostheses |
| EP2943132B1 (fr) | 2013-01-09 | 2018-03-28 | 4Tech Inc. | Organes d'ancrage de tissu mou |
| US20150351906A1 (en) | 2013-01-24 | 2015-12-10 | Mitraltech Ltd. | Ventricularly-anchored prosthetic valves |
| CN105208978B (zh) | 2013-03-14 | 2016-12-07 | 4科技有限公司 | 具有系绳接口的支架 |
| CN105246431B (zh) | 2013-05-20 | 2018-04-06 | 托尔福公司 | 可植入心脏瓣膜装置、二尖瓣修复装置以及相关系统和方法 |
| CN105263423B (zh) | 2013-06-25 | 2018-08-03 | 北京泰德制药股份有限公司 | 通过对右心室进行矫形和大小调整进行的经皮瓣修复 |
| US10299793B2 (en) | 2013-10-23 | 2019-05-28 | Valtech Cardio, Ltd. | Anchor magazine |
| US9050188B2 (en) | 2013-10-23 | 2015-06-09 | Caisson Interventional, LLC | Methods and systems for heart valve therapy |
| US10022114B2 (en) | 2013-10-30 | 2018-07-17 | 4Tech Inc. | Percutaneous tether locking |
| US10052095B2 (en) | 2013-10-30 | 2018-08-21 | 4Tech Inc. | Multiple anchoring-point tension system |
| US9610162B2 (en) | 2013-12-26 | 2017-04-04 | Valtech Cardio, Ltd. | Implantation of flexible implant |
| WO2015112971A1 (fr) | 2014-01-27 | 2015-07-30 | Children's Medical Center Corporation | Dispositif d'assistance mécanique |
| US9974647B2 (en) | 2014-06-12 | 2018-05-22 | Caisson Interventional, LLC | Two stage anchor and mitral valve assembly |
| US9801720B2 (en) | 2014-06-19 | 2017-10-31 | 4Tech Inc. | Cardiac tissue cinching |
| US9180005B1 (en) | 2014-07-17 | 2015-11-10 | Millipede, Inc. | Adjustable endolumenal mitral valve ring |
| EP4066786B1 (fr) | 2014-07-30 | 2025-05-14 | Cardiovalve Ltd. | Prothèse valvulaire articulable |
| US10195030B2 (en) | 2014-10-14 | 2019-02-05 | Valtech Cardio, Ltd. | Leaflet-restraining techniques |
| US9750605B2 (en) | 2014-10-23 | 2017-09-05 | Caisson Interventional, LLC | Systems and methods for heart valve therapy |
| US9750607B2 (en) | 2014-10-23 | 2017-09-05 | Caisson Interventional, LLC | Systems and methods for heart valve therapy |
| WO2016085761A1 (fr) * | 2014-11-24 | 2016-06-02 | Boston Scientific Scimed, Inc. | Dispositifs de fermeture chirurgical comprenant un élément d'agrafage |
| JP6717820B2 (ja) | 2014-12-02 | 2020-07-08 | ４テック インコーポレイテッド | 偏心組織アンカー |
| CA3162308A1 (fr) | 2015-02-05 | 2016-08-11 | Cardiovalve Ltd. | Valvule prosthetique a chassis coulissants sur le plan axial |
| JP6735294B2 (ja) | 2015-02-13 | 2020-08-05 | ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． | インプラント可能な心臓弁装置 |
| US20160256269A1 (en) | 2015-03-05 | 2016-09-08 | Mitralign, Inc. | Devices for treating paravalvular leakage and methods use thereof |
| US10010315B2 (en) | 2015-03-18 | 2018-07-03 | Mitralign, Inc. | Tissue anchors and percutaneous tricuspid valve repair using a tissue anchor |
| CN104706389B (zh) * | 2015-03-26 | 2017-03-01 | 诺琅医疗科技（上海）有限公司 | 一种远端距离可调的分叉导管 |
| CA2982063C (fr) | 2015-04-30 | 2024-07-02 | Valtech Cardio Ltd | Technologies d'annuloplastie |
| CN107847323B (zh) | 2015-06-01 | 2020-04-24 | 爱德华兹生命科学公司 | 配置用于经皮递送的心脏瓣膜修复装置 |
| EP3337428B1 (fr) | 2015-08-21 | 2024-09-25 | Twelve Inc. | Dispositifs de réparation de valves mitrales |
| US10335275B2 (en) | 2015-09-29 | 2019-07-02 | Millipede, Inc. | Methods for delivery of heart valve devices using intravascular ultrasound imaging |
| CN108289737B (zh) | 2015-11-17 | 2020-03-31 | 魅尔皮德股份有限公司 | 用于使心脏瓣环重新定形的可植入装置和输送系统 |
| WO2017117370A2 (fr) | 2015-12-30 | 2017-07-06 | Mitralign, Inc. | Système et procédé de réduction de régurgitation tricuspide |
| CA3010324A1 (fr) | 2015-12-30 | 2017-07-06 | Caisson Interventional, LLC | Systemes et methodes pour therapie de valvule cardiaque |
| US10751182B2 (en) | 2015-12-30 | 2020-08-25 | Edwards Lifesciences Corporation | System and method for reshaping right heart |
| CN108778187A (zh) | 2015-12-30 | 2018-11-09 | 管道医疗技术股份有限公司 | 二尖瓣瓣叶拴系 |
| US10531866B2 (en) | 2016-02-16 | 2020-01-14 | Cardiovalve Ltd. | Techniques for providing a replacement valve and transseptal communication |
| US10357365B2 (en) * | 2016-03-07 | 2019-07-23 | Serca Biomedical, LLC | Annuloplasty repair devices, systems and methods |
| US20210212825A1 (en) * | 2016-03-08 | 2021-07-15 | Dura Llc | Transcatheter valve leaflet replacement device, delivery, guiding and fixation system and method for same |
| US10624743B2 (en) * | 2016-04-22 | 2020-04-21 | Edwards Lifesciences Corporation | Beating-heart mitral valve chordae replacement |
| EP3448316B1 (fr) | 2016-04-29 | 2023-03-29 | Medtronic Vascular Inc. | Dispositifs de valve cardiaque prothétiques avec fils d'ancrage |
| GB201611910D0 (en) | 2016-07-08 | 2016-08-24 | Valtech Cardio Ltd | Adjustable annuloplasty device with alternating peaks and troughs |
| GB201613219D0 (en) | 2016-08-01 | 2016-09-14 | Mitraltech Ltd | Minimally-invasive delivery systems |
| CA3031187A1 (fr) | 2016-08-10 | 2018-02-15 | Cardiovalve Ltd. | Valve prothetique avec cadres concentriques. |
| ES3041130T3 (en) * | 2016-12-20 | 2025-11-07 | Edwards Lifesciences Corp | Systems and mechanisms for deploying a docking device for a replacement heart valve |
| US12472062B2 (en) | 2016-12-30 | 2025-11-18 | Pipeline Medical Technologies, Inc. | Method and apparatus for mitral valve chord repair |
| US9877833B1 (en) | 2016-12-30 | 2018-01-30 | Pipeline Medical Technologies, Inc. | Method and apparatus for transvascular implantation of neo chordae tendinae |
| US11083580B2 (en) | 2016-12-30 | 2021-08-10 | Pipeline Medical Technologies, Inc. | Method of securing a leaflet anchor to a mitral valve leaflet |
| US10925731B2 (en) | 2016-12-30 | 2021-02-23 | Pipeline Medical Technologies, Inc. | Method and apparatus for transvascular implantation of neo chordae tendinae |
| WO2018148584A1 (fr) | 2017-02-10 | 2018-08-16 | Millipede, Inc. | Dispositif implantable et système de mise en place permettant de remodeler un anneau de valvule cardiaque |
| CN110730633B (zh) * | 2017-04-05 | 2023-01-20 | 欧普斯医疗疗法有限公司 | 经导管的瓣膜、锚固件、系绳的植入组件 |
| US10820992B2 (en) * | 2017-04-05 | 2020-11-03 | Opus Medical Therapies, LLC | Transcatheter atrial sealing skirt, anchor, and tether and methods of implantation |
| US11337685B2 (en) * | 2017-04-05 | 2022-05-24 | Opus Medical Therapies, LLC | Transcatheter anchoring assembly for a mitral valve, a mitral valve, and related methods |
| US11045627B2 (en) | 2017-04-18 | 2021-06-29 | Edwards Lifesciences Corporation | Catheter system with linear actuation control mechanism |
| US10702378B2 (en) | 2017-04-18 | 2020-07-07 | Twelve, Inc. | Prosthetic heart valve device and associated systems and methods |
| US10575950B2 (en) | 2017-04-18 | 2020-03-03 | Twelve, Inc. | Hydraulic systems for delivering prosthetic heart valve devices and associated methods |
| US10433961B2 (en) | 2017-04-18 | 2019-10-08 | Twelve, Inc. | Delivery systems with tethers for prosthetic heart valve devices and associated methods |
| US10792151B2 (en) | 2017-05-11 | 2020-10-06 | Twelve, Inc. | Delivery systems for delivering prosthetic heart valve devices and associated methods |
| US10646338B2 (en) | 2017-06-02 | 2020-05-12 | Twelve, Inc. | Delivery systems with telescoping capsules for deploying prosthetic heart valve devices and associated methods |
| US10709591B2 (en) | 2017-06-06 | 2020-07-14 | Twelve, Inc. | Crimping device and method for loading stents and prosthetic heart valves |
| EP3641699B1 (fr) * | 2017-06-19 | 2023-08-30 | Harpoon Medical, Inc. | Appareil pour interventions cardiaques |
| US10729541B2 (en) | 2017-07-06 | 2020-08-04 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
| US10786352B2 (en) | 2017-07-06 | 2020-09-29 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
| US11793633B2 (en) | 2017-08-03 | 2023-10-24 | Cardiovalve Ltd. | Prosthetic heart valve |
| US12064347B2 (en) | 2017-08-03 | 2024-08-20 | Cardiovalve Ltd. | Prosthetic heart valve |
| US12458493B2 (en) | 2017-09-19 | 2025-11-04 | Cardiovalve Ltd. | Prosthetic heart valve and delivery systems and methods |
| CN111386090B (zh) * | 2017-09-19 | 2022-05-17 | 波士顿科学国际有限公司 | 二尖瓣脱垂的经皮修复 |
| CR20200141A (es) * | 2017-10-24 | 2020-08-27 | Univ Maryland | Metodos y aparatos para procedimientos cardíacos |
| US10835221B2 (en) | 2017-11-02 | 2020-11-17 | Valtech Cardio, Ltd. | Implant-cinching devices and systems |
| US11135062B2 (en) | 2017-11-20 | 2021-10-05 | Valtech Cardio Ltd. | Cinching of dilated heart muscle |
| US20190175887A1 (en) * | 2017-12-13 | 2019-06-13 | Acclarent, Inc. | Dilation instrument with proximally located force sensor |
| CN111655200B (zh) | 2018-01-24 | 2023-07-14 | 爱德华兹生命科学创新(以色列)有限公司 | 瓣环成形术结构的收缩 |
| WO2019145941A1 (fr) | 2018-01-26 | 2019-08-01 | Valtech Cardio, Ltd. | Techniques pour faciliter la fixation de valve cardiaque et le remplacement de cordon |
| EP3527170B1 (fr) * | 2018-02-20 | 2020-11-18 | Institut National des Sciences Appliquées de Lyon | Dispositif pour aider un praticien dans le réglage de la longueur d'un cordage artificiel implanté dans une valvule cardiaque auriculo-ventriculaire |
| US11173030B2 (en) | 2018-05-09 | 2021-11-16 | Neochord, Inc. | Suture length adjustment for minimally invasive heart valve repair |
| US11224418B2 (en) * | 2018-06-15 | 2022-01-18 | Edwards Lifesciences Corporation | Papillary muscle approximation pads |
| US12121775B2 (en) | 2018-06-27 | 2024-10-22 | Dhiren Rajagopal | Brace for preventing finger injuries |
| MX2020013973A (es) | 2018-07-12 | 2021-06-15 | Valtech Cardio Ltd | Sistemas de anuloplastia y herramientas de bloqueo para ello. |
| WO2020096827A1 (fr) * | 2018-11-07 | 2020-05-14 | Neotract, Inc. | Système d'administration d'un marqueur de repère |
| JP2022513793A (ja) | 2018-12-12 | 2022-02-09 | パイプライン メディカル テクノロジーズ， インコーポレイテッド | 僧帽弁腱索修復のための方法及び装置 |
| EP3962417A4 (fr) | 2019-05-02 | 2023-01-18 | University of Maryland, Baltimore | Dispositif de translocation de valvule et méthode pour le traitement d'une régurgitation de valvule fonctionnelle |
| WO2020236750A1 (fr) | 2019-05-20 | 2020-11-26 | The Regents Of The University Of California | Système de distribution de dispositif médical percutané |
| CR20210575A (es) | 2019-05-29 | 2022-02-28 | Valtech Cardio Ltd | Sistemas y métodos de manejo de ancla de tejido |
| CA3140268A1 (fr) | 2019-06-10 | 2020-12-17 | Jude S. SAUER M.D. | Dispositif de tension de suture et procedes associes |
| US12364606B2 (en) | 2019-07-23 | 2025-07-22 | Edwards Lifesciences Innovation (Israel) Ltd. | Fluoroscopic visualization of heart valve anatomy |
| CN114258313A (zh) | 2019-08-28 | 2022-03-29 | 瓦尔泰克卡迪欧有限公司 | 低剖面可转向导管 |
| WO2021038559A1 (fr) | 2019-08-30 | 2021-03-04 | Valtech Cardio, Ltd. | Pointe de canal d'ancrage |
| JP2022551425A (ja) | 2019-09-25 | 2022-12-09 | カーディアック・インプランツ・エルエルシー | 心臓弁輪縮小システム |
| AU2020375903B2 (en) | 2019-10-29 | 2025-10-30 | Edwards Lifesciences Innovation (Israel) Ltd. | Annuloplasty and tissue anchor technologies |
| WO2021113173A1 (fr) * | 2019-12-06 | 2021-06-10 | Edwards Lifesciences Corporation | Tension et étiquetage de sutures chirurgicales |
| CN115243625A (zh) * | 2020-01-16 | 2022-10-25 | 尼奥绰德有限公司 | 用于微创心脏瓣膜修复的螺旋心脏锚固器 |
| US20230107886A1 (en) * | 2020-03-09 | 2023-04-06 | The Regents Of The University Of Michigan | Tie systems for sternal closure |
| EP4125623A1 (fr) * | 2020-03-27 | 2023-02-08 | Edwards Lifesciences Corporation | Distribution de tension de suture |
| WO2021236634A2 (fr) | 2020-05-20 | 2021-11-25 | Cardiac Implants, Llc | Réduction du diamètre d'un anneau valvulaire cardiaque avec commande indépendante sur chacun des ancrages qui sont lancés dans l'anneau |
| US12350155B2 (en) | 2020-06-17 | 2025-07-08 | Pipeline Medical Technologies, Inc. | Method and apparatus for mitral valve chord repair |
