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ES2385088T3 - Uso de derivados de exopolisacáridos (EPS) despolimerizados sulfatados, como cicatrizantes - Google Patents

Uso de derivados de exopolisacáridos (EPS) despolimerizados sulfatados, como cicatrizantes Download PDF

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Publication number
ES2385088T3
ES2385088T3 ES05775263T ES05775263T ES2385088T3 ES 2385088 T3 ES2385088 T3 ES 2385088T3 ES 05775263 T ES05775263 T ES 05775263T ES 05775263 T ES05775263 T ES 05775263T ES 2385088 T3 ES2385088 T3 ES 2385088T3
Authority
ES
Spain
Prior art keywords
polysaccharide derivatives
sulfated
use according
derivatives
molar mass
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES05775263T
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English (en)
Spanish (es)
Inventor
Karim Senni
Farida Geuniche
Miriam Yousfi
Florence Fioretti
Gaston-Jacques Godeau
Sylvia Colliec-Jouault
Jacqueline Ratiskol
Corinne Sinquin
Gérard RAGUENES
Anthony Courtois
Jean Guezennec
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Francais de Recherche pour lExploitation de la Mer (IFREMER)
Universite Paris Descartes
Original Assignee
Institut Francais de Recherche pour lExploitation de la Mer (IFREMER)
Universite Paris Descartes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application granted granted Critical
Publication of ES2385088T3 publication Critical patent/ES2385088T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0664—Dental pulp stem cells, Dental follicle stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0666—Mesenchymal stem cells from hair follicles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
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    • C12N2500/00—Specific components of cell culture medium
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    • C12N2500/72—Undefined extracts from bacteria
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors

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  • General Engineering & Computer Science (AREA)
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ES05775263T 2004-06-14 2005-06-06 Uso de derivados de exopolisacáridos (EPS) despolimerizados sulfatados, como cicatrizantes Expired - Lifetime ES2385088T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0406405A FR2871379B1 (fr) 2004-06-14 2004-06-14 Utilisation de derives polysaccharidiques hautement sulfates et de faible masse molaire pour moduler l'angiogenese
FR0406405 2004-06-14
PCT/FR2005/001379 WO2006003290A2 (fr) 2004-06-14 2005-06-06 Derives depolymerises sulfates d'exopolysaccharides (eps) preparation et utilisations

Publications (1)

Publication Number Publication Date
ES2385088T3 true ES2385088T3 (es) 2012-07-18

Family

ID=34946349

Family Applications (2)

Application Number Title Priority Date Filing Date
ES05775288T Expired - Lifetime ES2367121T3 (es) 2004-06-14 2005-06-06 Derivados de exopolisacaridos (eps) despolimerizados sulfatados, su preparación y sus usos.
ES05775263T Expired - Lifetime ES2385088T3 (es) 2004-06-14 2005-06-06 Uso de derivados de exopolisacáridos (EPS) despolimerizados sulfatados, como cicatrizantes

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES05775288T Expired - Lifetime ES2367121T3 (es) 2004-06-14 2005-06-06 Derivados de exopolisacaridos (eps) despolimerizados sulfatados, su preparación y sus usos.

Country Status (9)

