[go: up one dir, main page]

DK1049717T3 - Antistoffer mod human IL-2 - Google Patents

Antistoffer mod human IL-2

Info

Publication number
DK1049717T3
DK1049717T3 DK99904780T DK99904780T DK1049717T3 DK 1049717 T3 DK1049717 T3 DK 1049717T3 DK 99904780 T DK99904780 T DK 99904780T DK 99904780 T DK99904780 T DK 99904780T DK 1049717 T3 DK1049717 T3 DK 1049717T3
Authority
DK
Denmark
Prior art keywords
antibodies
human
Prior art date
Application number
DK99904780T
Other languages
Danish (da)
English (en)
Inventor
Maurcie Kent Gately
David Howard Presky
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22106938&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1049717(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK1049717T3 publication Critical patent/DK1049717T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK99904780T 1998-01-23 1999-01-15 Antistoffer mod human IL-2 DK1049717T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7233398P 1998-01-23 1998-01-23
PCT/EP1999/000202 WO1999037682A2 (fr) 1998-01-23 1999-01-15 Anticorps contre il-12 humaine

Publications (1)

Publication Number Publication Date
DK1049717T3 true DK1049717T3 (da) 2007-07-30

Family

ID=22106938

Family Applications (2)

Application Number Title Priority Date Filing Date
DK07005606.4T DK1818343T3 (da) 1998-01-23 1999-01-15 Antistoffer mod humant IL-12
DK99904780T DK1049717T3 (da) 1998-01-23 1999-01-15 Antistoffer mod human IL-2

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK07005606.4T DK1818343T3 (da) 1998-01-23 1999-01-15 Antistoffer mod humant IL-12

Country Status (18)

