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HK1013262A1 - Dry powder inhaler - Google Patents

Dry powder inhaler Download PDF

Info

Publication number
HK1013262A1
HK1013262A1 HK98114661A HK98114661A HK1013262A1 HK 1013262 A1 HK1013262 A1 HK 1013262A1 HK 98114661 A HK98114661 A HK 98114661A HK 98114661 A HK98114661 A HK 98114661A HK 1013262 A1 HK1013262 A1 HK 1013262A1
Authority
HK
Hong Kong
Prior art keywords
impeller
chamber
aerosolizing
housing
aerosolizing chamber
Prior art date
Application number
HK98114661A
Other languages
English (en)
French (fr)
Chinese (zh)
Other versions
HK1013262B (en
Inventor
Bernard Mecikalski Mark
Richard Williams David
Orel Thueson David
Original Assignee
Dura Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dura Pharmaceuticals, Inc. filed Critical Dura Pharmaceuticals, Inc.
Publication of HK1013262A1 publication Critical patent/HK1013262A1/en
Publication of HK1013262B publication Critical patent/HK1013262B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0013—Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0016—Details of inhalators; Constructional features thereof with inhalation check valves located downstream of the dispenser, i.e. traversed by the product
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0057—Pumps therefor
    • A61M16/0066—Blowers or centrifugal pumps

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nozzles (AREA)
  • Detergent Compositions (AREA)

Claims (9)

  1. Vorrichtung zum Aerosolisieren pulverisierter Arznei zur Inhalation, umfassend:
    ein Gehäuse (1, 201);
    eine Aerosolisierkammer (25; 235) innerhalb des Gehäuses (1; 201);
    mindestens eine Einlaßöffnung (59; 305) und mindestens eine Auslaßöffnung (61; 227), die in die Aerosolisierkammer (25; 235) hinein bzw. aus ihr herausführen;
    ein Flügelrad (31; 233) innerhalb der Aerosolisierkammer (25; 235); und
    einen Motor (43; 243), der mit dem Flügelrad (31; 233) gekoppelt ist; dadurch gekennzeichnet, daß das Flügelrad (31; 233) allseitig eng in die Aerosolisierkammer (25; 235) eingepaßt ist und die Auslaßöffnung (61; 227) die Front der Aerosolisierkammer (25; 235) durchsetzt.
  2. Vorrichtung zum Aerosolisieren pulverförmiger Arznei zur Inhalation, umfassend:
    ein Gehäuse (1, 201);
    eine Aerosolisierkammer (25; 235) innerhalb des Gehäuses (1; 201);
    mindestens eine Einlaßöffnung (59; 305) und mindestens eine Auslaßöffnung (61; 227), die in die Aerosolisierkammer (25; 235) hinein bzw. aus ihr herausführen;
    ein Flügelrad (31; 233) innerhalb der Aerosolisierkammer (25; 235); und
    einen Motor (43; 243), der mit dem Flügelrad (31; 233) gekoppelt ist; dadurch gekennzeichnet, daß das Flügelrad (31; 233) eng in die Aerosolisierkammer (25; 235) eingepaßt ist und Flügel (37) aufweist, die sich von seiner Drehachse radial nach außen erstrecken.
  3. Vorrichtung zum Aerosolisieren pulverisierter Arznei zur Inhalation, umfassend:
    ein Gehäuse (1, 201);
    eine Aerosolisierkammer (25; 235) innerhalb des Gehäuses (1; 201);
    mindestens eine Einlaßöffnung (59; 305) und mindestens eine Auslaßöffnung (61; 227), die in die Aerosolisierkammer (25; 235) hinein bzw. aus ihr herausführen;
    ein Flügelrad (31; 233) innerhalb der Aerosolisierkammer (25; 235); und
    einen Motor (43; 243), der mit dem Flügelrad (31; 233) gekoppelt ist; dadurch gekennzeichnet, daß die Aerosolisierkammer (25; 235) eine Vorderwand und eine Rückwand (11; 29; 225; 207) aufweist, die an eine flache Umfangswand (30; 208) angrenzen, und daß das Flügelrad (31; 233) eng in die Aerosolisierkammer (25; 235) eingepaßt ist.
  4. Vorrichtung nach Anspruch 1, 2 oder 3, bei der die Breite des Flügelrads (31; 233) sich vom vorderen Teil zum hinteren Teil der Aerosolisierkammer (25; 235) erstreckt.
  5. Vorrichtung nach Anspruch 1, 2 oder 3, bei der die Auslaßöffnung (61; 227) parallel zu der Drehachse des Flügelrads (31; 233) verläuft.
  6. Vorrichtung nach Anspruch 1, 2 oder 3, bei der das Flügelrad (223) zwei oder mehr Flügel aufweist.
  7. Vorrichtung nach Anspruch 1, 2 oder 3, bei der die Aerosolisierkammer (25; 235) scheibenförmig ausgebildet ist.
  8. Vorrichtung nach Anspruch 6, bei dem die Flügel des Flügelrads (233) flache Flügel sind.
  9. Vorrichtung nach Anspruch 1, 2 oder 3, bei der der Durchmesser des Flügelrads größer ist als der Abstand zwischen Vorderwand und Rückwand (11, 29; 225, 207).
HK98114661.2A 1992-10-19 1993-10-12 Dry powder inhaler HK1013262B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96340992A 1992-10-19 1992-10-19
US963409 1992-10-19
PCT/US1993/009751 WO1994008552A2 (en) 1992-10-19 1993-10-12 Dry powder inhaler