Country Link
US (5) US7833990B2 (fr)
EP (2) EP1755620B1 (fr)
JP (2) JP5148272B2 (fr)
AT (2) ATE510546T1 (fr)
AU (2) AU2005259077B2 (fr)
CA (2) CA2570199C (fr)
ES (2) ES2367121T3 (fr)
FR (1) FR2871379B1 (fr)
WO (2) WO2006003289A2 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2894147B1 (fr) * 2005-12-07 2008-02-15 Ifremer Utilisation d'un polysaccharide excrete par l'espece vibrio diabolicus a des fins de regeneration et de protection du parodonte
JP2007204396A (ja) * 2006-01-31 2007-08-16 Pias Arise Kk マトリックスメタロプロテアーゼ−９及びエンドセリン−１の産生抑制剤、並びにその産生抑制剤を配合した炎症後色素沈着の予防・改善剤、化粧料
US20110150795A1 (en) * 2008-04-15 2011-06-23 Innovactiv Inc. Cosmetic compositions comprising exopolysaccharides derived from microbial mats, and use thereof
WO2010086696A1 (fr) * 2009-01-28 2010-08-05 Therapol Polysaccharides sulfatés de faible masse moléculaire comme candidats pour une thérapie anti-angiogénique
FR2953217B1 (fr) 2009-11-27 2012-10-05 Ifremer Procede de depolymerisation de polysaccharides par broyage mecanique
CN101856658B (zh) * 2010-06-01 2011-09-07 云南大红山管道有限公司 一种长距离铁精矿管道软堵塞的疏通方法
FR2964014B1 (fr) * 2010-08-31 2013-04-05 Ifremer Nucleus enrobe d'un revetement filmogene aux proprietes antibacteriennes et cicatrisantes et procede d'obtention.
ES2390033B1 (es) * 2010-11-30 2013-10-31 Lipotec S.A. Exopolisacárido para el tratamiento y/o cuidado de la piel, mucosas, cabello y/o uñas.
JP6100451B2 (ja) * 2011-01-18 2017-03-22 ヒノキ新薬株式会社 皮膚外用剤
ES2590752T3 (es) 2011-03-18 2016-11-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Medios de diferenciación condrogénica y métodos para inducir la diferenciación condrogénica de células
ES2424294B1 (es) * 2012-03-22 2014-07-21 Lipotec, S.A. Exopolisacárido para el tratamiento y/o cuidado de la piel, mucosas, cabello y/o uñas
EP3146971A1 (fr) * 2015-09-28 2017-03-29 Institut Francais de Recherche pour l'Exploitation de la Mer (IFREMER) Dérivé d'exopolysaccharide bactérien marin anti-métastatique et leurs utilisations
KR20180104646A (ko) * 2016-01-07 2018-09-21 비.지. 네게브 테크놀로지즈 앤드 애플리케이션스 리미티드, 엣 벤-구리온 유니버시티 면역관용 반응을 구축하기 위한 조성물 및 방법
JP2019530663A (ja) 2016-09-01 2019-10-24 インスティトゥート デ ビオロジア モレクラル エ セルラル−イーベーエミセーＩｎｓｔｉｔｕｔｏ Ｄｅ Ｂｉｏｌｏｇｉａ Ｍｏｌｅｃｕｌａｒ Ｅ Ｃｅｌｕｌａｒ − Ｉｂｍｃ シアノバクテリア細胞外ポリマー、組成物およびそれらの使用
BR112022027064A2 (pt) 2020-07-02 2023-03-07 Institut Francais De Rech Pour Lexploitation De La Mer Ifremer Derivados de exopolissacarídeos de bactérias marinhas e usos dos mesmos no tratamento de mucopolissacaridoses
EP4112060A1 (fr) 2021-07-01 2023-01-04 Institut Francais de Recherche pour l'Exploitation de la Mer (IFREMER) Dérivés d'exopolysaccharide he800 de faible poids moléculaire ayant des propriétés anticancéreuses et leurs utilisations
CN116731221B (zh) * 2023-06-26 2024-03-12 益得来(深圳)健康科技有限公司 一种多糖衍生物及其在制药中的用途
WO2025021972A1 (fr) * 2023-07-27 2025-01-30 Institut Francais De Recherche Pour L'exploitation De La Mer (Ifremer) Dérivé d'exopolysaccharide bactérien marin présentant des propriétés anticancéreuses et ses utilisations