Country Link
US (1) US6225117B1 (fr)
EP (2) EP1818343B1 (fr)
JP (3) JP4481489B2 (fr)
KR (1) KR100764256B1 (fr)
CN (2) CN100374466C (fr)
AR (2) AR014459A1 (fr)
AT (2) ATE357459T1 (fr)
AU (1) AU759624B2 (fr)
BR (1) BR9907743A (fr)
CA (1) CA2318052C (fr)
CY (2) CY1106594T1 (fr)
DE (1) DE69935574T2 (fr)
DK (2) DK1818343T3 (fr)
ES (2) ES2284242T3 (fr)
PT (2) PT1818343E (fr)
TR (1) TR200002145T2 (fr)
WO (1) WO1999037682A2 (fr)
ZA (1) ZA99452B (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6399379B1 (en) 1992-09-29 2002-06-04 Isis Pharmaceuticals, Inc. Antisense modulation of interleukin 12 p35 subunit expression
US20060084061A1 (en) * 2002-06-11 2006-04-20 Marcusson Eric G Methods for blocking adipocyte differentiation and triglyceride accumulation with interleukin 12 p35 inhibitors
ZA95960B (en) * 1994-03-14 1995-10-10 Genetics Inst Use of interleukin-12 antagonists in the treatment of autoimmune diseases
US6706264B1 (en) 1994-03-14 2004-03-16 Genetics Institute, Llc Use of IL-12 antagonists in the treatment of conditions promoted by an increase in levels of IFN-y
US7026456B1 (en) 1998-01-23 2006-04-11 Hoffman-La Roche, Inc. Antibodies against human IL-12
US6448081B1 (en) 2001-05-07 2002-09-10 Isis Pharmaceuticals, Inc. Antisense modulation of interleukin 12 p40 subunit expression
JP3579355B2 (ja) 1998-12-09 2004-10-20 プロテイン デザイン ラブス インコーポレイティド ヒトの乾癬を予防及び治療するための乾癬モデル動物
US6914128B1 (en) 1999-03-25 2005-07-05 Abbott Gmbh & Co. Kg Human antibodies that bind human IL-12 and methods for producing
US7883704B2 (en) 1999-03-25 2011-02-08 Abbott Gmbh & Co. Kg Methods for inhibiting the activity of the P40 subunit of human IL-12
US6939545B2 (en) * 1999-04-28 2005-09-06 Genetics Institute, Llc Composition and method for treating inflammatory disorders
CA2399387C (fr) * 2000-02-11 2015-11-03 Biogen, Inc. Polypeptide heterologue de la famille tnf
US6348316B1 (en) 2000-04-12 2002-02-19 Cedars-Sinai Medical Center Genetic testing for determining the risk of pouchitis development
US8080247B2 (en) 2000-08-07 2011-12-20 Janssen Biotech, Inc. Anti-IL-12 antibodies
US6902734B2 (en) 2000-08-07 2005-06-07 Centocor, Inc. Anti-IL-12 antibodies and compositions thereof
US7638604B2 (en) * 2001-02-23 2009-12-29 Genetics Institute, Llc Monoclonal antibodies against interleukin-22
WO2002097048A2 (fr) * 2001-05-30 2002-12-05 Centocor, Inc. Proteines derivees de l'immunoglobuline anti-p40, compositions, procedes et utilisations
KR100453877B1 (ko) 2001-07-26 2004-10-20 메덱스젠 주식회사 연쇄체화에 의한 면역 글로블린 융합 단백질의 제조 방법 및 이 방법에 의해 제조된 TNFR/Fc 융합 단백질, 상기 단백질을 코딩하는 DNA, 상기 DNA를 포함하는벡터, 및 상기 벡터에 의한 형질전환체
PT1585546E (pt) * 2002-12-30 2008-11-14 Biogen Idec Inc Antagonistas de kim-1 e sua utilização para modular o sistema imunitário
CA2550155C (fr) * 2003-12-15 2015-03-17 Dendreon Corporation Anticorps specifiques de hla-dr, compositions et methodes associees
GB0329146D0 (en) * 2003-12-16 2004-01-21 Glaxosmithkline Biolog Sa Vaccine
EP1865985B1 (fr) 2005-03-02 2010-08-25 Biogen Idec MA Inc. Anticorps kim-1 utilisés dans le traitement des états induits par th2
UA96922C2 (en) * 2005-06-30 2011-12-26 Эббот Леборейториз Il-12/p40 binding protein
TW200744634A (en) * 2006-02-21 2007-12-16 Wyeth Corp Methods of using antibodies against human IL-22
TWI417301B (zh) * 2006-02-21 2013-12-01 Wyeth Corp 對抗人類介白素-22(il-22)之抗體及其用途
US7776331B1 (en) 2007-01-16 2010-08-17 Abbott Laboratories Methods of treating plaque psoriasis
EP2527364A1 (fr) 2007-03-29 2012-11-28 Abbott Laboratories Anticorps IL-12 anti-humains cristallins
NZ602511A (en) 2008-03-18 2014-03-28 Abbvie Inc Methods for treating psoriasis
US8563697B2 (en) 2008-08-14 2013-10-22 Cephalon Australia Pty. Ltd. Anti-IL-12/IL-23 antibodies
CN104398471A (zh) * 2008-11-28 2015-03-11 Abbvie公司 稳定的抗体组合物和用于稳定其的方法
KR20120112384A (ko) * 2009-09-14 2012-10-11 애보트 게엠베하 운트 콤파니 카게 건선을 치료하는 방법
CN103275222B (zh) * 2013-05-15 2014-04-16 中山康方生物医药有限公司 一种阻断白介素12 p40功能的单克隆抗体及其编码基因和应用
CA3019164A1 (fr) 2016-03-29 2017-10-05 Janssen Biotech, Inc. Methode de traitement du psoriasis par l'augmentation de l'espacement des doses d'anticorps anti-il-12/23
TW201922780A (zh) * 2017-09-25 2019-06-16 美商健生生物科技公司 以抗il12/il23抗體治療狼瘡之安全且有效之方法
WO2019220412A2 (fr) 2018-05-18 2019-11-21 Janssen Biotech, Inc. Méthode sûre et efficace de traitement du lupus avec un anticorps anti-il12/il23
FI13575Y1 (fi) 2018-09-24 2024-03-26 Janssen Biotech Inc IL12/IL23-vasta-aine käytettäväksi turvallisessa ja tehokaassa menetelmässä haavaisen paksusuolitulehduksen hoitamiseksi
CA3138241A1 (fr) 2019-05-23 2020-11-26 Janssen Biotech, Inc. Methode de traitement de maladie intestinale inflammatoire au moyen d'une polytherapie d'anticorps diriges contre il -23 et tnf alpha
EP4596046A3 (fr) 2020-05-21 2025-10-22 Janssen Biotech, Inc. Procédé de traitement d'une maladie intestinale inflammatoire avec une polythérapie d'anticorps dirigés contre il-23 et tnf alpha