| WO2021255533A1 (fr) | 2020-06-19 | 2021-12-23 | Valtech Cardio Ltd. | Ancres pour tissu à arrêt automatique |
| US12357459B2 (en) | 2020-12-03 | 2025-07-15 | Cardiovalve Ltd. | Transluminal delivery system |
| US20240238093A1 (en) * | 2021-05-21 | 2024-07-18 | Shanghai Shape Memory Alloy Co., Ltd. | Ring contraction apparatus for mitral valve annulus |
| WO2022256198A1 (fr) * | 2021-06-02 | 2022-12-08 | Tendyne Holdings, Inc. | Ancrage extensible pour valvule mitrale prothétique |
| US20230102138A1 (en) * | 2021-09-29 | 2023-03-30 | Boston Scientific Scimed, Inc. | Medical device for cutting a suture during a minimally invasive procedure |
| WO2023086943A2 (fr) * | 2021-11-12 | 2023-05-19 | Xdot Medical Inc. | Systèmes et procédés de fermeture d'ouvertures de tissu |
| EP4629904A1 (fr) | 2022-12-06 | 2025-10-15 | Boston Scientific Scimed Inc. | Dispositif médical pour couper une suture lors d'une procédure minimalement invasive |
| SE2351228A1 (en) * | 2023-10-27 | 2025-04-28 | Rafael Martin Astudillo | Aortic dissection implant and aortic dissection system for remodelling and treating blood flow within a false lumen |
Citations (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2143910A (en) * | 1934-03-30 | 1939-01-17 | Davis & Geck Inc | Ribbon gut and method of using the same |
| US3674014A (en) * | 1969-10-28 | 1972-07-04 | Astra Meditec Ab | Magnetically guidable catheter-tip and method |
| US3794041A (en) * | 1971-11-30 | 1974-02-26 | Yeda Res & Dev | Gastrointestinal catheter |
| US3841521A (en) * | 1970-08-17 | 1974-10-15 | R Jarvik | Repeating ligature guns, multi-ligature cartridges and preformed ligatures therefor |
| US3986493A (en) * | 1975-07-28 | 1976-10-19 | Hendren Iii William Hardy | Electromagnetic bougienage method |
| US4042979A (en) * | 1976-07-12 | 1977-08-23 | Angell William W | Valvuloplasty ring and prosthetic method |
| US4055861A (en) * | 1975-04-11 | 1977-11-01 | Rhone-Poulenc Industries | Support for a natural human heart valve |
| US4369787A (en) * | 1978-09-26 | 1983-01-25 | Laschal Instruments Corp. | Method of cutting a suture |
| US4489446A (en) * | 1982-07-14 | 1984-12-25 | Reed Charles C | Heart valve prosthesis |
| US4532926A (en) * | 1983-06-20 | 1985-08-06 | Ethicon, Inc. | Two-piece tissue fastener with ratchet leg staple and sealable latching receiver |
| US4809713A (en) * | 1987-10-28 | 1989-03-07 | Joseph Grayzel | Catheter with magnetic fixation |
| US4917698A (en) * | 1988-12-22 | 1990-04-17 | Baxter International Inc. | Multi-segmented annuloplasty ring prosthesis |
| US4945912A (en) * | 1988-11-25 | 1990-08-07 | Sensor Electronics, Inc. | Catheter with radiofrequency heating applicator |
| US5016353A (en) * | 1986-02-19 | 1991-05-21 | American Safety Razor Company | Suture cutter |
| US5041129A (en) * | 1990-07-02 | 1991-08-20 | Acufex Microsurgical, Inc. | Slotted suture anchor and method of anchoring a suture |
| US5041130A (en) * | 1989-07-31 | 1991-08-20 | Baxter International Inc. | Flexible annuloplasty ring and holder |
| US5061277A (en) * | 1986-08-06 | 1991-10-29 | Baxter International Inc. | Flexible cardiac valvular support prosthesis |
| US5104407A (en) * | 1989-02-13 | 1992-04-14 | Baxter International Inc. | Selectively flexible annuloplasty ring |
| US5123914A (en) * | 1986-05-19 | 1992-06-23 | Cook Incorporated | Visceral anchor for visceral wall mobilization |
| US5171232A (en) * | 1989-06-13 | 1992-12-15 | Cordis Corporation | Catheter having highly radiopaque, flexible tip |
| US5192302A (en) * | 1989-12-04 | 1993-03-09 | Kensey Nash Corporation | Plug devices for sealing punctures and methods of use |
| US5201880A (en) * | 1992-01-27 | 1993-04-13 | Pioneering Technologies, Inc. | Mitral and tricuspid annuloplasty rings |
| US5203777A (en) * | 1992-03-19 | 1993-04-20 | Lee Peter Y | Radiopaque marker system for a tubular device |
| US5306234A (en) * | 1993-03-23 | 1994-04-26 | Johnson W Dudley | Method for closing an atrial appendage |
| US5306296A (en) * | 1992-08-21 | 1994-04-26 | Medtronic, Inc. | Annuloplasty and suture rings |
| US5337736A (en) * | 1992-09-30 | 1994-08-16 | Reddy Pratap K | Method of using a laparoscopic retractor |
| US5360444A (en) * | 1991-03-19 | 1994-11-01 | Kenji Kusuhara | Occluder supporter and a method of attachment thereof |
| US5364393A (en) * | 1990-07-02 | 1994-11-15 | Heart Technology, Inc. | Tissue dissipative recanalization catheter |
| US5429131A (en) * | 1994-02-25 | 1995-07-04 | The Regents Of The University Of California | Magnetized electrode tip catheter |
| US5450860A (en) * | 1993-08-31 | 1995-09-19 | W. L. Gore & Associates, Inc. | Device for tissue repair and method for employing same |
| US5452513A (en) * | 1994-06-29 | 1995-09-26 | Eric Hulsman | Suture cutter |
| US5464023A (en) * | 1994-01-31 | 1995-11-07 | Cordis Corporation | Magnetic exchange device for catheters |
| US5545178A (en) * | 1994-04-29 | 1996-08-13 | Kensey Nash Corporation | System for closing a percutaneous puncture formed by a trocar to prevent tissue at the puncture from herniating |
| US5571215A (en) * | 1993-02-22 | 1996-11-05 | Heartport, Inc. | Devices and methods for intracardiac procedures |
| US5593424A (en) * | 1994-08-10 | 1997-01-14 | Segmed, Inc. | Apparatus and method for reducing and stabilizing the circumference of a vascular structure |
| US5607471A (en) * | 1993-08-03 | 1997-03-04 | Jacques Seguin | Prosthetic ring for heart surgery |
| US5623943A (en) * | 1992-08-12 | 1997-04-29 | Scimed Life Systems, Inc. | Magnetic medical shaft movement control device and method |
| US5626590A (en) * | 1994-02-10 | 1997-05-06 | Wilk; Peter J. | Laparoscopic suturing technique and associated device |
| US5640955A (en) * | 1995-02-14 | 1997-06-24 | Daig Corporation | Guiding introducers for use in the treatment of accessory pathways around the mitral valve using a retrograde approach |
| US5669919A (en) * | 1996-08-16 | 1997-09-23 | Medtronic, Inc. | Annuloplasty system |
| US5674279A (en) * | 1992-01-27 | 1997-10-07 | Medtronic, Inc. | Annuloplasty and suture rings |
| US5682906A (en) * | 1993-02-22 | 1997-11-04 | Heartport, Inc. | Methods of performing intracardiac procedures on an arrested heart |
| US5690656A (en) * | 1995-06-27 | 1997-11-25 | Cook Incorporated | Method and apparatus for creating abdominal visceral anastomoses |
| US5706827A (en) * | 1994-09-21 | 1998-01-13 | Scimed Life Systems, Inc. | Magnetic lumen catheter |
| US5716399A (en) * | 1995-10-06 | 1998-02-10 | Cardiomend Llc | Methods of heart valve repair |
| US5716367A (en) * | 1995-10-18 | 1998-02-10 | Nissho Corporation | Catheter assembly for intracardiac suture |
| US5716397A (en) * | 1996-12-06 | 1998-02-10 | Medtronic, Inc. | Annuloplasty device with removable stiffening element |
| US5776080A (en) * | 1992-08-12 | 1998-07-07 | Scimed Life Systems, Inc. | Shaft movement control apparatus |
| US5776189A (en) * | 1997-03-05 | 1998-07-07 | Khalid; Naqeeb | Cardiac valvular support prosthesis |
| US5797939A (en) * | 1989-12-05 | 1998-08-25 | Yoon; Inbae | Endoscopic scissors with longitudinal operating channel |
| US5851185A (en) * | 1997-07-02 | 1998-12-22 | Cabot Technology Corporation | Apparatus for alignment of tubular organs |
| US5879366A (en) * | 1996-12-20 | 1999-03-09 | W.L. Gore & Associates, Inc. | Self-expanding defect closure device and method of making and using |
| US5967984A (en) * | 1995-06-30 | 1999-10-19 | Boston Scientific Corporation | Ultrasound imaging catheter with a cutting element |
| US6050472A (en) * | 1996-04-26 | 2000-04-18 | Olympus Optical Co., Ltd. | Surgical anastomosis stapler |
| US6113611A (en) * | 1998-05-28 | 2000-09-05 | Advanced Vascular Technologies, Llc | Surgical fastener and delivery system |
| USRE36974E (en) * | 1993-05-14 | 2000-11-28 | Bonutti; Peter M. | Suture anchor |
| US20020087178A1 (en) * | 2000-08-25 | 2002-07-04 | Nobles Anthony A. | Suture cutter |
| US20030078465A1 (en) * | 2001-10-16 | 2003-04-24 | Suresh Pai | Systems for heart treatment |
| US6561019B1 (en) * | 1997-04-04 | 2003-05-13 | Siemens Aktiengesellschaft | Method and apparatus for tensile testing a spliced connection of fibers in a fiber splicing device |
| US20030144697A1 (en) * | 2002-01-30 | 2003-07-31 | Cardiac Dimensions, Inc. | Fixed length anchor and pull mitral valve device and method |
| US20030220685A1 (en) * | 2001-04-24 | 2003-11-27 | Hlavka Edwin J. | Method and apparatus for catheter-based annuloplasty using local plications |
| US20040049211A1 (en) * | 2002-06-12 | 2004-03-11 | Mitral Interventions, Inc. | Method and apparatus for tissue connection |
| US20040122456A1 (en) * | 2002-12-11 | 2004-06-24 | Saadat Vahid C. | Methods and apparatus for gastric reduction |
| US20050119734A1 (en) * | 2002-10-21 | 2005-06-02 | Spence Paul A. | Tissue fastening systems and methods utilizing magnetic guidance |
| US20050125011A1 (en) * | 2001-04-24 | 2005-06-09 | Spence Paul A. | Tissue fastening systems and methods utilizing magnetic guidance |
| US20050177228A1 (en) * | 2003-12-16 | 2005-08-11 | Solem Jan O. | Device for changing the shape of the mitral annulus |
| US6949122B2 (en) * | 2001-11-01 | 2005-09-27 | Cardiac Dimensions, Inc. | Focused compression mitral valve device and method |
| US20050251208A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Linear anchors for anchoring to tissue |
| US20050267533A1 (en) * | 2004-03-23 | 2005-12-01 | Michael Gertner | Methods and devices for the surgical creation of satiety and biofeedback pathways |
| US20050267571A1 (en) * | 2003-12-23 | 2005-12-01 | Spence Paul A | Tissue fastening systems and methods utilizing magnetic guidance |
| US20050283192A1 (en) * | 1999-12-02 | 2005-12-22 | Torrie Paul A | Closure device and method for tissue repair |
| US20050288694A1 (en) * | 2004-06-23 | 2005-12-29 | Stepehen Solomon | Adjustable percutaneous stomach lumen restriction device |
| US20060009784A1 (en) * | 2004-07-07 | 2006-01-12 | Percutaneous Systems, Inc. | Methods and apparatus for deploying conformed structures in body lumens |
| US7004958B2 (en) * | 2002-03-06 | 2006-02-28 | Cardiac Dimensions, Inc. | Transvenous staples, assembly and method for mitral valve repair |
| US20060069429A1 (en) * | 2001-04-24 | 2006-03-30 | Spence Paul A | Tissue fastening systems and methods utilizing magnetic guidance |
| US7037334B1 (en) * | 2001-04-24 | 2006-05-02 | Mitralign, Inc. | Method and apparatus for catheter-based annuloplasty using local plications |
| US20060212045A1 (en) * | 2005-03-08 | 2006-09-21 | Peter Schilling | Surgical suture cutter |
| US20070010857A1 (en) * | 2005-07-05 | 2007-01-11 | Mitralign, Inc. | Tissue anchor, anchoring system and methods of using the same |
| US20070106310A1 (en) * | 2005-11-10 | 2007-05-10 | Goldin Mark A | Suture cutter |
| US20080228198A1 (en) * | 2007-03-13 | 2008-09-18 | Mitralign, Inc. | Suture cutter and method of cutting suture |
| US20080228267A1 (en) * | 2003-12-23 | 2008-09-18 | Mitralign, Inc. | Devices and methods for introducing elements into tissue |
| US20080228266A1 (en) * | 2007-03-13 | 2008-09-18 | Mitralign, Inc. | Plication assistance devices and methods |
Family Cites Families (197)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL129495C (fr) * | 1963-08-03 | |||
| US3328876A (en) | 1964-10-27 | 1967-07-04 | Clemens B Hoppe | Surgical suture extractor |
| US3959960A (en) | 1975-03-12 | 1976-06-01 | Santos Manuel V | Tensioning, twisting and cutting device for sutures |