Publications (2)

Publication Number Publication Date
HK1013262A1 true HK1013262A1 (en) 1999-08-20
HK1013262B HK1013262B (en) 2000-04-07

Family

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Also Published As

Publication number Publication date
SK50395A3 (en) 1995-09-13
US5577497A (en) 1996-11-26
CZ97795A3 (en) 1996-01-17
WO1994008552A3 (en) 1995-01-12
SK279327B6 (sk) 1998-10-07
TW235245B (de) 1994-12-01
GR3029732T3 (en) 1999-06-30
ATE174804T1 (de) 1999-01-15
RO113214B1 (ro) 1998-05-29
JP2912453B2 (ja) 1999-06-28
HU9501102D0 (en) 1995-06-28
EP0665759A4 (de) 1995-10-11
CA2147260C (en) 1999-04-13
RU2141849C1 (ru) 1999-11-27
AU679700B2 (en) 1997-07-10
FI951838A0 (fi) 1995-04-18
FI951838L (fi) 1995-04-18
BR9307270A (pt) 1999-06-01
ES2127837T3 (es) 1999-05-01
DE69322789T2 (de) 1999-07-01
JPH08502423A (ja) 1996-03-19
HUT70571A (en) 1995-10-30
EP0665759B1 (de) 1998-12-23
DE69322789D1 (de) 1999-02-04
NO951478D0 (no) 1995-04-19
BG99579A (bg) 1996-01-31
WO1994008552A2 (en) 1994-04-28
SK51695A3 (en) 1995-11-08
HU217917B (hu) 2000-05-28
NO951478L (no) 1995-04-19
BG61554B1 (en) 1997-12-30
CZ282964B6 (cs) 1997-11-12
KR0177265B1 (ko) 1999-04-01
CA2147260A1 (en) 1994-04-28
NO311870B1 (no) 2002-02-11
AU5328994A (en) 1994-05-09
PL308367A1 (en) 1995-07-24
EP0665759A1 (de) 1995-08-09
UA27938C2 (uk) 2000-10-16
DK0665759T3 (da) 1999-08-23
NZ257056A (en) 1996-08-27
FI951838A7 (fi) 1995-04-18
PL172758B1 (pl) 1997-11-28

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)