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4102566A (en) * 1977-05-02 1978-07-25 Foster Grant Corporation Rimless spectacle
JPS58121799A (ja) * 1982-01-14 1983-07-20 Microbial Chem Res Found 多糖類ｍｐ−８６物質およびその製造法
IT1214609B (it) 1985-05-17 1990-01-18 Opocrin Spa Esosaminoglicani solfati depolimerizzati ad attivita'antitrombotica, fibrinolitica, antinfiammatoria, loro procedimento di preparazione e composizioni farmaceutiche che li contengono.
FR2701488B1 (fr) * 1993-02-15 1995-05-05 Ifremer Bactéries du type Alteromonas, polysaccharides produits par ces bactéries, ose contenu dans ces polysaccharides et applications.
US6255296B1 (en) * 1994-01-11 2001-07-03 Endomatrix, Inc. Composition and method for treating a patient susceptible to or suffering from a cardiovascular disorder or disease
JP2986376B2 (ja) * 1995-06-16 1999-12-06 株式会社ホリカワ リムレス眼鏡におけるブリッジ及びリムレス眼鏡
US5985330A (en) * 1996-08-05 1999-11-16 Coastside Bio Resources Inhibition of angiogenesis by sea cucumber fractions
US5828307A (en) * 1996-09-23 1998-10-27 Phillips Petroleum Company Hydrocarbon gas monitor desk
FR2755142B1 (fr) * 1996-10-30 1999-01-15 Ifremer Souche bacterienne marine du genre alteromonas, exopolysaccharides hydrosolubles produits par cette souche, et leurs utilisations
US5847800A (en) * 1996-12-13 1998-12-08 Tachibana; Hideaki Lens holding mechanism of spectacles
JP4051099B2 (ja) * 1997-01-31 2008-02-20 生化学工業株式会社 低分子化ヘパリン、その製造法及び医薬組成物
FR2760022B1 (fr) 1997-02-25 1999-04-30 Ifremer Souche bacterienne marine du genre vibrio, polysaccharides hydrosolubles produits par cette souche, et leurs utilisations
FR2780063B1 (fr) * 1998-06-22 2001-07-13 Ifremer Polysaccharide purifie d'alteromonas macleodii et ses utilisations
US6024445A (en) * 1998-11-04 2000-02-15 Microvision Optical, Inc. Single point attachment of bridge and temples to eyeglass lenses
IT1302534B1 (it) * 1998-12-21 2000-09-05 Fidia Advanced Biopolymers Srl Composizioni iniettabili, biocompatibili e biodegradabili comprendentialmeno un derivato dell'acido ialuronico, cellule condrogeniche, per
FR2797768B1 (fr) 1999-09-01 2003-06-13 Ifremer Utilisation d'un polysaccharide sulfate de bas poids moleculaire pour l'obtention d'un medicament actif contre la thrombose vasculaire
FR2811229B1 (fr) * 2000-07-04 2003-08-01 Ifremer Utilisation d'un polysaccharide excrete par l'espece vibrio diabolicus en cicatrisation osseuse
CN1671744A (zh) * 2002-06-18 2005-09-21 格利考斯2000有限公司 低分子量过硫酸化多糖
US7736636B2 (en) * 2003-02-12 2010-06-15 Shaker Mousa Method for treating occlusive vascular diseases & wound healing

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EP1755620A2 (fr) 2007-02-28
WO2006003290A2 (fr) 2006-01-12
ES2367121T3 (es) 2011-10-28
US20070259833A1 (en) 2007-11-08
JP2008502763A (ja) 2008-01-31
CA2570199C (fr) 2013-08-06
ATE540685T1 (de) 2012-01-15
CA2570224C (fr) 2015-08-04
FR2871379B1 (fr) 2006-09-29
US20110245199A1 (en) 2011-10-06
AU2005259078A2 (en) 2006-01-12
CA2570199A1 (fr) 2006-01-12
AU2005259078B2 (en) 2011-03-31
JP5148272B2 (ja) 2013-02-20
US8598142B2 (en) 2013-12-03
AU2005259077A1 (en) 2006-01-12
WO2006003290A3 (fr) 2006-05-04
AU2005259078A1 (en) 2006-01-12
EP1765366A2 (fr) 2007-03-28
US20150344848A1 (en) 2015-12-03
ATE510546T1 (de) 2011-06-15
JP5154221B2 (ja) 2013-02-27
EP1755620B1 (fr) 2011-05-25
US20080131472A1 (en) 2008-06-05
EP1765366B1 (fr) 2012-01-11
FR2871379A1 (fr) 2005-12-16
WO2006003289A2 (fr) 2006-01-12
US10105393B2 (en) 2018-10-23
JP2008502762A (ja) 2008-01-31
US9125883B2 (en) 2015-09-08
CA2570224A1 (fr) 2006-01-12
WO2006003289A3 (fr) 2006-05-04
US20140037597A1 (en) 2014-02-06
AU2005259077B2 (en) 2011-01-20
US7833990B2 (en) 2010-11-16

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