| US3995619A (en) | 1975-10-14 | 1976-12-07 | Glatzer Stephen G | Combination subcutaneous suture remover, biopsy sampler and syringe |
| US4258705A (en) | 1978-09-15 | 1981-03-31 | Coloplast A/S | Magnetic system for use in sealing body openings |
| US6764500B1 (en) | 1989-05-29 | 2004-07-20 | Kensey Nash Corporation | Sealing device |
| US5984939A (en) | 1989-12-05 | 1999-11-16 | Yoon; Inbae | Multifunctional grasping instrument with cutting member and operating channel for use in endoscopic and non-endoscopic procedures |
| US5171259A (en) | 1990-04-02 | 1992-12-15 | Kanji Inoue | Device for nonoperatively occluding a defect |
| US5304190A (en) | 1992-05-08 | 1994-04-19 | Ethicon, Inc. | Endoscopic cutting apparatus |
| DE4240533C1 (de) | 1992-11-27 | 1994-04-07 | Ethicon Gmbh | Endoskopische Schlinge mit Applizierinstrument |
| US5797960A (en) | 1993-02-22 | 1998-08-25 | Stevens; John H. | Method and apparatus for thoracoscopic intracardiac procedures |
| US5364365A (en) | 1993-08-30 | 1994-11-15 | Surgin Surgical Instrumentation, Inc. | Safety device for laparoscopic instruments |
| US5540718A (en) | 1993-09-20 | 1996-07-30 | Bartlett; Edwin C. | Apparatus and method for anchoring sutures |
| US5673695A (en) * | 1995-08-02 | 1997-10-07 | Ep Technologies, Inc. | Methods for locating and ablating accessory pathways in the heart |
| US5656028A (en) * | 1993-11-03 | 1997-08-12 | Daig Corporation | Process for the nonsurgical mapping and/or treatment of ectopic atrial tachycardia using a guiding introducer |
| DE4406203A1 (de) | 1994-02-25 | 1995-08-31 | Basim A Dr Fleega | Besteck zum Durchführen einer operativen transarthroskopischen Rekonstruktion eines Rotatoren-Manschettenrisses |
| US5531759A (en) * | 1994-04-29 | 1996-07-02 | Kensey Nash Corporation | System for closing a percutaneous puncture formed by a trocar to prevent tissue at the puncture from herniating |
| US5997560A (en) | 1994-07-21 | 1999-12-07 | Sdgi Holdings, Inc. | Surgical cutting instrument |
| US5593435A (en) * | 1994-07-29 | 1997-01-14 | Baxter International Inc. | Distensible annuloplasty ring for surgical remodelling of an atrioventricular valve and nonsurgical method for post-implantation distension thereof to accommodate patient growth |
| US5527332A (en) | 1994-11-02 | 1996-06-18 | Mectra Labs, Inc. | Tissue cutter for surgery |
| US5814029A (en) * | 1994-11-03 | 1998-09-29 | Daig Corporation | Guiding introducer system for use in ablation and mapping procedures in the left ventricle |
| US6540755B2 (en) | 1995-02-14 | 2003-04-01 | Daig Corporation | Guiding introducers for use in the treatment of accessory pathways around the mitral valve using a retrograde approach |
| US5713907A (en) * | 1995-07-20 | 1998-02-03 | Endotex Interventional Systems, Inc. | Apparatus and method for dilating a lumen and for inserting an intraluminal graft |
| US5824005A (en) | 1995-08-22 | 1998-10-20 | Board Of Regents, The University Of Texas System | Maneuverable electrophysiology catheter for percutaneous or intraoperative ablation of cardiac arrhythmias |
| US6068637A (en) | 1995-10-03 | 2000-05-30 | Cedar Sinai Medical Center | Method and devices for performing vascular anastomosis |
| IL124038A (en) | 1995-10-13 | 2004-02-19 | Transvascular Inc | Apparatus for bypassing arterial obstructions and/or performing other transvascular procedures |
| IL124037A (en) | 1995-10-13 | 2003-01-12 | Transvascular Inc | Device and system for interstitial transvascular intervention |
| EP0871417B1 (fr) | 1995-12-01 | 2003-10-01 | Medtronic, Inc. | Prothese pour annuloplastie |
| US5813996A (en) | 1995-12-21 | 1998-09-29 | Scimed Life Systems, Inc. | Guide wire extension system with magnetic coupling |
| WO1997029709A1 (fr) | 1996-02-15 | 1997-08-21 | Biosense, Inc. | Interventions medicales et dispositif mettant en application des sondes intra-corporelles |
| US5830224A (en) | 1996-03-15 | 1998-11-03 | Beth Israel Deaconess Medical Center | Catheter apparatus and methodology for generating a fistula on-demand between closely associated blood vessels at a pre-chosen anatomic site in-vivo |
| US5662681A (en) * | 1996-04-23 | 1997-09-02 | Kensey Nash Corporation | Self locking closure for sealing percutaneous punctures |
| US5904147A (en) * | 1996-08-16 | 1999-05-18 | University Of Massachusetts | Intravascular catheter and method of controlling hemorrhage during minimally invasive surgery |
| US6042581A (en) * | 1996-11-08 | 2000-03-28 | Thomas J. Fogarty | Transvascular TMR device and method |
| US5911720A (en) | 1996-11-26 | 1999-06-15 | Ep Technologies, Inc. | Ablation catheter with segmented tip |
| US6050936A (en) | 1997-01-02 | 2000-04-18 | Myocor, Inc. | Heart wall tension reduction apparatus |
| US6077214A (en) | 1998-07-29 | 2000-06-20 | Myocor, Inc. | Stress reduction apparatus and method |
| US6045497A (en) | 1997-01-02 | 2000-04-04 | Myocor, Inc. | Heart wall tension reduction apparatus and method |
| US6406420B1 (en) * | 1997-01-02 | 2002-06-18 | Myocor, Inc. | Methods and devices for improving cardiac function in hearts |
| US5928224A (en) | 1997-01-24 | 1999-07-27 | Hearten Medical, Inc. | Device for the treatment of damaged heart valve leaflets and methods of using the device |
| AU8265598A (en) * | 1997-06-27 | 1999-01-19 | Trustees Of Columbia University In The City Of New York, The | Method and apparatus for circulatory valve repair |
| US6565562B1 (en) * | 1997-06-27 | 2003-05-20 | Baylis Medical Company Inc. | Method for the radio frequency perforation and the enlargement of a body tissue |
| US6071292A (en) | 1997-06-28 | 2000-06-06 | Transvascular, Inc. | Transluminal methods and devices for closing, forming attachments to, and/or forming anastomotic junctions in, luminal anatomical structures |
| US6159234A (en) | 1997-08-01 | 2000-12-12 | Peter M. Bonutti | Method and apparatus for securing a suture |
| US6015414A (en) * | 1997-08-29 | 2000-01-18 | Stereotaxis, Inc. | Method and apparatus for magnetically controlling motion direction of a mechanically pushed catheter |
| FR2768324B1 (fr) | 1997-09-12 | 1999-12-10 | Jacques Seguin | Instrument chirurgical permettant, par voie percutanee, de fixer l'une a l'autre deux zones de tissu mou, normalement mutuellement distantes |
| US6027514A (en) | 1997-12-17 | 2000-02-22 | Fox Hollow Technologies, Inc. | Apparatus and method for removing occluding material from body lumens |
| US6332893B1 (en) | 1997-12-17 | 2001-12-25 | Myocor, Inc. | Valve to myocardium tension members device and method |
| US5980515A (en) | 1997-12-19 | 1999-11-09 | Irvine Biomedical, Inc. | Devices and methods for lead extraction |
| US6530952B2 (en) * | 1997-12-29 | 2003-03-11 | The Cleveland Clinic Foundation | Bioprosthetic cardiovascular valve system |
| US6626919B1 (en) | 1997-12-29 | 2003-09-30 | Lee L. Swanstrom | Method and apparatus for attaching or locking an implant to an anatomic vessel or hollow organ wall |
| US6068648A (en) | 1998-01-26 | 2000-05-30 | Orthodyne, Inc. | Tissue anchoring system and method |
| US5944738A (en) * | 1998-02-06 | 1999-08-31 | Aga Medical Corporation | Percutaneous catheter directed constricting occlusion device |
| US6352543B1 (en) * | 2000-04-29 | 2002-03-05 | Ventrica, Inc. | Methods for forming anastomoses using magnetic force |
| US6197017B1 (en) * | 1998-02-24 | 2001-03-06 | Brock Rogers Surgical, Inc. | Articulated apparatus for telemanipulator system |
| WO2002051329A1 (fr) | 2000-12-21 | 2002-07-04 | Endovia Medical Inc | Segments articules commandes par un tendon, destines a un systeme de telemanipulateur |
| US7214230B2 (en) | 1998-02-24 | 2007-05-08 | Hansen Medical, Inc. | Flexible instrument |
| IL138666A0 (en) * | 1998-03-31 | 2001-10-31 | Transvascular Inc | Catheters, systems and methods for percutaneous in situ arterio-venous bypass |
| US6099460A (en) | 1998-04-28 | 2000-08-08 | Denker; Stephen | Electromagnetic heart assist technique and apparatus |
| US6173199B1 (en) * | 1998-05-05 | 2001-01-09 | Syncro Medical Innovations, Inc. | Method and apparatus for intubation of a patient |
| WO1999060370A2 (fr) * | 1998-05-15 | 1999-11-25 | Robin Medical, Inc. | Procede et dispositif servant a generer un couple commande dans des objets, en particulier, des objets a l'interieur d'un corps vivant |
| US6285903B1 (en) | 1998-06-30 | 2001-09-04 | Eclipse Surgical Technologies, Inc. | Intracorporeal device with radiopaque marker |
| US6165183A (en) | 1998-07-15 | 2000-12-26 | St. Jude Medical, Inc. | Mitral and tricuspid valve repair |
| US6669707B1 (en) | 1998-07-21 | 2003-12-30 | Lee L. Swanstrom | Method and apparatus for attaching or locking an implant to an anatomic vessel or hollow organ wall |
| US6260552B1 (en) | 1998-07-29 | 2001-07-17 | Myocor, Inc. | Transventricular implant tools and devices |
| AU4644799A (en) | 1998-08-02 | 2000-03-14 | Super Dimension Ltd. | Intrabody navigation system for medical applications |
| US6267781B1 (en) * | 1998-08-31 | 2001-07-31 | Quantum Therapeutics Corp. | Medical device and methods for treating valvular annulus |
| US6385472B1 (en) * | 1999-09-10 | 2002-05-07 | Stereotaxis, Inc. | Magnetically navigable telescoping catheter and method of navigating telescoping catheter |
| US6264668B1 (en) | 1998-09-16 | 2001-07-24 | Arnold S. Prywes | Ophthalmologic instrument for producing a fistula in the sclera |
| US6248112B1 (en) | 1998-09-30 | 2001-06-19 | C. R. Bard, Inc. | Implant delivery system |
| US6102945A (en) | 1998-10-16 | 2000-08-15 | Sulzer Carbomedics, Inc. | Separable annuloplasty ring |
| ATE324072T1 (de) | 1998-12-30 | 2006-05-15 | Ethicon Inc | Fadensicherungsgerät |
| US7563267B2 (en) | 1999-04-09 | 2009-07-21 | Evalve, Inc. | Fixation device and methods for engaging tissue |
| US6752813B2 (en) | 1999-04-09 | 2004-06-22 | Evalve, Inc. | Methods and devices for capturing and fixing leaflets in valve repair |
| DE60045096D1 (de) * | 1999-04-09 | 2010-11-25 | Evalve Inc | Verfahren und vorrichtung zur herzklappenreperation |
| DE60029234T2 (de) | 1999-05-10 | 2007-05-31 | Hansen Medical, Inc., Mountain View | Chirurgisches Instrument |
| US6292678B1 (en) | 1999-05-13 | 2001-09-18 | Stereotaxis, Inc. | Method of magnetically navigating medical devices with magnetic fields and gradients, and medical devices adapted therefor |
| US6126647A (en) | 1999-05-17 | 2000-10-03 | Hermetic Switch, Inc. | Magnetically guided catheter with sensor |
| US6790229B1 (en) | 1999-05-25 | 2004-09-14 | Eric Berreklouw | Fixing device, in particular for fixing to vascular wall tissue |
| US7416554B2 (en) * | 2002-12-11 | 2008-08-26 | Usgi Medical Inc | Apparatus and methods for forming and securing gastrointestinal tissue folds |
| ATE470414T1 (de) | 1999-06-25 | 2010-06-15 | Vahid Saadat | Gerät zur gewebebehandlung |
| US6626899B2 (en) | 1999-06-25 | 2003-09-30 | Nidus Medical, Llc | Apparatus and methods for treating tissue |
| US7955340B2 (en) | 1999-06-25 | 2011-06-07 | Usgi Medical, Inc. | Apparatus and methods for forming and securing gastrointestinal tissue folds |
| SE514718C2 (sv) | 1999-06-29 | 2001-04-09 | Jan Otto Solem | Anordning för behandling av bristande tillslutningsförmåga hos mitralisklaffapparaten |
| US7192442B2 (en) * | 1999-06-30 | 2007-03-20 | Edwards Lifesciences Ag | Method and device for treatment of mitral insufficiency |
| US6596014B2 (en) * | 1999-07-13 | 2003-07-22 | Scion Cardio-Vascular, Inc. | Suture with toggle and method of manufacture therefor |
