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EP0991774A4 - METHOD FOR INCREASING SECRETION OF PROTEINS IN EUKARYOTIC HOST CELLS - Google Patents

METHOD FOR INCREASING SECRETION OF PROTEINS IN EUKARYOTIC HOST CELLS

Info

Publication number
EP0991774A4
EP0991774A4 EP98933141A EP98933141A EP0991774A4 EP 0991774 A4 EP0991774 A4 EP 0991774A4 EP 98933141 A EP98933141 A EP 98933141A EP 98933141 A EP98933141 A EP 98933141A EP 0991774 A4 EP0991774 A4 EP 0991774A4
Authority
EP
European Patent Office
Prior art keywords
proteins
host cells
eukaryotic host
increasing secretion
secretion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98933141A
Other languages
German (de)
French (fr)
Other versions
EP0991774A1 (en
Inventor
David I Meyer
Frank Becker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California Berkeley
University of California San Diego UCSD
Original Assignee
University of California Berkeley
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California Berkeley, University of California San Diego UCSD filed Critical University of California Berkeley
Publication of EP0991774A1 publication Critical patent/EP0991774A1/en
Publication of EP0991774A4 publication Critical patent/EP0991774A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP98933141A 1997-07-03 1998-07-02 METHOD FOR INCREASING SECRETION OF PROTEINS IN EUKARYOTIC HOST CELLS Withdrawn EP0991774A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5172197P 1997-07-03 1997-07-03
US51721P 1997-07-03
PCT/US1998/013870 WO1999001565A1 (en) 1997-07-03 1998-07-02 Method for increasing secretion of proteins in eukaryotic host cells

Publications (2)

Publication Number Publication Date
EP0991774A1 EP0991774A1 (en) 2000-04-12
EP0991774A4 true EP0991774A4 (en) 2005-04-06

Family

ID=21972974

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98933141A Withdrawn EP0991774A4 (en) 1997-07-03 1998-07-02 METHOD FOR INCREASING SECRETION OF PROTEINS IN EUKARYOTIC HOST CELLS

Country Status (5)

Country Link
EP (1) EP0991774A4 (en)
JP (1) JP2002507894A (en)
AU (1) AU744484B2 (en)
CA (1) CA2295310A1 (en)
WO (1) WO1999001565A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001064947A1 (en) * 2000-03-01 2001-09-07 Nippi, Incorporated Substrate for detecting herpes virus protease and process for producing the same
CN101605887B (en) * 2006-05-16 2012-09-05 协和发酵麒麟株式会社 High secretion production method of protein
WO2014157429A1 (en) * 2013-03-26 2014-10-02 株式会社 ニッピ Method for producing protein

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *
See also references of WO9901565A1 *

Also Published As

Publication number Publication date
WO1999001565A9 (en) 1999-04-22
WO1999001565A1 (en) 1999-01-14
EP0991774A1 (en) 2000-04-12
AU744484B2 (en) 2002-02-28
JP2002507894A (en) 2002-03-12
CA2295310A1 (en) 1999-01-14
AU8287398A (en) 1999-01-25

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20000126

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 20050221

RIC1 Information provided on ipc code assigned before grant

Ipc: 7C 07K 14/705 B

Ipc: 7C 07K 14/47 B

Ipc: 7C 12N 15/85 B

Ipc: 7C 12N 15/81 B

Ipc: 7C 12P 21/02 B

Ipc: 7C 12N 15/00 B

Ipc: 7C 12N 5/10 B

Ipc: 7C 12N 5/06 B

Ipc: 7C 12N 5/02 B

Ipc: 7C 12N 5/00 B

Ipc: 7C 12P 21/06 A

17Q First examination report despatched

Effective date: 20050719

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20070315