ATE237346T1 - Gebrauch von galanin um nervenschäden zu reparieren - Google Patents
Gebrauch von galanin um nervenschäden zu reparierenInfo
- Publication number
- ATE237346T1 ATE237346T1 AT97932939T AT97932939T ATE237346T1 AT E237346 T1 ATE237346 T1 AT E237346T1 AT 97932939 T AT97932939 T AT 97932939T AT 97932939 T AT97932939 T AT 97932939T AT E237346 T1 ATE237346 T1 AT E237346T1
- Authority
- AT
- Austria
- Prior art keywords
- galanin
- treatment
- nerve damage
- supression
- pain
- Prior art date
Links
- 208000028389 Nerve injury Diseases 0.000 title abstract 2
- 230000008764 nerve damage Effects 0.000 title abstract 2
- 101800002068 Galanin Proteins 0.000 abstract 5
- 102000019432 Galanin Human genes 0.000 abstract 4
- SLZIZIJTGAYEKK-CIJSCKBQSA-N molport-023-220-247 Chemical compound C([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O)NC(=O)[C@H]1N(CCC1)C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)CN)[C@@H](C)O)C1=CNC=N1 SLZIZIJTGAYEKK-CIJSCKBQSA-N 0.000 abstract 4
- 230000036407 pain Effects 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 206010002091 Anaesthesia Diseases 0.000 abstract 1
- 206010036832 Prolactinoma Diseases 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 230000037005 anaesthesia Effects 0.000 abstract 1
- 238000001949 anaesthesia Methods 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000019771 cognition Effects 0.000 abstract 1
- 238000011813 knockout mouse model Methods 0.000 abstract 1
- 210000005036 nerve Anatomy 0.000 abstract 1
- 208000005877 painful neuropathy Diseases 0.000 abstract 1
- 208000030153 prolactin-producing pituitary gland adenoma Diseases 0.000 abstract 1
- 230000008929 regeneration Effects 0.000 abstract 1
- 238000011069 regeneration method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0306—Animal model for genetic diseases
- A01K2267/0312—Animal model for Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0306—Animal model for genetic diseases
- A01K2267/0318—Animal model for neurodegenerative disease, e.g. non- Alzheimer's
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/035—Animal model for multifactorial diseases
- A01K2267/0356—Animal model for processes and diseases of the central nervous system, e.g. stress, learning, schizophrenia, pain, epilepsy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Environmental Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9615551.0A GB9615551D0 (en) | 1996-07-24 | 1996-07-24 | Galanin |
| GBGB9623869.6A GB9623869D0 (en) | 1996-11-15 | 1996-11-15 | Galanin |
| PCT/GB1997/001991 WO1998003059A1 (fr) | 1996-07-24 | 1997-07-24 | Galanine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE237346T1 true ATE237346T1 (de) | 2003-05-15 |
Family
ID=26309752
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02028584T ATE457125T1 (de) | 1996-07-24 | 1997-07-24 | Verwendung eines galanin-agonisten in der herstellung eines medikaments zur verbesserung des gedächtnisses und anderer cognitiver funktionen |
| AT97932939T ATE237346T1 (de) | 1996-07-24 | 1997-07-24 | Gebrauch von galanin um nervenschäden zu reparieren |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02028584T ATE457125T1 (de) | 1996-07-24 | 1997-07-24 | Verwendung eines galanin-agonisten in der herstellung eines medikaments zur verbesserung des gedächtnisses und anderer cognitiver funktionen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20030009777A1 (fr) |
| EP (2) | EP0918455B1 (fr) |
| JP (1) | JP2000516212A (fr) |
| AT (2) | ATE457125T1 (fr) |
| AU (1) | AU3630297A (fr) |
| DE (2) | DE69739760D1 (fr) |
| DK (2) | DK1342410T3 (fr) |
| ES (2) | ES2340984T3 (fr) |
| GB (1) | GB2331301C (fr) |
| PT (2) | PT918455E (fr) |
| WO (1) | WO1998003059A1 (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2112238T1 (es) | 1996-01-24 | 1998-04-01 | Synaptic Pharma Corp | Acido nucleico. |
| US6329197B2 (en) | 1996-10-09 | 2001-12-11 | Synaptic Pharmaceutical Corporation | DNA encoding galanin GALR3 receptors and uses thereof |
| WO2003018770A2 (fr) * | 2001-08-27 | 2003-03-06 | Tularik Inc. | Oncogenes amplifies et leur implication dans le cancer |