| US6206895B1 (en) | 1999-07-13 | 2001-03-27 | Scion Cardio-Vascular, Inc. | Suture with toggle and delivery system |
| US6554852B1 (en) | 1999-08-25 | 2003-04-29 | Michael A. Oberlander | Multi-anchor suture |
| US6231561B1 (en) | 1999-09-20 | 2001-05-15 | Appriva Medical, Inc. | Method and apparatus for closing a body lumen |
| AU3885801A (en) | 1999-09-20 | 2001-04-24 | Stereotaxis, Inc. | Magnetically guided myocardial treatment system |
| US6964674B1 (en) | 1999-09-20 | 2005-11-15 | Nuvasive, Inc. | Annulotomy closure device |
| US6298257B1 (en) | 1999-09-22 | 2001-10-02 | Sterotaxis, Inc. | Cardiac methods and system |
| US6306133B1 (en) | 1999-10-02 | 2001-10-23 | Quantum Cor Incorporated | Ablation catheter system and methods for repairing a valvular annulus |
| FR2799364B1 (fr) | 1999-10-12 | 2001-11-23 | Jacques Seguin | Dispositif d'annuloplastie utilisable par voie mini-invasive |
| US6312447B1 (en) | 1999-10-13 | 2001-11-06 | The General Hospital Corporation | Devices and methods for percutaneous mitral valve repair |
| US6626930B1 (en) | 1999-10-21 | 2003-09-30 | Edwards Lifesciences Corporation | Minimally invasive mitral valve repair method and apparatus |
| US6623579B1 (en) * | 1999-11-02 | 2003-09-23 | Alien Technology Corporation | Methods and apparatus for fluidic self assembly |
| US6387104B1 (en) * | 1999-11-12 | 2002-05-14 | Scimed Life Systems, Inc. | Method and apparatus for endoscopic repair of the lower esophageal sphincter |
| US20020128708A1 (en) | 1999-12-09 | 2002-09-12 | Northrup William F. | Annuloplasty system |
| CN1243520C (zh) | 2000-01-14 | 2006-03-01 | 维亚科公司 | 组织瓣环成形术带 |
| US6402781B1 (en) * | 2000-01-31 | 2002-06-11 | Mitralife | Percutaneous mitral annuloplasty and cardiac reinforcement |
| US6537198B1 (en) | 2000-03-21 | 2003-03-25 | Myocor, Inc. | Splint assembly for improving cardiac function in hearts, and method for implanting the splint assembly |
| US20020072758A1 (en) * | 2000-12-13 | 2002-06-13 | Reo Michael L. | Processes for producing anastomotic components having magnetic properties |
| DE60134739D1 (de) | 2000-05-16 | 2008-08-21 | Atrionix Inc | Katheter mit lenkbarer spitze und spurausrichtungsmechanismus eines führungsdrahts |
| US6589208B2 (en) * | 2000-06-20 | 2003-07-08 | Applied Medical Resources Corporation | Self-deploying catheter assembly |
| US6840246B2 (en) | 2000-06-20 | 2005-01-11 | University Of Maryland, Baltimore | Apparatuses and methods for performing minimally invasive diagnostic and surgical procedures inside of a beating heart |
| ATE381291T1 (de) | 2000-06-23 | 2008-01-15 | Viacor Inc | Automatische ringförmige faltung zur mitralklappenreparatur |
| EP1401358B1 (fr) | 2000-06-30 | 2016-08-17 | Medtronic, Inc. | Appareil permettant d'effectuer une intervention sur une valvule cardiaque |
| US6419696B1 (en) | 2000-07-06 | 2002-07-16 | Paul A. Spence | Annuloplasty devices and related heart valve repair methods |
| US6773443B2 (en) | 2000-07-31 | 2004-08-10 | Regents Of The University Of Minnesota | Method and apparatus for taking a biopsy |
| US6524303B1 (en) | 2000-09-08 | 2003-02-25 | Stereotaxis, Inc. | Variable stiffness magnetic catheter |
| US8956407B2 (en) * | 2000-09-20 | 2015-02-17 | Mvrx, Inc. | Methods for reshaping a heart valve annulus using a tensioning implant |
| US6616684B1 (en) | 2000-10-06 | 2003-09-09 | Myocor, Inc. | Endovascular splinting devices and methods |
| US6723038B1 (en) | 2000-10-06 | 2004-04-20 | Myocor, Inc. | Methods and devices for improving mitral valve function |
| US6918917B1 (en) | 2000-10-10 | 2005-07-19 | Medtronic, Inc. | Minimally invasive annuloplasty procedure and apparatus |
| US6913608B2 (en) * | 2000-10-23 | 2005-07-05 | Viacor, Inc. | Automated annular plication for mitral valve repair |
| US7591826B2 (en) | 2000-12-28 | 2009-09-22 | Cardiac Dimensions, Inc. | Device implantable in the coronary sinus to provide mitral valve therapy |
| AU2002236790B2 (en) * | 2001-01-19 | 2006-08-17 | Boston Scientific Limited | Introducer for deployment of branched prosthesis |
| US6810882B2 (en) | 2001-01-30 | 2004-11-02 | Ev3 Santa Rosa, Inc. | Transluminal mitral annuloplasty |
| US6500184B1 (en) | 2001-01-31 | 2002-12-31 | Yung C. Chan | Suturing apparatus and method of suturing |
| US7235086B2 (en) | 2001-02-02 | 2007-06-26 | Lsi Solutions, Inc. | Crimping instrument with motion limiting feature |
| EP1363559A4 (fr) | 2001-02-05 | 2008-10-01 | Viacor Inc | Appareil et procede permettant de diminuer la regurgitation mitrale |
| CA2437387A1 (fr) | 2001-02-05 | 2002-08-15 | Viacor, Inc. | Procede et appareil destines a ameliorer la fonction de la valve mitrale |
| US20020107531A1 (en) | 2001-02-06 | 2002-08-08 | Schreck Stefan G. | Method and system for tissue repair using dual catheters |
| AU2002327224A1 (en) | 2001-03-05 | 2002-12-09 | Viacor, Incorporated | Apparatus and method for reducing mitral regurgitation |
| ES2298357T3 (es) | 2001-03-14 | 2008-05-16 | E.V.R. Endovascular Researches S.A. | Portador de hilo guia de cateter vascular. |
| WO2002076284A2 (fr) | 2001-03-23 | 2002-10-03 | Viacor, Inc. | Procede et dispositif destines a reduire la regurgitation mitrale |
| US7186264B2 (en) | 2001-03-29 | 2007-03-06 | Viacor, Inc. | Method and apparatus for improving mitral valve function |
| US7311731B2 (en) | 2001-04-27 | 2007-12-25 | Richard C. Satterfield | Prevention of myocardial infarction induced ventricular expansion and remodeling |
| US20020188170A1 (en) | 2001-04-27 | 2002-12-12 | Santamore William P. | Prevention of myocardial infarction induced ventricular expansion and remodeling |
| US6800090B2 (en) | 2001-05-14 | 2004-10-05 | Cardiac Dimensions, Inc. | Mitral valve therapy device, system and method |
| US6676702B2 (en) * | 2001-05-14 | 2004-01-13 | Cardiac Dimensions, Inc. | Mitral valve therapy assembly and method |
| US7544206B2 (en) * | 2001-06-29 | 2009-06-09 | Medtronic, Inc. | Method and apparatus for resecting and replacing an aortic valve |
| WO2003007796A2 (fr) | 2001-07-18 | 2003-01-30 | Ndo Surgical, Inc. | Methodes et dispositifs permettant de reconfigurer un tissu |
| US6892087B2 (en) * | 2001-11-01 | 2005-05-10 | Oscor Inc. | Vascular introducer with mapping capabilities |
| US20030078654A1 (en) | 2001-08-14 | 2003-04-24 | Taylor Daniel C. | Method and apparatus for improving mitral valve function |
| US7125421B2 (en) * | 2001-08-31 | 2006-10-24 | Mitral Interventions, Inc. | Method and apparatus for valve repair |
| US7052487B2 (en) | 2001-10-26 | 2006-05-30 | Cohn William E | Method and apparatus for reducing mitral regurgitation |
| US6824562B2 (en) | 2002-05-08 | 2004-11-30 | Cardiac Dimensions, Inc. | Body lumen device anchor, device and assembly |
| US6575971B2 (en) * | 2001-11-15 | 2003-06-10 | Quantum Cor, Inc. | Cardiac valve leaflet stapler device and methods thereof |
| US6719765B2 (en) | 2001-12-03 | 2004-04-13 | Bonutti 2003 Trust-A | Magnetic suturing system and method |
| US6793673B2 (en) | 2002-12-26 | 2004-09-21 | Cardiac Dimensions, Inc. | System and method to effect mitral valve annulus of a heart |
| US6908478B2 (en) * | 2001-12-05 | 2005-06-21 | Cardiac Dimensions, Inc. | Anchor and pull mitral valve device and method |
| US7094246B2 (en) | 2001-12-07 | 2006-08-22 | Abbott Laboratories | Suture trimmer |
| JP4230915B2 (ja) | 2001-12-21 | 2009-02-25 | シムチャ ミロ | 輪状形成リング用移植システム |
| US20030120340A1 (en) | 2001-12-26 | 2003-06-26 | Jan Liska | Mitral and tricuspid valve repair |
| EP2181669A3 (fr) | 2001-12-28 | 2011-11-23 | Edwards Lifesciences AG | Dispositif de traitement de l'insuffisance mitrale |
| US6797001B2 (en) | 2002-03-11 | 2004-09-28 | Cardiac Dimensions, Inc. | Device, assembly and method for mitral valve repair |
| US6699263B2 (en) | 2002-04-05 | 2004-03-02 | Cook Incorporated | Sliding suture anchor |
| US20030199974A1 (en) * | 2002-04-18 | 2003-10-23 | Coalescent Surgical, Inc. | Annuloplasty apparatus and methods |
| US6932813B2 (en) | 2002-05-03 | 2005-08-23 | Scimed Life Systems, Inc. | Ablation systems including insulated energy transmitting elements |
| US7758637B2 (en) | 2003-02-06 | 2010-07-20 | Guided Delivery Systems, Inc. | Delivery devices and methods for heart valve repair |
| US20040243227A1 (en) | 2002-06-13 | 2004-12-02 | Guided Delivery Systems, Inc. | Delivery devices and methods for heart valve repair |
| US20050107811A1 (en) | 2002-06-13 | 2005-05-19 | Guided Delivery Systems, Inc. | Delivery devices and methods for heart valve repair |
| US7883538B2 (en) | 2002-06-13 | 2011-02-08 | Guided Delivery Systems Inc. | Methods and devices for termination |
| US7753922B2 (en) | 2003-09-04 | 2010-07-13 | Guided Delivery Systems, Inc. | Devices and methods for cardiac annulus stabilization and treatment |
| US8287555B2 (en) | 2003-02-06 | 2012-10-16 | Guided Delivery Systems, Inc. | Devices and methods for heart valve repair |
| AU2003245507A1 (en) | 2002-06-13 | 2003-12-31 | Guided Delivery Systems, Inc. | Devices and methods for heart valve repair |
| US20040044364A1 (en) | 2002-08-29 | 2004-03-04 | Devries Robert | Tissue fasteners and related deployment systems and methods |
| AU2003282982B2 (en) | 2002-10-21 | 2009-07-16 | Mitralign Incorporated | Method and apparatus for performing catheter-based annuloplasty using local plications |
| US6656194B1 (en) | 2002-11-05 | 2003-12-02 | Satiety, Inc. | Magnetic anchoring devices |
| US7247134B2 (en) | 2002-11-12 | 2007-07-24 | Myocor, Inc. | Devices and methods for heart valve treatment |
| US6945978B1 (en) | 2002-11-15 | 2005-09-20 | Advanced Cardiovascular Systems, Inc. | Heart valve catheter |
| WO2004045378A2 (fr) | 2002-11-15 | 2004-06-03 | The Government Of The United States Of America As Represented By The Secretary Of Health And Human Services | Procede et dispositif de reparation par catheter de valvules cardiaques |
| US6866673B2 (en) * | 2002-12-20 | 2005-03-15 | Ran Oren | Suture manipulating and/or cutting implement |
| US7947040B2 (en) | 2003-01-21 | 2011-05-24 | Baylis Medical Company Inc | Method of surgical perforation via the delivery of energy |
| EP1608297A2 (fr) | 2003-03-18 | 2005-12-28 | St. Jude Medical, Inc. | Procedes et appareil de remodelage de tissu corporel |
| US20050107871A1 (en) * | 2003-03-30 | 2005-05-19 | Fidel Realyvasquez | Apparatus and methods for valve repair |
| CN1852688A (zh) * | 2003-05-19 | 2006-10-25 | 斯托特药物集团公司 | 组织扩张装置及用于治疗介入的相关方法 |
| US20040254598A1 (en) | 2003-06-16 | 2004-12-16 | Schumacher Brian S. | Suture cutter |
| US20050025120A1 (en) * | 2003-06-18 | 2005-02-03 | O'toole Anthony J.P. | Event scheduling for multi-port xDSL transceivers |
| US7316706B2 (en) | 2003-06-20 | 2008-01-08 | Medtronic Vascular, Inc. | Tensioning device, system, and method for treating mitral valve regurgitation |
| DE10331672A1 (de) * | 2003-07-03 | 2005-01-20 | Bayer Materialscience Ag | Verfahren zur lösemittelfreien Herstellung ethylenisch ungesättigter Polyurethane |
| US7086388B2 (en) * | 2003-08-04 | 2006-08-08 | Delphi Technologies, Inc. | Combination valve for fuel system |
| US20050049634A1 (en) | 2003-08-07 | 2005-03-03 | Scimed Life Systems, Inc. | Medical closure device |
| US7534204B2 (en) * | 2003-09-03 | 2009-05-19 | Guided Delivery Systems, Inc. | Cardiac visualization devices and methods |
| US20050096696A1 (en) * | 2003-11-04 | 2005-05-05 | Forsberg Andrew T. | Arteriotomy closure device with anti-roll anchor |