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811523A (en) 1988-11-10 1998-09-22 Trinchieri; Giorgio Antibodies to natural killer stimulatory factor
US6683046B1 (en) 1989-12-22 2004-01-27 Hoffmann-La Roche Inc. Purification and characterization of cytotoxic lymphocyte maturation factor and monoclonal antibodies thereto
CA2125763C (fr) * 1993-07-02 2007-08-28 Maurice Kent Gately Homodimere p40 de l'interleukine-12
US5536657A (en) 1993-07-19 1996-07-16 Hoffmann-La Roche Inc. Recombinant DNA encoding human receptor for interleukin-12
ZA95960B (en) * 1994-03-14 1995-10-10 Genetics Inst Use of interleukin-12 antagonists in the treatment of autoimmune diseases
US7119248B1 (en) * 1994-04-12 2006-10-10 Miltenyi Biotec Gmbh Antibodies against epitopes with homology to self antigens, methods of preparation and applications thereof
US5853721A (en) * 1995-01-31 1998-12-29 Hoffmann-La Roche Inc. Antibody to interleukin-12 receptor
US5853697A (en) * 1995-10-25 1998-12-29 The United States Of America, As Represented By The Department Of Health & Human Services Methods of treating established colitis using antibodies against IL-12
US5809360A (en) * 1996-08-07 1998-09-15 Agfa Division - Bayer Corporation Cassette for storing and accessing plates within an automated plate handler
AU734758B2 (en) * 1997-04-01 2001-06-21 Sankyo Company Limited Anti-fas antibodies

Also Published As

Publication number Publication date
CN101274962A (zh) 2008-10-01
TR200002145T2 (tr) 2000-11-21
CA2318052C (fr) 2012-07-03
JP2009197008A (ja) 2009-09-03
CN100374466C (zh) 2008-03-12
ES2284242T3 (es) 2007-11-01
ATE553129T1 (de) 2012-04-15
EP1049717B1 (fr) 2007-03-21
CA2318052A1 (fr) 1999-07-29
WO1999037682A2 (fr) 1999-07-29
JP2002501085A (ja) 2002-01-15
BR9907743A (pt) 2000-10-17
EP1818343B1 (fr) 2012-04-11
DE69935574T2 (de) 2007-12-06
DK1818343T3 (da) 2012-07-16
AU759624B2 (en) 2003-04-17
ES2386262T3 (es) 2012-08-14
ZA99452B (en) 1999-07-23
CY1112927T1 (el) 2016-04-13
DE69935574D1 (de) 2007-05-03
CY1106594T1 (el) 2012-01-25
PT1818343E (pt) 2012-07-12
EP1818343A2 (fr) 2007-08-15
US6225117B1 (en) 2001-05-01
CN1288468A (zh) 2001-03-21
EP1818343A3 (fr) 2007-08-22
KR20010034315A (ko) 2001-04-25
JP4481489B2 (ja) 2010-06-16
AR061801A2 (es) 2008-09-24
WO1999037682A3 (fr) 1999-11-18
AR014459A1 (es) 2001-02-28
PT1049717E (pt) 2007-05-31
ATE357459T1 (de) 2007-04-15
KR100764256B1 (ko) 2007-10-05
AU2517799A (en) 1999-08-09
JP2013139458A (ja) 2013-07-18
EP1049717A2 (fr) 2000-11-08

Similar Documents

Publication Publication Date Title
DK1049717T3 (da) Antistoffer mod human IL-2
NO20004133D0 (no) Antistoffer mot human CD40
DE69926816D1 (de) Dental-Verbundwerkstoff
DE69926758D1 (de) Ultraschall-siegler
ID20233A (id) Komposisi oral
ID27841A (id) Turunan-turunan biaril terapeutik
ID24314A (id) Tempat umpan bersekat-sekat
DE69532664D1 (de) Zahnstocher
DE69931855D1 (de) Hautpräparat
ID26999A (id) Komposisi perawatan kulit
DE69823800D1 (de) Korsett
ID27346A (id) Peralatan pengenal suara
DE69920345D1 (de) Fräsmeissel
DE69713171D1 (de) Mundpflegezubereitung
ID21763A (id) Perawatan untuk peradangan persendian
DE69828097D1 (de) Mundpflegezusammensetzung
DE69902932D1 (de) Verpacktes spielzeug
ID20466A (id) Komposisi oral
FR2779535B1 (fr) Multiplexeur compact
DE69521906D1 (de) Zahnhygiene - präparate
KR960016349U (ko) 이쑤시개
ID17482A (id) Komposisi untuk meningkatkan kesehatan mulut
ATA196898A (de) Zahnputzkörper
ID24759A (id) Metoda untuk meningkatkan volume tulang
FR2783400B1 (fr) Mirador ambulant