EP0776200A4 - Composition and method for protection against drug dependency - Google Patents
Composition and method for protection against drug dependencyInfo
- Publication number
- EP0776200A4 EP0776200A4 EP95929519A EP95929519A EP0776200A4 EP 0776200 A4 EP0776200 A4 EP 0776200A4 EP 95929519 A EP95929519 A EP 95929519A EP 95929519 A EP95929519 A EP 95929519A EP 0776200 A4 EP0776200 A4 EP 0776200A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- composition
- protection against
- against drug
- drug dependency
- dependency
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C229/50—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms being part of the same condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/30—Unsaturated compounds
- C07C62/38—Unsaturated compounds containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/18—All rings being cycloaliphatic the ring system containing six carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Addiction (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28995794A | 1994-08-12 | 1994-08-12 | |
| US289957 | 1994-08-12 | ||
| US33734994A | 1994-11-10 | 1994-11-10 | |
| US337349 | 1994-11-10 | ||
| US496642 | 1995-06-29 | ||
| US08/496,642 US5661184A (en) | 1994-08-12 | 1995-06-29 | Psychiatric agents |
| PCT/US1995/010317 WO1996004900A1 (en) | 1994-08-12 | 1995-08-14 | Composition and method for protection against drug dependency |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP0776200A1 EP0776200A1 (en) | 1997-06-04 |
| EP0776200A4 true EP0776200A4 (en) | 2001-01-17 |
Family
ID=27403948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP95929519A Withdrawn EP0776200A4 (en) | 1994-08-12 | 1995-08-14 | Composition and method for protection against drug dependency |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0776200A4 (en) |
| JP (1) | JP3618104B2 (en) |
| AU (1) | AU3325095A (en) |
| CA (1) | CA2195779A1 (en) |
| WO (1) | WO1996004900A1 (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA969485B (en) * | 1995-11-16 | 1998-05-12 | Lilly Co Eli | Excitatory amino acid receptor antagonists. |
| KR19990067598A (en) * | 1995-11-16 | 1999-08-25 | 피터 지. 스트링거 | Excitatory amino acid derivatives |
| CN1202103A (en) * | 1995-11-16 | 1998-12-16 | 伊莱利利公司 | Excitatory amino acid receptor antagonists |
| GB9605429D0 (en) * | 1995-11-16 | 1996-05-15 | Lilly Co Eli | Excitatory amino acid receptor antagonists |
| US5912248A (en) * | 1995-11-16 | 1999-06-15 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
| US5688826A (en) * | 1995-11-16 | 1997-11-18 | Eli Lilly And Company | Excitatory amino acid derivatives |
| ZA983930B (en) * | 1997-05-14 | 1999-11-08 | Lilly Co Eli | Excitatory amino acid receptor modulators. |
| JP4192331B2 (en) | 1999-04-16 | 2008-12-10 | 住友化学株式会社 | Process for producing optically active 2-oxobicyclo [3.1.0] hexane-6-carboxylic acid derivative |
| WO2019025931A1 (en) | 2017-07-31 | 2019-02-07 | Novartis Ag | Use of mavoglurant in the reduction of cocaine use or in preventing relapse into cocaine use |
-
1995
- 1995-08-14 WO PCT/US1995/010317 patent/WO1996004900A1/en not_active Ceased
- 1995-08-14 AU AU33250/95A patent/AU3325095A/en not_active Abandoned
- 1995-08-14 EP EP95929519A patent/EP0776200A4/en not_active Withdrawn
- 1995-08-14 CA CA002195779A patent/CA2195779A1/en not_active Abandoned
- 1995-08-14 JP JP50756396A patent/JP3618104B2/en not_active Expired - Fee Related
Non-Patent Citations (4)
| Title |
|---|
| MORI-OKAMOTO J., ET AL.: "Intracellular mechanisms underlying the suppression of AMPA responses by trans-APCD in cultured chick purkinje neurons", MOLECULAR AND CELLULAR NEUROSCIENCES, vol. 4, no. 4, 1993, pages 375 - 386, XP000943572 * |
| See also references of WO9604900A1 * |
| TASCHENBERGER H., ET AL.: "Effect of a metabotropic glutamate agonist, trans-ACPD, on cortical epileptiform activity", NEUROREPORT, vol. 3, no. 7, 1992, pages 629 - 632, XP000943585 * |
| TIZZANO J. P. ET AL.: "Intracerebral 1S, 3R-1-aminocyclopenane-1,3-dicarboxylic acid (1S-3R, ACPD) produces limbic seizures that are not blocked by ionotropic glutamate receptor antagonists", NEUROSCIENCE LETTERS, vol. 162, no. 1-2, 1993, pages 12 - 16, XP000943579 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996004900A1 (en) | 1996-02-22 |
| JPH10504038A (en) | 1998-04-14 |
| AU3325095A (en) | 1996-03-07 |
| CA2195779A1 (en) | 1996-02-22 |
| JP3618104B2 (en) | 2005-02-09 |
| EP0776200A1 (en) | 1997-06-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 19970208 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI MC NL PT SE |
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| AX | Request for extension of the european patent |
Free format text: LT PAYMENT 970208;LV PAYMENT 970208;SI PAYMENT 970208 |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20001204 |
|
| AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI MC NL PT SE |
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| 17Q | First examination report despatched |
Effective date: 20030117 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20040821 |
|
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: WD Ref document number: 1013959 Country of ref document: HK |