| US20050143811A1 (en) * | 2003-12-02 | 2005-06-30 | Fidel Realyvasquez | Methods and apparatus for mitral valve repair |
| US20050251189A1 (en) | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Multi-position tissue manipulation assembly |
| EP1699366A4 (fr) | 2003-12-12 | 2011-01-26 | Usgi Medical Inc | Appareil et procede pour former et fixer des plis de tissu gastro-intestinal |
| US20050159810A1 (en) * | 2004-01-15 | 2005-07-21 | Farzan Filsoufi | Devices and methods for repairing cardiac valves |
| US7255675B2 (en) | 2004-03-23 | 2007-08-14 | Michael Gertner | Devices and methods to treat a patient |
| WO2005102179A1 (fr) | 2004-03-31 | 2005-11-03 | Wilson-Cook Medical, Inc. | Dispositif pour couper des sutures |
| US20050251159A1 (en) | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Methods and apparatus for grasping and cinching tissue anchors |
| US8257394B2 (en) | 2004-05-07 | 2012-09-04 | Usgi Medical, Inc. | Apparatus and methods for positioning and securing anchors |
| US7390329B2 (en) | 2004-05-07 | 2008-06-24 | Usgi Medical, Inc. | Methods for grasping and cinching tissue anchors |
| US7736378B2 (en) | 2004-05-07 | 2010-06-15 | Usgi Medical, Inc. | Apparatus and methods for positioning and securing anchors |
| WO2005112784A2 (fr) | 2004-05-14 | 2005-12-01 | Ethicon Endo-Surgery, Inc. | Dispositifs et procedes permettant de bloquer et de couper une suture dans un acte medical |
| US7758626B2 (en) * | 2004-07-20 | 2010-07-20 | Medtronic Vascular, Inc. | Device and method for delivering an endovascular stent-graft having a longitudinally unsupported portion |
| US7749250B2 (en) | 2006-02-03 | 2010-07-06 | Biomet Sports Medicine, Llc | Soft tissue repair assembly and associated method |
| IE20050841A1 (en) | 2004-12-15 | 2006-10-04 | Mednua Ltd | A medical device suitable for use in treatment of a valve |
| US8109945B2 (en) | 2005-02-04 | 2012-02-07 | St. Jude Medical Puerto Rico Llc | Percutaneous suture path tracking device with cutting blade |
| EP1865887A1 (fr) | 2005-03-25 | 2007-12-19 | Ample Medical, Inc. | Dispositif, systemes et procedes pour retablir la forme d'un anneau de valvule cardiaque |
| US20070083236A1 (en) | 2005-06-24 | 2007-04-12 | Smith & Nephew, Inc. | Methods and devices for tissue repair |
| US8252005B2 (en) | 2005-06-30 | 2012-08-28 | Edwards Lifesciences Corporation | System, apparatus, and method for fastening tissue |
| US20090018655A1 (en) | 2007-07-13 | 2009-01-15 | John Brunelle | Composite Implant for Surgical Repair |
| US7731732B2 (en) | 2007-08-31 | 2010-06-08 | Ken Christopher G M | Closure medical device |
-
2007
- 2007-03-13 US US11/685,241 patent/US20080228266A1/en not_active Abandoned
- 2007-03-13 US US11/685,239 patent/US8845723B2/en active Active
- 2007-03-13 US US11/685,240 patent/US20080228265A1/en not_active Abandoned
-
2008
- 2008-03-12 WO PCT/US2008/056620 patent/WO2008112740A2/fr not_active Ceased
-
2013
- 2013-08-27 US US14/010,950 patent/US9358111B2/en not_active Expired - Fee Related
-
2014
- 2014-08-18 US US14/462,177 patent/US9750608B2/en not_active Expired - Fee Related
-
2016
- 2016-05-02 US US15/144,182 patent/US20160317304A1/en not_active Abandoned
Patent Citations (92)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2143910A (en) * | 1934-03-30 | 1939-01-17 | Davis & Geck Inc | Ribbon gut and method of using the same |
| US3674014A (en) * | 1969-10-28 | 1972-07-04 | Astra Meditec Ab | Magnetically guidable catheter-tip and method |
| US3841521A (en) * | 1970-08-17 | 1974-10-15 | R Jarvik | Repeating ligature guns, multi-ligature cartridges and preformed ligatures therefor |
| US3794041A (en) * | 1971-11-30 | 1974-02-26 | Yeda Res & Dev | Gastrointestinal catheter |
| US4055861A (en) * | 1975-04-11 | 1977-11-01 | Rhone-Poulenc Industries | Support for a natural human heart valve |
| US3986493A (en) * | 1975-07-28 | 1976-10-19 | Hendren Iii William Hardy | Electromagnetic bougienage method |
| US4042979A (en) * | 1976-07-12 | 1977-08-23 | Angell William W | Valvuloplasty ring and prosthetic method |
| US4369787A (en) * | 1978-09-26 | 1983-01-25 | Laschal Instruments Corp. | Method of cutting a suture |
| US4489446A (en) * | 1982-07-14 | 1984-12-25 | Reed Charles C | Heart valve prosthesis |
| US4532926A (en) * | 1983-06-20 | 1985-08-06 | Ethicon, Inc. | Two-piece tissue fastener with ratchet leg staple and sealable latching receiver |
| US5016353A (en) * | 1986-02-19 | 1991-05-21 | American Safety Razor Company | Suture cutter |
| US5123914A (en) * | 1986-05-19 | 1992-06-23 | Cook Incorporated | Visceral anchor for visceral wall mobilization |
| US5061277A (en) * | 1986-08-06 | 1991-10-29 | Baxter International Inc. | Flexible cardiac valvular support prosthesis |
| US5061277B1 (en) * | 1986-08-06 | 2000-02-29 | Baxter Travenol Lab | Flexible cardiac valvular support prosthesis |
| US4809713A (en) * | 1987-10-28 | 1989-03-07 | Joseph Grayzel | Catheter with magnetic fixation |
| US4945912A (en) * | 1988-11-25 | 1990-08-07 | Sensor Electronics, Inc. | Catheter with radiofrequency heating applicator |
| US4917698A (en) * | 1988-12-22 | 1990-04-17 | Baxter International Inc. | Multi-segmented annuloplasty ring prosthesis |
| US5104407B1 (en) * | 1989-02-13 | 1999-09-21 | Baxter Int | Selectively flexible annuloplasty ring |
| US5104407A (en) * | 1989-02-13 | 1992-04-14 | Baxter International Inc. | Selectively flexible annuloplasty ring |
| US5171232A (en) * | 1989-06-13 | 1992-12-15 | Cordis Corporation | Catheter having highly radiopaque, flexible tip |
| US5171232B1 (en) * | 1989-06-13 | 1997-10-28 | Cordis Corp | Catheter having highly radiopaque flexible tip |
| US5041130A (en) * | 1989-07-31 | 1991-08-20 | Baxter International Inc. | Flexible annuloplasty ring and holder |
| US5192302A (en) * | 1989-12-04 | 1993-03-09 | Kensey Nash Corporation | Plug devices for sealing punctures and methods of use |
| US5797939A (en) * | 1989-12-05 | 1998-08-25 | Yoon; Inbae | Endoscopic scissors with longitudinal operating channel |
| US5364393A (en) * | 1990-07-02 | 1994-11-15 | Heart Technology, Inc. | Tissue dissipative recanalization catheter |
| US5041129A (en) * | 1990-07-02 | 1991-08-20 | Acufex Microsurgical, Inc. | Slotted suture anchor and method of anchoring a suture |
| US5360444A (en) * | 1991-03-19 | 1994-11-01 | Kenji Kusuhara | Occluder supporter and a method of attachment thereof |
| US5201880A (en) * | 1992-01-27 | 1993-04-13 | Pioneering Technologies, Inc. | Mitral and tricuspid annuloplasty rings |
| US5674279A (en) * | 1992-01-27 | 1997-10-07 | Medtronic, Inc. | Annuloplasty and suture rings |
| US5203777A (en) * | 1992-03-19 | 1993-04-20 | Lee Peter Y | Radiopaque marker system for a tubular device |
| US5776080A (en) * | 1992-08-12 | 1998-07-07 | Scimed Life Systems, Inc. | Shaft movement control apparatus |
| US5623943A (en) * | 1992-08-12 | 1997-04-29 | Scimed Life Systems, Inc. | Magnetic medical shaft movement control device and method |
| US5306296A (en) * | 1992-08-21 | 1994-04-26 | Medtronic, Inc. | Annuloplasty and suture rings |
| US5337736A (en) * | 1992-09-30 | 1994-08-16 | Reddy Pratap K | Method of using a laparoscopic retractor |
| US5571215A (en) * | 1993-02-22 | 1996-11-05 | Heartport, Inc. | Devices and methods for intracardiac procedures |
| US5682906A (en) * | 1993-02-22 | 1997-11-04 | Heartport, Inc. | Methods of performing intracardiac procedures on an arrested heart |
| US5306234A (en) * | 1993-03-23 | 1994-04-26 | Johnson W Dudley | Method for closing an atrial appendage |
| USRE36974E (en) * | 1993-05-14 | 2000-11-28 | Bonutti; Peter M. | Suture anchor |
| US5607471A (en) * | 1993-08-03 | 1997-03-04 | Jacques Seguin | Prosthetic ring for heart surgery |
| US5450860A (en) * | 1993-08-31 | 1995-09-19 | W. L. Gore & Associates, Inc. | Device for tissue repair and method for employing same |
| US5464023A (en) * | 1994-01-31 | 1995-11-07 | Cordis Corporation | Magnetic exchange device for catheters |
| US5626590A (en) * | 1994-02-10 | 1997-05-06 | Wilk; Peter J. | Laparoscopic suturing technique and associated device |
| US5429131A (en) * | 1994-02-25 | 1995-07-04 | The Regents Of The University Of California | Magnetized electrode tip catheter |
| US5545178A (en) * | 1994-04-29 | 1996-08-13 | Kensey Nash Corporation | System for closing a percutaneous puncture formed by a trocar to prevent tissue at the puncture from herniating |
| US5452513A (en) * | 1994-06-29 | 1995-09-26 | Eric Hulsman | Suture cutter |
| US5565122A (en) * | 1994-06-29 | 1996-10-15 | Eric Hulsman | Suture cutting and cauterizing method using radiant heat |
| US5593424A (en) * | 1994-08-10 | 1997-01-14 | Segmed, Inc. | Apparatus and method for reducing and stabilizing the circumference of a vascular structure |
| US5706827A (en) * | 1994-09-21 | 1998-01-13 | Scimed Life Systems, Inc. | Magnetic lumen catheter |
| US5640955A (en) * | 1995-02-14 | 1997-06-24 | Daig Corporation | Guiding introducers for use in the treatment of accessory pathways around the mitral valve using a retrograde approach |
| US5690656A (en) * | 1995-06-27 | 1997-11-25 | Cook Incorporated | Method and apparatus for creating abdominal visceral anastomoses |
| US5967984A (en) * | 1995-06-30 | 1999-10-19 | Boston Scientific Corporation | Ultrasound imaging catheter with a cutting element |
| US5716399A (en) * | 1995-10-06 | 1998-02-10 | Cardiomend Llc | Methods of heart valve repair |
| US5716367A (en) * | 1995-10-18 | 1998-02-10 | Nissho Corporation | Catheter assembly for intracardiac suture |
| US6050472A (en) * | 1996-04-26 | 2000-04-18 | Olympus Optical Co., Ltd. | Surgical anastomosis stapler |
| US5669919A (en) * | 1996-08-16 | 1997-09-23 | Medtronic, Inc. | Annuloplasty system |
| US5716397A (en) * | 1996-12-06 | 1998-02-10 | Medtronic, Inc. | Annuloplasty device with removable stiffening element |
| US5879366A (en) * | 1996-12-20 | 1999-03-09 | W.L. Gore & Associates, Inc. | Self-expanding defect closure device and method of making and using |
| US5776189A (en) * | 1997-03-05 | 1998-07-07 | Khalid; Naqeeb | Cardiac valvular support prosthesis |
| US6561019B1 (en) * | 1997-04-04 | 2003-05-13 | Siemens Aktiengesellschaft | Method and apparatus for tensile testing a spliced connection of fibers in a fiber splicing device |
| US5851185A (en) * | 1997-07-02 | 1998-12-22 | Cabot Technology Corporation | Apparatus for alignment of tubular organs |
| US6113611A (en) * | 1998-05-28 | 2000-09-05 | Advanced Vascular Technologies, Llc | Surgical fastener and delivery system |
| US20050283192A1 (en) * | 1999-12-02 | 2005-12-22 | Torrie Paul A | Closure device and method for tissue repair |
| US20020087178A1 (en) * | 2000-08-25 | 2002-07-04 | Nobles Anthony A. | Suture cutter |
| US20030220685A1 (en) * | 2001-04-24 | 2003-11-27 | Hlavka Edwin J. | Method and apparatus for catheter-based annuloplasty using local plications |
| US7037334B1 (en) * | 2001-04-24 | 2006-05-02 | Mitralign, Inc. | Method and apparatus for catheter-based annuloplasty using local plications |
| US20050125011A1 (en) * | 2001-04-24 | 2005-06-09 | Spence Paul A. | Tissue fastening systems and methods utilizing magnetic guidance |
| US20060069429A1 (en) * | 2001-04-24 | 2006-03-30 | Spence Paul A | Tissue fastening systems and methods utilizing magnetic guidance |
| US20030078465A1 (en) * | 2001-10-16 | 2003-04-24 | Suresh Pai | Systems for heart treatment |
| US6949122B2 (en) * | 2001-11-01 | 2005-09-27 | Cardiac Dimensions, Inc. | Focused compression mitral valve device and method |
| US20030144697A1 (en) * | 2002-01-30 | 2003-07-31 | Cardiac Dimensions, Inc. | Fixed length anchor and pull mitral valve device and method |
| US7004958B2 (en) * | 2002-03-06 | 2006-02-28 | Cardiac Dimensions, Inc. | Transvenous staples, assembly and method for mitral valve repair |
| US20040049211A1 (en) * | 2002-06-12 | 2004-03-11 | Mitral Interventions, Inc. | Method and apparatus for tissue connection |
| US20050119735A1 (en) * | 2002-10-21 | 2005-06-02 | Spence Paul A. | Tissue fastening systems and methods utilizing magnetic guidance |
| US20050119734A1 (en) * | 2002-10-21 | 2005-06-02 | Spence Paul A. | Tissue fastening systems and methods utilizing magnetic guidance |
| US20040122456A1 (en) * | 2002-12-11 | 2004-06-24 | Saadat Vahid C. | Methods and apparatus for gastric reduction |
| US20050177228A1 (en) * | 2003-12-16 | 2005-08-11 | Solem Jan O. | Device for changing the shape of the mitral annulus |
| US20050267571A1 (en) * | 2003-12-23 | 2005-12-01 | Spence Paul A | Tissue fastening systems and methods utilizing magnetic guidance |
| US20080275503A1 (en) * | 2003-12-23 | 2008-11-06 | Mitralign, Inc. | Method of heart valve repair |
| US20080228267A1 (en) * | 2003-12-23 | 2008-09-18 | Mitralign, Inc. | Devices and methods for introducing elements into tissue |
| US7166127B2 (en) * | 2003-12-23 | 2007-01-23 | Mitralign, Inc. | Tissue fastening systems and methods utilizing magnetic guidance |
| US20070112424A1 (en) * | 2003-12-23 | 2007-05-17 | Mitralign, Inc. | Catheter based tissue fastening systems and methods |
| US20070080188A1 (en) * | 2003-12-23 | 2007-04-12 | Mitralign, Inc. | Tissue fastening systems and methods |
| US20050267533A1 (en) * | 2004-03-23 | 2005-12-01 | Michael Gertner | Methods and devices for the surgical creation of satiety and biofeedback pathways |
| US20050251208A1 (en) * | 2004-05-07 | 2005-11-10 | Usgi Medical Inc. | Linear anchors for anchoring to tissue |
| US20050288694A1 (en) * | 2004-06-23 | 2005-12-29 | Stepehen Solomon | Adjustable percutaneous stomach lumen restriction device |
| US20060009784A1 (en) * | 2004-07-07 | 2006-01-12 | Percutaneous Systems, Inc. | Methods and apparatus for deploying conformed structures in body lumens |
| US20060212045A1 (en) * | 2005-03-08 | 2006-09-21 | Peter Schilling | Surgical suture cutter |
| US20070010857A1 (en) * | 2005-07-05 | 2007-01-11 | Mitralign, Inc. | Tissue anchor, anchoring system and methods of using the same |
| US20070106310A1 (en) * | 2005-11-10 | 2007-05-10 | Goldin Mark A | Suture cutter |
| US20080228198A1 (en) * | 2007-03-13 | 2008-09-18 | Mitralign, Inc. | Suture cutter and method of cutting suture |
| US20080228266A1 (en) * | 2007-03-13 | 2008-09-18 | Mitralign, Inc. | Plication assistance devices and methods |
| US20080228165A1 (en) * | 2007-03-13 | 2008-09-18 | Mitralign, Inc. | Systems and methods for introducing elements into tissue |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8974473B2 (en) | 1999-05-20 | 2015-03-10 | Sentreheart, Inc. | Methods and apparatus for transpericardial left atrial appendage closure |
| US8721663B2 (en) | 1999-05-20 | 2014-05-13 | Sentreheart, Inc. | Methods and apparatus for transpericardial left atrial appendage closure |
| US9724105B2 (en) | 1999-05-20 | 2017-08-08 | Sentreheart, Inc. | Methods and apparatus for transpericardial left atrial appendage closure |
| US9358112B2 (en) | 2001-04-24 | 2016-06-07 | Mitralign, Inc. | Method and apparatus for catheter-based annuloplasty using local plications |
| US8460371B2 (en) | 2002-10-21 | 2013-06-11 | Mitralign, Inc. | Method and apparatus for performing catheter-based annuloplasty using local plications |
| US20040172046A1 (en) * | 2002-10-21 | 2004-09-02 | Hlavka Edwin J. | Method and apparatus for performing catheter-based annuloplasty using local plications |
| US20050119735A1 (en) * | 2002-10-21 | 2005-06-02 | Spence Paul A. | Tissue fastening systems and methods utilizing magnetic guidance |
| US20050119734A1 (en) * | 2002-10-21 | 2005-06-02 | Spence Paul A. | Tissue fastening systems and methods utilizing magnetic guidance |
| US10028833B2 (en) | 2002-10-21 | 2018-07-24 | Mitralign, Inc. | Tissue fastening systems and methods utilizing magnetic guidance |
| US8979923B2 (en) | 2002-10-21 | 2015-03-17 | Mitralign, Inc. | Tissue fastening systems and methods utilizing magnetic guidance |
| US9271819B2 (en) | 2003-10-09 | 2016-03-01 | Sentreheart, Inc. | Apparatus and method for the ligation of tissue |
| US11350944B2 (en) | 2003-10-09 | 2022-06-07 | Sentreheart Llc | Apparatus and method for the ligation of tissue |
| US10806460B2 (en) | 2003-10-09 | 2020-10-20 | Sentreheart Llc | Apparatus and method for the ligation of tissue |
| US8795297B2 (en) | 2003-10-09 | 2014-08-05 | Sentreheart, Inc. | Apparatus and method for the ligation of tissue |
| US10327780B2 (en) | 2003-10-09 | 2019-06-25 | Sentreheart, Inc. | Apparatus and method for the ligation of tissue |
| US8142493B2 (en) | 2003-12-23 | 2012-03-27 | Mitralign, Inc. | Method of heart valve repair |
| US20080228267A1 (en) * | 2003-12-23 | 2008-09-18 | Mitralign, Inc. | Devices and methods for introducing elements into tissue |
| US8864822B2 (en) | 2003-12-23 | 2014-10-21 | Mitralign, Inc. | Devices and methods for introducing elements into tissue |
| US9526613B2 (en) | 2005-03-17 | 2016-12-27 | Valtech Cardio Ltd. | Mitral valve treatment techniques |
| US9522006B2 (en) | 2005-04-07 | 2016-12-20 | Sentreheart, Inc. | Apparatus and method for the ligation of tissue |
| US9814454B2 (en) | 2005-07-05 | 2017-11-14 | Mitralign, Inc. | Tissue anchor and anchoring system |
| US10695046B2 (en) | 2005-07-05 | 2020-06-30 | Edwards Lifesciences Corporation | Tissue anchor and anchoring system |
| US20090076547A1 (en) * | 2005-07-05 | 2009-03-19 | Mitralign, Inc. | Tissue anchor and anchoring system |
| US9259218B2 (en) | 2005-07-05 | 2016-02-16 | Mitralign, Inc. | Tissue anchor and anchoring system |
| US8951286B2 (en) | 2005-07-05 | 2015-02-10 | Mitralign, Inc. | Tissue anchor and anchoring system |
| US8951285B2 (en) | 2005-07-05 | 2015-02-10 | Mitralign, Inc. | Tissue anchor, anchoring system and methods of using the same |
| US20080228165A1 (en) * | 2007-03-13 | 2008-09-18 | Mitralign, Inc. | Systems and methods for introducing elements into tissue |
| US9358111B2 (en) | 2007-03-13 | 2016-06-07 | Mitralign, Inc. | Tissue anchors, systems and methods, and devices |
| US8911461B2 (en) | 2007-03-13 | 2014-12-16 | Mitralign, Inc. | Suture cutter and method of cutting suture |
| US11660190B2 (en) | 2007-03-13 | 2023-05-30 | Edwards Lifesciences Corporation | Tissue anchors, systems and methods, and devices |
| US8845723B2 (en) | 2007-03-13 | 2014-09-30 | Mitralign, Inc. | Systems and methods for introducing elements into tissue |
| US20080228198A1 (en) * | 2007-03-13 | 2008-09-18 | Mitralign, Inc. | Suture cutter and method of cutting suture |
| US11826050B2 (en) | 2007-03-30 | 2023-11-28 | Atricure, Inc. | Devices, systems, and methods for closing the left atrial appendage |
| US11020122B2 (en) | 2007-03-30 | 2021-06-01 | Sentreheart Llc | Methods for closing the left atrial appendage |
| US10966725B2 (en) | 2007-03-30 | 2021-04-06 | Sentreheart Llc | Devices and systems for closing the left atrial appendage |
| US8986325B2 (en) | 2007-03-30 | 2015-03-24 | Sentreheart, Inc. | Devices, systems, and methods for closing the left atrial appendage |
| US8771297B2 (en) | 2007-03-30 | 2014-07-08 | Sentreheart, Inc. | Devices, systems, and methods for closing the left atrial appendage |
| US9498223B2 (en) | 2007-03-30 | 2016-11-22 | Sentreheart, Inc. | Devices for closing the left atrial appendage |
| US8469983B2 (en) * | 2007-09-20 | 2013-06-25 | Sentreheart, Inc. | Devices and methods for remote suture management |
| US8632585B2 (en) | 2008-04-18 | 2014-01-21 | Medtronic Corevalve, Inc. | Apparatus for treating a heart valve, in particular a mitral valve |
| US8262724B2 (en) | 2008-04-18 | 2012-09-11 | Medtronic Corevalve, Inc. | Apparatus for treating a heart valve, in particular a mitral valve |
| US20100030328A1 (en) * | 2008-04-18 | 2010-02-04 | Medtronic, Inc. | Apparatus for Treating a Heart Valve, in Particular a Mitral Valve |
| US20100070028A1 (en) * | 2008-09-12 | 2010-03-18 | Mitralign, Inc. | Tissue plication device and method for its use |
| US8945211B2 (en) * | 2008-09-12 | 2015-02-03 | Mitralign, Inc. | Tissue plication device and method for its use |
| US8795298B2 (en) | 2008-10-10 | 2014-08-05 | Guided Delivery Systems Inc. | Tether tensioning devices and related methods |
| US9636106B2 (en) | 2008-10-10 | 2017-05-02 | Ancora Heart, Inc. | Termination devices and related methods |
| US10856986B2 (en) | 2008-12-22 | 2020-12-08 | Valtech Cardio, Ltd. | Adjustable annuloplasty devices and adjustment mechanisms therefor |
| US9713530B2 (en) | 2008-12-22 | 2017-07-25 | Valtech Cardio, Ltd. | Adjustable annuloplasty devices and adjustment mechanisms therefor |
| US9662209B2 (en) | 2008-12-22 | 2017-05-30 | Valtech Cardio, Ltd. | Contractible annuloplasty structures |
| US10470882B2 (en) | 2008-12-22 | 2019-11-12 | Valtech Cardio, Ltd. | Closure element for use with annuloplasty structure |
| US9636224B2 (en) | 2008-12-22 | 2017-05-02 | Valtech Cardio, Ltd. | Deployment techniques for annuloplasty ring and over-wire rotation tool |
| US20110011917A1 (en) * | 2008-12-31 | 2011-01-20 | Hansen Medical, Inc. | Methods, devices, and kits for treating valve prolapse |
| US9561104B2 (en) | 2009-02-17 | 2017-02-07 | Valtech Cardio, Ltd. | Actively-engageable movement-restriction mechanism for use with an annuloplasty structure |
| US11950784B2 (en) | 2009-04-01 | 2024-04-09 | Atricure, Inc. | Tissue ligation devices and controls therefor |
| US10799241B2 (en) | 2009-04-01 | 2020-10-13 | Sentreheart Llc | Tissue ligation devices and controls therefor |
| US9198664B2 (en) | 2009-04-01 | 2015-12-01 | Sentreheart, Inc. | Tissue ligation devices and controls therefor |
| US9474606B2 (en) | 2009-05-04 | 2016-10-25 | Valtech Cardio, Ltd. | Over-wire implant contraction methods |
| US9968452B2 (en) | 2009-05-04 | 2018-05-15 | Valtech Cardio, Ltd. | Annuloplasty ring delivery cathethers |
| US9592122B2 (en) | 2009-05-07 | 2017-03-14 | Valtech Cardio, Ltd | Annuloplasty ring with intra-ring anchoring |
| US9937042B2 (en) | 2009-05-07 | 2018-04-10 | Valtech Cardio, Ltd. | Multiple anchor delivery tool |
| US10856987B2 (en) | 2009-05-07 | 2020-12-08 | Valtech Cardio, Ltd. | Multiple anchor delivery tool |
| US10004495B2 (en) | 2009-07-24 | 2018-06-26 | Depuy Mitek, Llc | Methods and devices for repairing and anchoring damaged tissue |
| US12016545B2 (en) | 2009-07-24 | 2024-06-25 | DePuy Synthes Products, Inc. | Methods and devices for repairing meniscal tissue |
| US8828053B2 (en) | 2009-07-24 | 2014-09-09 | Depuy Mitek, Llc | Methods and devices for repairing and anchoring damaged tissue |
| US11141149B2 (en) | 2009-07-24 | 2021-10-12 | DePuy Synthes Products, Inc. | Methods and devices for repairing and anchoring damaged tissue |
| US8814903B2 (en) | 2009-07-24 | 2014-08-26 | Depuy Mitek, Llc | Methods and devices for repairing meniscal tissue |
| US10433830B2 (en) | 2009-07-24 | 2019-10-08 | DePuy Synthes Products, Inc. | Methods and devices for repairing meniscal tissue |
| US9622861B2 (en) | 2009-12-02 | 2017-04-18 | Valtech Cardio, Ltd. | Tool for actuating an adjusting mechanism |
| US10433956B2 (en) | 2010-02-24 | 2019-10-08 | Medtronic Ventor Technologies Ltd. | Mitral prosthesis and methods for implantation |