| AU2003211562A1 (en) * | 2002-02-22 | 2003-09-09 | Takeda Chemical Industries, Ltd. | Novel dna and use thereof |
| GB0403509D0 (en) * | 2004-02-17 | 2004-03-24 | Neuro Targets Ltd | Galanin receptors and brain injury |
| JP2008517930A (ja) * | 2004-10-21 | 2008-05-29 | トランス テック ファーマ,インコーポレイテッド | GalR1のアゴニストとしてのビススルホンアミド化合物、組成物、及び使用法 |
| GB0523550D0 (en) | 2005-11-18 | 2005-12-28 | Hunter Fleming Ltd | Therapeutic uses of steroidal compounds |
| WO2008086573A1 (fr) * | 2007-01-19 | 2008-07-24 | Howard Florey Institute Of Experimental Physiology And Medicine | Utilisation de galanine dans une méthode de traitement d'états et de troubles neurodégénératifs |
| WO2009040068A2 (fr) * | 2007-09-11 | 2009-04-02 | Mondobiotech Laboratories Ag | Utilisation d'un peptide en tant qu'agent thérapeutique |
| CA2699220A1 (fr) * | 2008-09-09 | 2010-03-18 | Mondobiotech Laboratories Ag | Utilisation d'un peptide en tant qu'agent therapeutique |
| ES2883838A1 (es) * | 2020-06-04 | 2021-12-09 | Univ Malaga | Prevencion y/o tratamiento del deterioro cognitivo asociado a sindromes de demencia |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992012997A1 (fr) * | 1991-01-16 | 1992-08-06 | The General Hospital Corporation | Galanine humaine |
| AU1462692A (en) * | 1991-02-25 | 1992-09-15 | Board Of Regents Of The University Of Washington, The | Methods for detecting galanin antagonists |
| CA2105572A1 (fr) * | 1991-03-06 | 1992-09-07 | Helen F. Evans | Galanine humaine, clones d'adnc codant pour la galanine humaine et methode de production de galanine humaine |
| SE9101472D0 (sv) * | 1991-05-15 | 1991-05-15 | Trion Forskning & Utveckling | Galanin antagonist |
| JPH06172387A (ja) * | 1992-12-11 | 1994-06-21 | Aibaitsu Kk | 合成ペプチド誘導体 |
| US6225282B1 (en) * | 1996-01-05 | 2001-05-01 | Genentech, Inc. | Treatment of hearing impairments |
| ES2112238T1 (es) * | 1996-01-24 | 1998-04-01 | Synaptic Pharma Corp | Acido nucleico. |
-
1997
- 1997-07-24 DK DK02028584.7T patent/DK1342410T3/da active
- 1997-07-24 DE DE69739760T patent/DE69739760D1/de not_active Expired - Lifetime
- 1997-07-24 DE DE69721005T patent/DE69721005T2/de not_active Expired - Lifetime
- 1997-07-24 JP JP10506711A patent/JP2000516212A/ja not_active Ceased
- 1997-07-24 US US09/230,463 patent/US20030009777A1/en not_active Abandoned
- 1997-07-24 EP EP97932939A patent/EP0918455B1/fr not_active Expired - Lifetime
- 1997-07-24 AU AU36302/97A patent/AU3630297A/en not_active Abandoned
- 1997-07-24 WO PCT/GB1997/001991 patent/WO1998003059A1/fr not_active Ceased
- 1997-07-24 ES ES02028584T patent/ES2340984T3/es not_active Expired - Lifetime
- 1997-07-24 PT PT97932939T patent/PT918455E/pt unknown
- 1997-07-24 GB GB9901264A patent/GB2331301C/en not_active Expired - Fee Related
- 1997-07-24 AT AT02028584T patent/ATE457125T1/de not_active IP Right Cessation
- 1997-07-24 PT PT02028584T patent/PT1342410E/pt unknown
- 1997-07-24 AT AT97932939T patent/ATE237346T1/de not_active IP Right Cessation
- 1997-07-24 ES ES97932939T patent/ES2196349T3/es not_active Expired - Lifetime
- 1997-07-24 EP EP02028584A patent/EP1342410B1/fr not_active Expired - Lifetime
- 1997-07-24 DK DK97932939T patent/DK0918455T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| PT918455E (pt) | 2003-09-30 |
| EP1342410A3 (fr) | 2003-12-10 |
| EP0918455B1 (fr) | 2003-04-16 |
| GB2331301A (en) | 1999-05-19 |
| DK0918455T3 (da) | 2003-08-04 |
| EP1342410A2 (fr) | 2003-09-10 |
| AU3630297A (en) | 1998-02-10 |
| DK1342410T3 (da) | 2010-05-31 |
| GB9901264D0 (en) | 1999-03-10 |
| ATE457125T1 (de) | 2010-02-15 |
| ES2340984T3 (es) | 2010-06-14 |
| EP0918455A1 (fr) | 1999-06-02 |
| US20030009777A1 (en) | 2003-01-09 |
| EP1342410B1 (fr) | 2010-02-10 |
| GB2331301C (en) | 2005-05-22 |
| PT1342410E (pt) | 2010-05-11 |
| DE69721005D1 (de) | 2003-05-22 |
| DE69739760D1 (de) | 2010-03-25 |
| ES2196349T3 (es) | 2003-12-16 |
| JP2000516212A (ja) | 2000-12-05 |
| WO1998003059A1 (fr) | 1998-01-29 |
| DE69721005T2 (de) | 2004-06-09 |
| GB2331301B (en) | 2001-02-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0918455 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |