NO875299L - Insulinpreparat for ikke-paranteral administrasjon. - Google Patents

Insulinpreparat for ikke-paranteral administrasjon.

Info

Publication number: NO875299L
Authority: NO; Norway
Prior art keywords: pct; insulin; insulin preparation; sec; possibly
Prior art date: 1986-04-18

Application number

NO875299A

Other languages

English (en)

Norwegian (no)

Other versions

NO875299D0 (no

Inventor

Per Baschmidt

Finn Benned Hansen

Bente Rose Johansen

Original Assignee

Nordisk Gentofte

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-04-18

Filing date

1987-12-17

Publication date

1987-12-17

1987-12-17 Application filed by Nordisk Gentofte filed Critical Nordisk Gentofte

1987-12-17 Publication of NO875299L publication Critical patent/NO875299L/no

1987-12-17 Publication of NO875299D0 publication Critical patent/NO875299D0/no

Links

NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 8
102000004877 Insulin Human genes 0.000 title abstract 5
108090001061 Insulin Proteins 0.000 title abstract 5
229940125396 insulin Drugs 0.000 title abstract 4
238000002360 preparation method Methods 0.000 title abstract 2
238000010521 absorption reaction Methods 0.000 abstract 1
239000000654 additive Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
239000004026 insulin derivative Substances 0.000 abstract 1
239000000178 monomer Substances 0.000 abstract 1
238000007911 parenteral administration Methods 0.000 abstract 1
230000001737 promoting effect Effects 0.000 abstract 1
238000001179 sorption measurement Methods 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Endocrinology (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Toxicology (AREA)
Zoology (AREA)
Animal Behavior & Ethology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Otolaryngology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)

NO875299A 1986-04-18 1987-12-17 Insulinpreparat for ikke-paranteral administrasjon. NO875299D0 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DK179286A DK179286D0 (da)	1986-04-18	1986-04-18	Insulinpraeparat
PCT/DK1987/000038 WO1987006137A1 (fr)	1986-04-18	1987-04-14	Preparation d'insuline pour administration non parenterale

Publications (2)

Publication Number	Publication Date
NO875299L true NO875299L (no)	1987-12-17
NO875299D0 NO875299D0 (no)	1987-12-17

Family

ID=8108089

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO875299A NO875299D0 (no)	1986-04-18	1987-12-17	Insulinpreparat for ikke-paranteral administrasjon.

Country Status (13)

Country	Link
US (1)	US5053389A (fr)
EP (1)	EP0267208B1 (fr)
JP (1)	JPH01500116A (fr)
AT (1)	ATE66614T1 (fr)
AU (1)	AU598543B2 (fr)
CA (1)	CA1283358C (fr)
DE (1)	DE3772521D1 (fr)
DK (2)	DK179286D0 (fr)
ES (1)	ES2007607A6 (fr)
FI (1)	FI87529C (fr)
IL (1)	IL82209A0 (fr)
NO (1)	NO875299D0 (fr)
WO (1)	WO1987006137A1 (fr)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2062227T3 (es) *	1989-08-21	1994-12-16	Hoffmann La Roche	Composiciones farmaceuticas no parenterales para la insulina.
IL99699A (en) *	1990-10-10	2002-04-21	Autoimmune Inc	Drug with the option of oral, intra-intestinal, or inhaled dosing for suppression of autoimmune response associated with type I diabetes
FR2686899B1 (fr) *	1992-01-31	1995-09-01	Rhone Poulenc Rorer Sa	Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
EP1607086A1 (fr) *	1993-01-29	2005-12-21	Aradigm Corporation	Procédé d'utilisation d'insuline monomère en tant que moyen servant à améliorer la réproductibilité de l'insuline inhalée
US6131567A (en) *	1993-01-29	2000-10-17	Aradigm Corporation	Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin
TW404844B (en) *	1993-04-08	2000-09-11	Oxford Biosciences Ltd	Needleless syringe
US6893664B1 (en)	1996-06-17	2005-05-17	Powderject Research Limited	Particle delivery techniques
US5948751A (en) *	1996-06-20	1999-09-07	Novo Nordisk A/S	X14-mannitol
UA65549C2 (uk) *	1996-11-05	2004-04-15	Елі Ліллі Енд Компані	Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція
CO4750643A1 (es) *	1997-06-13	1999-03-31	Lilly Co Eli	Formulacion estable de la insulina que contiene l-arginina y protamina
EP1283051B1 (fr) *	1997-06-13	2006-06-14	Eli Lilly And Company	Formulations stables à base de l'insuline
US20010007853A1 (en) *	1998-01-08	2001-07-12	Dimarchi Richard Dennis	Method for administering monomeric insulin analogs
US6350458B1 (en)	1998-02-10	2002-02-26	Generex Pharmaceuticals Incorporated	Mixed micellar drug deliver system and method of preparation
US7070799B1 (en) *	1998-02-10	2006-07-04	Generex Pharmaceuticals, Inc.	Method for administering insulin to the buccal region
US6221378B1 (en)	1998-02-10	2001-04-24	Generex Pharmaceuticals Incorporated	Mixed micellar delivery system and method of preparation
US6294153B1 (en)	1998-12-21	2001-09-25	Generex Pharmaceuticals, Inc.	Aerosol pharmaceutical formulation for pulmonary and nasal delivery
US6375975B1 (en)	1998-12-21	2002-04-23	Generex Pharmaceuticals Incorporated	Pharmaceutical compositions for buccal and pulmonary application
US6451286B1 (en)	1998-12-21	2002-09-17	Generex Pharmaceuticals Incorporated	Pharmaceutical compositions for buccal and pulmonary administration comprising an alkali metal alkyl sulfate and at least three micelle-forming compounds
US7087215B2 (en) *	1998-12-21	2006-08-08	Generex Pharmaceuticals Incorporated	Methods of administering and enhancing absorption of pharmaceutical agents
US6849263B2 (en) *	1998-12-21	2005-02-01	Generex Pharmaceutical Incorporated	Pharmaceutical compositions for buccal delivery of pain relief medications
US6350432B1 (en)	1999-03-19	2002-02-26	Generex Pharmaceuticals Incorporated	Pressurized container having an aerosolized pharmaceutical composition
CA2375914A1 (fr)	1999-06-04	2000-12-14	Delrx Pharmaceutical Corporation	Formulations comprenant des particules deshydratees d'agents pharmaceutiques et leur procede de preparation
GB2355009A (en) *	1999-07-30	2001-04-11	Univ Glasgow	Peptides conjugated to bile acids/salts
AU2001261024A1 (en)	2000-04-12	2001-10-30	Delta Biotechnology Limited	Albumin fusion proteins
US8061006B2 (en) *	2001-07-26	2011-11-22	Powderject Research Limited	Particle cassette, method and kit therefor
EP2277910A1 (fr)	2001-12-21	2011-01-26	Human Genome Sciences, Inc.	Protéines de fusion d'albumine
EP1594530A4 (fr)	2003-01-22	2006-10-11	Human Genome Sciences Inc	Proteines hybrides d'albumine
US8147426B2 (en) *	2003-12-31	2012-04-03	Nipro Diagnostics, Inc.	Integrated diagnostic test system
CA2652989A1 (fr) *	2006-06-08	2007-12-13	Diabecore Medical Inc.	Oligomeres d'insuline derives
EP2134351B1 (fr)	2007-03-13	2016-04-27	Nutrition 21, Inc.	Procédés et compositions utilisés pour la libération prolongée de chrome
WO2008132224A2 (fr)	2007-04-30	2008-11-06	Novo Nordisk A/S	Procédé de déshydratation d'une composition de protéine, composition de protéine déshydratée et composition pharmaceutique contenant la protéine déshydratée
WO2009002867A2 (fr)	2007-06-26	2008-12-31	Nutrition 21, Inc.	Forme posologique à unités multiples contenant un agent thérapeutique en combinaison avec un complément alimentaire
EP2077132A1 (fr)	2008-01-02	2009-07-08	Boehringer Ingelheim Pharma GmbH & Co. KG	Dispositif distributeur, dispositif de stockage et procédé pour la distribution d'une formulation
US10011906B2 (en)	2009-03-31	2018-07-03	Beohringer Ingelheim International Gmbh	Method for coating a surface of a component
JP5763053B2 (ja)	2009-05-18	2015-08-12	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	アダプタ、吸入器具及びアトマイザ
US10016568B2 (en)	2009-11-25	2018-07-10	Boehringer Ingelheim International Gmbh	Nebulizer
EP2504051B1 (fr)	2009-11-25	2019-09-04	Boehringer Ingelheim International GmbH	Nébuliseur
AP3141A (en)	2009-11-25	2015-02-28	Boehringer Ingelheim Int	Nebulizer
JP5874724B2 (ja)	2010-06-24	2016-03-02	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	ネブライザ
CN105749253A (zh)	2011-03-01	2016-07-13	Jds治疗有限公司	用于预防和治疗糖尿病、低血糖症及相关病症的胰岛素和铬组合物
WO2012130757A1 (fr)	2011-04-01	2012-10-04	Boehringer Ingelheim International Gmbh	Appareil médical pourvu d'un récipient
US9827384B2 (en)	2011-05-23	2017-11-28	Boehringer Ingelheim International Gmbh	Nebulizer
WO2013152894A1 (fr)	2012-04-13	2013-10-17	Boehringer Ingelheim International Gmbh	Pulvérisateur comprenant des moyens de détrompage
ES2836977T3 (es)	2013-08-09	2021-06-28	Boehringer Ingelheim Int	Nebulizador
US9744313B2 (en)	2013-08-09	2017-08-29	Boehringer Ingelheim International Gmbh	Nebulizer
CN106255554B (zh)	2014-05-07	2021-05-04	勃林格殷格翰国际有限公司	容器、喷雾器及用途
ES2874029T3 (es)	2014-05-07	2021-11-04	Boehringer Ingelheim Int	Nebulizador
PE20210959A1 (es)	2014-05-07	2021-05-25	Boehringer Ingelheim Int	Nebulizador, dispositivo indicador y recipiente
CN109069532A (zh)	2016-02-11	2018-12-21	营养21有限责任公司	含铬组合物用于改善健康和健身

Family Cites Families (16)

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Publication number	Priority date	Publication date	Assignee	Title
GB1381274A (en) *	1971-01-28	1975-01-22	Nat Res Dev	Insulin derivatives
IE36225B1 (en) *	1971-01-28	1976-09-15	Nat Res Dev	Improvements relating to insulin derivatives
GB1381273A (en) *	1971-01-28	1975-01-22	Nat Res Dev	Insulin derivatives
DK135268A (fr) *	1973-02-09
US4153689A (en) *	1975-06-13	1979-05-08	Takeda Chemical Industries, Ltd.	Stable insulin preparation for nasal administration
US4164573A (en) *	1975-06-13	1979-08-14	Galinsky Alvin M	Composition and method for making a suppository for introducing a hypoglycemic agent into a mammal
GB1554157A (en) *	1975-06-13	1979-10-17	Takeda Chemical Industries Ltd	Stable insulin preparation for intra nasal administration
GB1527605A (en) *	1975-08-20	1978-10-04	Takeda Chemical Industries Ltd	Insulin preparation for intranasal administration
US4442090A (en) *	1980-11-09	1984-04-10	Kyoto Yakuhin Kogyo Kabushiki Kaisha	Absorption-promoting compounds, compositions thereof with pharmaceuticals and/or bases for rectal administration and method of use
DE3382112D1 (de) *	1982-04-30	1991-02-21	Ajinomoto Kk	Pharmazeutische zusammensetzung.
JPS58189118A (ja) *	1982-04-30	1983-11-04	Takeda Chem Ind Ltd	経鼻投与製剤
US4534894A (en) *	1982-11-17	1985-08-13	The Rockefeller University	Process for sulphation and phosphorylation of proteins and peptides
JPS59163313A (ja) *	1983-03-09	1984-09-14	Teijin Ltd	経鼻投与用ペプチドホルモン類組成物
IL68769A (en) *	1983-05-23	1986-02-28	Hadassah Med Org	Pharmaceutical compositions containing insulin for oral administration
US4746508A (en) *	1983-06-06	1988-05-24	Beth Israel Hospital Assn.	Drug administration
JPS60224616A (ja) *	1984-04-24	1985-11-09	Teijin Ltd	経鼻投与用組成物

1986
- 1986-04-18 DK DK179286A patent/DK179286D0/da not_active Application Discontinuation
1987
- 1987-04-10 CA CA000534467A patent/CA1283358C/fr not_active Expired - Lifetime
- 1987-04-13 IL IL82209A patent/IL82209A0/xx not_active IP Right Cessation
- 1987-04-14 AT AT87902450T patent/ATE66614T1/de active
- 1987-04-14 US US07/132,969 patent/US5053389A/en not_active Expired - Fee Related
- 1987-04-14 AU AU73561/87A patent/AU598543B2/en not_active Ceased
- 1987-04-14 DE DE8787902450T patent/DE3772521D1/de not_active Expired - Lifetime
- 1987-04-14 WO PCT/DK1987/000038 patent/WO1987006137A1/fr not_active Ceased
- 1987-04-14 JP JP62502696A patent/JPH01500116A/ja active Pending
- 1987-04-14 EP EP87902450A patent/EP0267208B1/fr not_active Expired - Lifetime
- 1987-04-15 ES ES8701124A patent/ES2007607A6/es not_active Expired
- 1987-12-08 DK DK642587A patent/DK160460C/da not_active IP Right Cessation
- 1987-12-16 FI FI875533A patent/FI87529C/fi not_active IP Right Cessation
- 1987-12-17 NO NO875299A patent/NO875299D0/no unknown

Also Published As

Publication number	Publication date
JPH01500116A (ja)	1989-01-19
EP0267208A1 (fr)	1988-05-18
DK179286D0 (da)	1986-04-18
IL82209A0 (en)	1987-10-30
DK642587D0 (da)	1987-12-08
ATE66614T1 (de)	1991-09-15
AU7356187A (en)	1987-11-09
FI875533L (fi)	1987-12-16
DK160460B (da)	1991-03-18
EP0267208B1 (fr)	1991-08-28
FI875533A0 (fi)	1987-12-16
DE3772521D1 (de)	1991-10-02
ES2007607A6 (es)	1989-07-01
DK642587A (da)	1987-12-08
NO875299D0 (no)	1987-12-17
CA1283358C (fr)	1991-04-23
DK160460C (da)	1991-08-26
AU598543B2 (en)	1990-06-28
WO1987006137A1 (fr)	1987-10-22
FI87529C (fi)	1993-01-25
US5053389A (en)	1991-10-01
FI87529B (fi)	1992-10-15

Publication	Publication Date	Title
DK179286D0 (da)	1986-04-18	Insulinpraeparat
PH23014A (en)	1989-03-03	Novel insulin derivatives,their use and pharmaceutical agents for the treatment of diabetes mellitus
HUP0002373A2 (hu)	2000-10-28	Glükagon antagonisták/inverz agonisták és ezeket tartalmazó gyógyászati készítmények
SE8504945L (sv)	1986-04-23	Farmaceutiska kompositioner innehallande antracyklinglykosider
AU1923088A (en)	1989-01-27	Piperazinyl derivatives of purines and isosteres thereof as hypoglycemic agents
NO904378L (no)	1991-10-01	Fremgangsmaate for fremstilling av et modifisert protein for terapeutisk anvendelse.
ATE109145T1 (de)	1994-08-15	Heterozyklische acylaminothiazolderivate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen.
DE19375061I2 (de)	2008-11-20	Hexadecylphosphocolin enthaltende arzneimittel mit antitumorwirkung.
FI881061A7 (fi)	1988-09-10	Hitaasti vapauttavia valmisteita ruoansulatuskanavan ulkopuolisesti annettaviksi ja niiden käyttö.
DE68909409D1 (de)	1993-10-28	Heilmitteldosierung zur verabreichung an fische.
NO871295D0 (no)	1987-03-27	Fremgangsmaate for fremstilling av terapeutisk aktive aminosyrederivater.
EP0177342A3 (fr)	1987-12-02	Formulations orales de protéines thérapeutiques
AU601280B2 (en)	1990-09-06	Mixed crystals of insulin and insulin derivatives, a process for the preparation of these mixed crystals, pharmaceutical agents containing these mixed crystals, and the use thereof for the treatment of diabetes mellitus
AU3024389A (en)	1989-08-24	Therapeutic agent for the prevention of intraventricular hemorrhage in premature infants
DK607885D0 (da)	1985-12-30	Medikamentpraeparatet med formindsket giftighed
DE69004532D1 (de)	1993-12-16	Topisch anzuwendende Defibrotid enthaltende Arzneizubereitungen.
BG44709A3 (bg)	1989-01-16	Метод за получаване на 9-хлор-1,5-бензотиазепинови производни
DE69015910D1 (de)	1995-02-23	Pharmazeutische Verwendung von Fettsäuren.
IT1226072B (it)	1990-12-10	Soluzioni iniettabili pronte all'uso contenenti un glicoside antraciclinico antitumorale.
ATE32882T1 (de)	1988-03-15	Phenylnonatetraensaeurederivate, ihre herstellung und pharmazeutische praeparate mit diesen derivaten.
ATE126437T1 (de)	1995-09-15	Verwendung von depogen zur behandlung von eingeschränktem blutkreislauf.
FI843695A7 (fi)	1985-03-24	Insuliini-johdannaisia, joissa B 30-asema on modifioitu, menetelmiä niiden valmistamiseksi ja niiden käyttö sekä sokeritaudin hoitoon tarkoitettuja lääkeaineita.
DE3876425D1 (de)	1993-01-14	Gesteuerte verabreichung eines heilmittels an blut.
DE3788888D1 (de)	1994-03-10	Perhydrothiazepin- und Perhydroazepinderivate, ihre Herstellung und ihre therapeutische Verwendung.
AU609435B2 (en)	1991-05-02	Prevention of bovine respiratory disease complex in cattle by administration of interferon