| US9072603B2 (en) | 2010-02-24 | 2015-07-07 | Medtronic Ventor Technologies, Ltd. | Mitral prosthesis and methods for implantation |
| US20110208298A1 (en) * | 2010-02-24 | 2011-08-25 | Medtronic Ventor Technologies Ltd | Mitral Prosthesis and Methods for Implantation |
| US20110208297A1 (en) * | 2010-02-24 | 2011-08-25 | Medtronic Ventor Technologies Ltd. | Mitral Prosthesis and Methods for Implantation |
| US11918461B2 (en) | 2010-03-05 | 2024-03-05 | Edwards Lifesciences Corporation | Methods for treating a deficient native mitral valve |
| US11890187B2 (en) | 2010-03-05 | 2024-02-06 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves |
| US12245933B2 (en) | 2010-03-05 | 2025-03-11 | Edwards Lifesciences Corporation | Methods for treating a deficient native mitral valve |
| US10405919B2 (en) | 2010-04-13 | 2019-09-10 | Sentreheart, Inc. | Methods and devices for treating atrial fibrillation |
| US9486281B2 (en) | 2010-04-13 | 2016-11-08 | Sentreheart, Inc. | Methods and devices for accessing and delivering devices to a heart |
| US8357195B2 (en) | 2010-04-15 | 2013-01-22 | Medtronic, Inc. | Catheter based annuloplasty system and method |
| US11116492B2 (en) | 2010-04-27 | 2021-09-14 | DePuy Synthes Products, Inc. | Insertion instrument for anchor assembly |
| US9713464B2 (en) | 2010-04-27 | 2017-07-25 | DePuy Synthes Products, Inc. | Anchor assembly including expandable anchor |
| US9451938B2 (en) | 2010-04-27 | 2016-09-27 | DePuy Synthes Products, Inc. | Insertion instrument for anchor assembly |
| US9795482B2 (en) | 2010-04-27 | 2017-10-24 | Medtronic, Inc. | Prosthetic heart valve devices and methods of valve repair |
| US9743919B2 (en) | 2010-04-27 | 2017-08-29 | DePuy Synthes Products, Inc. | Stitch lock for attaching two or more structures |
| US10595839B2 (en) | 2010-04-27 | 2020-03-24 | DePuy Synthes Products, Inc. | Insertion instrument for anchor assembly |
| US9597064B2 (en) | 2010-04-27 | 2017-03-21 | DePuy Synthes Products, Inc. | Methods for approximating a tissue defect using an anchor assembly |
| US11779318B2 (en) | 2010-04-27 | 2023-10-10 | DePuy Synthes Products, Inc. | Insertion instrument for anchor assembly |
| US9724080B2 (en) | 2010-04-27 | 2017-08-08 | DePuy Synthes Products, Inc. | Insertion instrument for anchor assembly |
| US10820894B2 (en) | 2010-04-27 | 2020-11-03 | DePuy Synthes Products, Inc. | Methods for approximating a tissue defect using an anchor assembly |
| US9439643B2 (en) | 2010-06-09 | 2016-09-13 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures, transfascial suture assemblies, and methods of transfascial suturing |
| US10335139B2 (en) | 2010-06-09 | 2019-07-02 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures, transfascial suture assemblies, and methods of transfascial suturing |
| US8790356B2 (en) | 2010-06-09 | 2014-07-29 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures, transfascial suture assemblies, and methods of transfascial suturing |
| US10492777B2 (en) | 2010-06-09 | 2019-12-03 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures, transfascial suture assemblies, and methods of transfascial suturing |
| US9393007B2 (en) | 2010-06-09 | 2016-07-19 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures, transfascial assemblies, and methods of transfascial suturing |
| US9629716B2 (en) | 2010-07-19 | 2017-04-25 | Bmeye B.V. | Cardiac valve repair system and methods of use |
| US10743988B2 (en) | 2010-07-19 | 2020-08-18 | Bmeye B.V. | Cardiac valve repair system and methods of use |
| US8657872B2 (en) | 2010-07-19 | 2014-02-25 | Jacques Seguin | Cardiac valve repair system and methods of use |
| US10383724B2 (en) | 2010-07-19 | 2019-08-20 | Bmeye B.V. | Cardiac valve repair system and methods of use |
| US11504234B2 (en) | 2010-07-19 | 2022-11-22 | Bmeye B.V. | Cardiac valve repair system and methods of use |
| US10813752B2 (en) | 2010-07-19 | 2020-10-27 | Bmeye B.V. | Cardiac valve repair system and methods of use |
| US12239532B2 (en) | 2010-07-19 | 2025-03-04 | Bmeye B.V. | Cardiac valve repair system and methods of use |
| EP2446831A2 (fr) | 2010-10-27 | 2012-05-02 | Mitralign, Inc. | Dispositif manuel pour le déploiement contrôlé d'un ancrage de tissus |
| EP3799800A1 (fr) | 2010-10-27 | 2021-04-07 | Edwards Lifesciences Corporation | Dispositif manuel pour le déploiement contrôlé d'un ancrage de tissus |
| US9750493B2 (en) | 2010-10-27 | 2017-09-05 | Mitralign, Inc. | Hand operated device for controlled deployment of a tissue anchor and method of using the same |
| US9307977B2 (en) | 2010-11-04 | 2016-04-12 | Conmed Corporation | Method and apparatus for securing an object to bone, including the provision and use of a novel suture assembly for securing suture to bone |
| US9119893B2 (en) | 2010-11-04 | 2015-09-01 | Linvatec Corporation | Method and apparatus for securing an object to bone, including the provision and use of a novel suture assembly for securing an object to bone |
| US9307978B2 (en) | 2010-11-04 | 2016-04-12 | Linvatec Corporation | Method and apparatus for securing an object to bone, including the provision and use of a novel suture assembly for securing an object to bone |
| US10292695B2 (en) | 2010-11-23 | 2019-05-21 | Medos International Sàrl | Surgical filament snare assemblies |
| US12329371B2 (en) | 2010-11-23 | 2025-06-17 | Medos International Sarl | Surgical filament snare assemblies |
| US9179908B2 (en) | 2010-11-23 | 2015-11-10 | Medos International Sàrl | Surgical filament snare assemblies |
| US9895145B2 (en) | 2010-11-23 | 2018-02-20 | Medos International Sàrl | Surgical filament snare assemblies |
| US9532778B2 (en) | 2010-11-23 | 2017-01-03 | Medos International Sàrl | Surgical filament snare assemblies |
| US9345468B2 (en) | 2010-11-23 | 2016-05-24 | Medos International Sárl | Surgical filament snare assemblies |
| US8821544B2 (en) | 2010-11-23 | 2014-09-02 | Depuy Mitek, Llc | Surgical filament snare assemblies |
| US8821545B2 (en) | 2010-11-23 | 2014-09-02 | Depuy Mitek, Llc | Surgical filament snare assemblies |
| US10912549B2 (en) | 2010-11-23 | 2021-02-09 | Medos International Sàrl | Surgical filament snare assemblies |
| US9198653B2 (en) | 2010-11-23 | 2015-12-01 | Medos International Sàrl | Surgical filament snare assemblies |
| US12357294B2 (en) | 2010-11-23 | 2025-07-15 | Medos International Sàrl | Surgical filament snare assemblies |
| US8814905B2 (en) | 2010-11-23 | 2014-08-26 | Depuy Mitek, Llc | Surgical filament snare assemblies |
| US11039827B2 (en) | 2010-11-23 | 2021-06-22 | Medos International Sàrl | Surgical filament snare assemblies |
| EP2465568A1 (fr) | 2010-12-19 | 2012-06-20 | Mitralign, Inc. | Cathéter guide orientable doté d'une forme incurvée préformée |
| US9833229B2 (en) | 2010-12-23 | 2017-12-05 | Medos International Sàrl | Adjustable anchor systems and methods |
| US9095331B2 (en) | 2010-12-23 | 2015-08-04 | Medos International Sàrl | Adjustable anchor systems and methods |
| US8821543B2 (en) | 2010-12-23 | 2014-09-02 | Depuy Mitek, Llc | Adjustable anchor systems and methods |
| US10835231B2 (en) | 2010-12-23 | 2020-11-17 | Medos International Sàrl | Adjustable anchor systems and methods |
| US8974495B2 (en) | 2010-12-23 | 2015-03-10 | Medos International Sàrl | Adjustable anchor systems and methods |
| US9445898B2 (en) | 2011-03-01 | 2016-09-20 | Medtronic Ventor Technologies Ltd. | Mitral valve repair |
| US8454656B2 (en) | 2011-03-01 | 2013-06-04 | Medtronic Ventor Technologies Ltd. | Self-suturing anchors |
| US9737397B2 (en) | 2011-03-01 | 2017-08-22 | Medtronic Ventor Technologies, Ltd. | Mitral valve repair |
| US11751993B2 (en) | 2011-03-01 | 2023-09-12 | Medtronic Ventor Technologies Ltd. | Methods of delivering and deploying a heart valve apparatus at a mitral valve |
| US9345470B2 (en) | 2011-03-01 | 2016-05-24 | Medtronic Ventor Technologies Ltd. | Self-suturing anchors |
| US10098731B2 (en) | 2011-03-01 | 2018-10-16 | Medtronic Ventor Technologies Ltd. | Mitral valve repair |
| US10543086B2 (en) | 2011-03-01 | 2020-01-28 | Medtronic Ventor Technologies Ltd. | Methods of delivering and deploying a heart valve apparatus at a mitral valve |
| US11026690B2 (en) | 2011-06-08 | 2021-06-08 | Sentreheart Llc | Tissue ligation devices and tensioning devices therefor |
| US9498206B2 (en) | 2011-06-08 | 2016-11-22 | Sentreheart, Inc. | Tissue ligation devices and tensioning devices therefor |
| US10792152B2 (en) | 2011-06-23 | 2020-10-06 | Valtech Cardio, Ltd. | Closed band for percutaneous annuloplasty |
| US9826972B2 (en) | 2011-10-24 | 2017-11-28 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures, transfascial suture assemblies and methods of transfascial suturing |
| US11317905B2 (en) | 2011-11-07 | 2022-05-03 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures and methods of transfascial suturing |
| US9924938B2 (en) | 2011-11-07 | 2018-03-27 | C.R. Bard, Inc. | Instruments for delivering transfascial sutures and methods of transfascial suturing |
| US9724192B2 (en) | 2011-11-08 | 2017-08-08 | Valtech Cardio, Ltd. | Controlled steering functionality for implant-delivery tool |
| US10568738B2 (en) | 2011-11-08 | 2020-02-25 | Valtech Cardio, Ltd. | Controlled steering functionality for implant-delivery tool |
| US12295840B2 (en) | 2012-01-31 | 2025-05-13 | Mitral Valve Technologies Sarl | Valve docking devices, systems and methods |
| US11925553B2 (en) | 2012-01-31 | 2024-03-12 | Mitral Valve Technologies Sarl | Valve docking devices, systems and methods |
| US11376124B2 (en) | 2012-01-31 | 2022-07-05 | Mitral Valve Technologies Sarl | Valve docking devices, systems and methods |
| US10226339B2 (en) | 2012-01-31 | 2019-03-12 | Mitral Valve Technologies Sarl | Mitral valve docking devices, systems and methods |
| US11166812B2 (en) | 2012-01-31 | 2021-11-09 | Mitral Valve Technologies Sari | Valve docking devices, systems and methods |
| US9872678B2 (en) | 2012-03-30 | 2018-01-23 | Medos International Sarl | Surgical filament assemblies |
| US8790370B2 (en) | 2012-03-30 | 2014-07-29 | Depuy Mitek, Llc | Surgical filament assemblies |
| US11771414B2 (en) | 2012-03-30 | 2023-10-03 | Medos International Sarl | Surgical filament assemblies |
| US10751041B2 (en) | 2012-03-30 | 2020-08-25 | Medos International Sarl | Surgical filament assemblies |
| US9345567B2 (en) | 2012-05-07 | 2016-05-24 | Medos International Sàrl | Systems, devices, and methods for securing tissue using snare assemblies and soft anchors |
| US12336700B2 (en) | 2012-05-07 | 2025-06-24 | Medos International Sarl | Systems, devices, and methods for securing tissue |
| US9060763B2 (en) | 2012-05-07 | 2015-06-23 | Medos International Sàrl | Systems, devices, and methods for securing tissue |
| US10524777B2 (en) | 2012-05-07 | 2020-01-07 | Medos International Sàrl | Systems, devices, and methods for securing tissue |
| US9795373B2 (en) | 2012-05-07 | 2017-10-24 | Medos International Sàrl | Systems, devices, and methods for securing tissue using a suture having one or more protrusions |
| US11564676B2 (en) | 2012-05-07 | 2023-01-31 | Medos International Sarl | Systems, devices, and methods for securing tissue |
| US9757116B2 (en) | 2012-05-07 | 2017-09-12 | Medos International Sárl | Systems, devices, and methods for securing tissue |
| US9034013B2 (en) | 2012-05-07 | 2015-05-19 | Medos International Sàrl | Systems, devices, and methods for securing tissue using a suture having one or more protrusions |
| US9060764B2 (en) | 2012-05-07 | 2015-06-23 | Medos International Sàrl | Systems, devices, and methods for securing tissue |
| US10271833B2 (en) | 2012-05-07 | 2019-04-30 | Medos International Sàrl | Systems, devices, and methods for securing tissue using snare assemblies and soft anchors |
| US8894684B2 (en) | 2012-05-07 | 2014-11-25 | Medos International Sàrl | Systems, devices, and methods for securing tissue using a suture having one or more protrusions |
| US11272915B2 (en) | 2012-05-07 | 2022-03-15 | Medos International Sarl | Systems, devices, and methods for securing tissue using snare assemblies and soft anchors |
| US12310573B2 (en) | 2012-05-07 | 2025-05-27 | Medos International Sàrl | Systems, devices, and methods for securing tissue using snare assemblies and soft anchors |
| US11672523B2 (en) | 2012-09-20 | 2023-06-13 | Medos International Sarl | Systems, devices, and methods for securing tissue using hard anchors |
| US9763655B2 (en) | 2012-09-20 | 2017-09-19 | Medos International Sarl | Systems, devices, and methods for securing tissue using hard anchors |
| US12369902B2 (en) | 2012-09-20 | 2025-07-29 | Medos International Sàrl | Systems, devices, and methods for securing tissue using hard anchors |
| US10695047B2 (en) | 2012-09-20 | 2020-06-30 | Medos International Sarl | Systems, devices, and methods for securing tissue using hard anchors |
| US10231727B2 (en) | 2012-09-29 | 2019-03-19 | Mitralign, Inc. | Plication lock delivery system and method of use thereof |
| US11395648B2 (en) | 2012-09-29 | 2022-07-26 | Edwards Lifesciences Corporation | Plication lock delivery system and method of use thereof |
| US9216018B2 (en) | 2012-09-29 | 2015-12-22 | Mitralign, Inc. | Plication lock delivery system and method of use thereof |
| CN103705279A (zh) * | 2012-09-29 | 2014-04-09 | 米特拉利根公司 | 折叠锁输送系统及其使用方法 |
| US10376266B2 (en) | 2012-10-23 | 2019-08-13 | Valtech Cardio, Ltd. | Percutaneous tissue anchor techniques |
| US9949828B2 (en) | 2012-10-23 | 2018-04-24 | Valtech Cardio, Ltd. | Controlled steering functionality for implant-delivery tool |
| US9730793B2 (en) | 2012-12-06 | 2017-08-15 | Valtech Cardio, Ltd. | Techniques for guide-wire based advancement of a tool |
| US10258321B2 (en) | 2012-12-27 | 2019-04-16 | Medos International Sàrl | Surgical constructs and methods for securing tissue |
| US9271716B2 (en) | 2012-12-27 | 2016-03-01 | Medos International Sàrl | Surgical constructs and methods for securing tissue |
| US11369361B2 (en) | 2012-12-27 | 2022-06-28 | Medos International Sarl | Surgical constructs and methods for securing tissue |
| US9192373B2 (en) | 2012-12-27 | 2015-11-24 | Medos International Sàrl | Surgical constructs and methods for securing tissue |
| WO2014134183A1 (fr) | 2013-02-26 | 2014-09-04 | Mitralign, Inc. | Dispositif et procédés pour réparation percutanée de valve tricuspide |
| US10251650B2 (en) | 2013-03-12 | 2019-04-09 | Sentreheart, Inc. | Tissue litigation devices and methods therefor |
| US9408608B2 (en) | 2013-03-12 | 2016-08-09 | Sentreheart, Inc. | Tissue ligation devices and methods therefor |
| US11207073B2 (en) | 2013-03-12 | 2021-12-28 | Sentreheart Llc | Tissue ligation devices and methods therefor |
| US20140276648A1 (en) * | 2013-03-14 | 2014-09-18 | Valtech Cardio, Ltd. | Guidewire feeder |
| US11534583B2 (en) * | 2013-03-14 | 2022-12-27 | Valtech Cardio Ltd. | Guidewire feeder |
| US10449333B2 (en) * | 2013-03-14 | 2019-10-22 | Valtech Cardio, Ltd. | Guidewire feeder |
| US12156981B2 (en) * | 2013-03-14 | 2024-12-03 | Edwards Lifesciences Innovation (Israel) Ltd. | Guidewire feeder |
| WO2014152503A1 (fr) | 2013-03-15 | 2014-09-25 | Mitralign, Inc. | Cathéters de translation, systèmes et leurs procédés d'utilisation |
| US12402874B2 (en) | 2013-03-15 | 2025-09-02 | Medos International Sàrl | Surgical constructs with collapsing suture loop and methods for securing tissue |
| US9737293B2 (en) | 2013-03-15 | 2017-08-22 | Medos International Sàrl | Surgical constructs with collapsing suture loop and methods for securing tissue |
| US10631848B2 (en) | 2013-03-15 | 2020-04-28 | Medos International Sàrl | Surgical constructs with collapsing suture loop and methods for securing tissue |
| US11672522B2 (en) | 2013-03-15 | 2023-06-13 | Medos International Sarl | Surgical constructs with collapsing suture loop and methods for securing tissue |
| US11523899B2 (en) | 2013-08-14 | 2022-12-13 | Mitral Valve Technologies Sarl | Coiled anchor for supporting prosthetic heart valve, prosthetic heart valve, and deployment device |
| US11229515B2 (en) | 2013-08-14 | 2022-01-25 | Mitral Valve Technologies Sarl | Replacement heart valve systems and methods |
| US12011348B2 (en) | 2013-08-14 | 2024-06-18 | Mitral Valve Technologies Sarl | Coiled anchor for supporting prosthetic heart valve, prosthetic heart valve, and deployment device |
| US10588742B2 (en) | 2013-08-14 | 2020-03-17 | Mitral Valve Technologies Sarl | Coiled anchor for supporting prosthetic heart valve, prosthetic heart valve, and deployment device |
| US10226330B2 (en) | 2013-08-14 | 2019-03-12 | Mitral Valve Technologies Sarl | Replacement heart valve apparatus and methods |
| US11234811B2 (en) | 2013-08-14 | 2022-02-01 | Mitral Valve Technologies Sarl | Replacement heart valve systems and methods |
| US11744573B2 (en) | 2013-08-31 | 2023-09-05 | Edwards Lifesciences Corporation | Devices and methods for locating and implanting tissue anchors at mitral valve commissure |
| US12396720B2 (en) | 2013-08-31 | 2025-08-26 | Edwards Lifesciences Corporation | Devices and methods for locating and implanting tissue anchors at mitral valve commissure |
| US10918373B2 (en) | 2013-08-31 | 2021-02-16 | Edwards Lifesciences Corporation | Devices and methods for locating and implanting tissue anchors at mitral valve commissure |
| US10070857B2 (en) | 2013-08-31 | 2018-09-11 | Mitralign, Inc. | Devices and methods for locating and implanting tissue anchors at mitral valve commissure |
| US10799288B2 (en) | 2013-10-31 | 2020-10-13 | Sentreheart Llc | Devices and methods for left atrial appendage closure |
| US10258408B2 (en) | 2013-10-31 | 2019-04-16 | Sentreheart, Inc. | Devices and methods for left atrial appendage closure |
| US11844566B2 (en) | 2013-10-31 | 2023-12-19 | Atricure, Inc. | Devices and methods for left atrial appendage closure |
| US10052199B2 (en) | 2014-02-21 | 2018-08-21 | Mitral Valve Technologies Sarl | Devices, systems and methods for delivering a prosthetic mitral valve and anchoring device |
| US11974914B2 (en) | 2014-02-21 | 2024-05-07 | Mitral Valve Technologies Sarl | Devices, systems and methods for delivering a prosthetic mitral valve and anchoring device |
| US10898320B2 (en) | 2014-02-21 | 2021-01-26 | Mitral Valve Technologies Sarl | Devices, systems and methods for delivering a prosthetic mitral valve and anchoring device |
| US11406493B2 (en) | 2014-09-12 | 2022-08-09 | Mitral Valve Technologies Sarl | Mitral repair and replacement devices and methods |
| US11951000B2 (en) | 2014-09-12 | 2024-04-09 | Mitral Valve Technologies Sarl | Mitral repair and replacement devices and methods |
| US10653519B2 (en) | 2014-09-12 | 2020-05-19 | Mitral Valve Technologies Sarl | Mitral repair and replacement devices and methods |
| US10016272B2 (en) | 2014-09-12 | 2018-07-10 | Mitral Valve Technologies Sarl | Mitral repair and replacement devices and methods |
| US12295834B2 (en) | 2015-02-11 | 2025-05-13 | Edwards Lifesciences Corporation | Delivery apparatuses for medical device implants |
| US11786364B2 (en) | 2015-02-11 | 2023-10-17 | Edwards Lifesciences Corporation | Delivery apparatuses for medical device implants |
| US10758341B2 (en) | 2015-02-11 | 2020-09-01 | Edwards Lifesciences Corporation | Heart valve docking devices and implanting methods |
| US10039637B2 (en) | 2015-02-11 | 2018-08-07 | Edwards Lifesciences Corporation | Heart valve docking devices and implanting methods |
| US10959734B2 (en) | 2015-03-24 | 2021-03-30 | Sentreheart Llc | Tissue ligation devices and methods therefor |
| US9936956B2 (en) | 2015-03-24 | 2018-04-10 | Sentreheart, Inc. | Devices and methods for left atrial appendage closure |
| US10130369B2 (en) | 2015-03-24 | 2018-11-20 | Sentreheart, Inc. | Tissue ligation devices and methods therefor |
| US11389167B2 (en) | 2016-02-26 | 2022-07-19 | Atricure, Inc. | Devices and methods for left atrial appendage closure |
| US10292710B2 (en) | 2016-02-26 | 2019-05-21 | Sentreheart, Inc. | Devices and methods for left atrial appendage closure |
| JP2019508204A (ja) * | 2016-05-16 | 2019-03-28 | ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． | 内視鏡縫合および縫合不全引き締め修復装置 |
| US10702274B2 (en) * | 2016-05-26 | 2020-07-07 | Edwards Lifesciences Corporation | Method and system for closing left atrial appendage |
| US20170340329A1 (en) * | 2016-05-26 | 2017-11-30 | Mitralign, Inc. | Method and System for Closing Left Atrial Appendage |
| US11540835B2 (en) | 2016-05-26 | 2023-01-03 | Edwards Lifesciences Corporation | Method and system for closing left atrial appendage |
| EP3600072A4 (fr) * | 2017-03-31 | 2021-06-02 | NeoChord, Inc. | Réparation de valvule cardiaque minimalement invasive dans un coeur battant |
| US11285003B2 (en) | 2018-03-20 | 2022-03-29 | Medtronic Vascular, Inc. | Prolapse prevention device and methods of use thereof |
| US11931261B2 (en) | 2018-03-20 | 2024-03-19 | Medtronic Vascular, Inc. | Prolapse prevention device and methods of use thereof |
| US12343257B2 (en) | 2018-03-20 | 2025-07-01 | Medtronic Vascular, Inc. | Prolapse prevention device and methods of use thereof |
| US11701228B2 (en) | 2018-03-20 | 2023-07-18 | Medtronic Vascular, Inc. | Flexible canopy valve repair systems and methods of use |
| US11026791B2 (en) | 2018-03-20 | 2021-06-08 | Medtronic Vascular, Inc. | Flexible canopy valve repair systems and methods of use |
| US12472061B2 (en) | 2019-06-07 | 2025-11-18 | Edwards Lifesciences Corporation | Systems, devices, and methods for treating heart valves |
| US11672524B2 (en) | 2019-07-15 | 2023-06-13 | Ancora Heart, Inc. | Devices and methods for tether cutting |
| US12446872B2 (en) | 2019-07-15 | 2025-10-21 | Ancora Heart, Inc. | Devices and methods for tether cutting |
| US11684473B2 (en) * | 2019-07-25 | 2023-06-27 | Innovheart S.R.L. | Device for arranging guidewires around a heart valve |
| CN113993572A (zh) * | 2019-07-25 | 2022-01-28 | 创新心有限公司 | 用于在心脏瓣膜周围布置导丝的装置 |
| US11517425B2 (en) | 2019-07-25 | 2022-12-06 | Innovheart S.R.L. | Device for implanting a prosthesis for a heart valve and assembly procedure |
| US12076233B2 (en) | 2019-07-25 | 2024-09-03 | Innovheart S.R.L. | Device for implanting a prosthesis for a heart valve and assembly procedure |
| US12485003B2 (en) | 2019-07-25 | 2025-12-02 | Innovheart S.R.L. | Device for implanting a prosthesis for a heart valve and assembly procedure |
| CN112773562A (zh) * | 2020-04-28 | 2021-05-11 | 北京领健医疗科技有限公司 | 带位置检测器的瓣膜修复系统 |
Also Published As
| Publication number | Publication date |
|---|---|
| US9750608B2 (en) | 2017-09-05 |
| US9358111B2 (en) | 2016-06-07 |
| WO2008112740A3 (fr) | 2009-01-29 |
| US20140094906A1 (en) | 2014-04-03 |
| US20080228266A1 (en) | 2008-09-18 |
| US20160317304A1 (en) | 2016-11-03 |
| US8845723B2 (en) | 2014-09-30 |
| US20150051697A1 (en) | 2015-02-19 |
| US20080228165A1 (en) | 2008-09-18 |
| WO2008112740A2 (fr) | 2008-09-18 |
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