NO20033632L - Fremgangsmåter for bestemmelse av protein- og peptid- terminalsekvenser - Google Patents
Fremgangsmåter for bestemmelse av protein- og peptid- terminalsekvenserInfo
- Publication number
- NO20033632L NO20033632L NO20033632A NO20033632A NO20033632L NO 20033632 L NO20033632 L NO 20033632L NO 20033632 A NO20033632 A NO 20033632A NO 20033632 A NO20033632 A NO 20033632A NO 20033632 L NO20033632 L NO 20033632L
- Authority
- NO
- Norway
- Prior art keywords
- methods
- molecules
- mass
- useful
- terminal sequences
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 6
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 239000000126 substance Substances 0.000 abstract 2
- 238000004458 analytical method Methods 0.000 abstract 1
- 238000012993 chemical processing Methods 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 238000004949 mass spectrometry Methods 0.000 abstract 1
- 238000001819 mass spectrum Methods 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 230000035945 sensitivity Effects 0.000 abstract 1
- 238000012163 sequencing technique Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6872—Methods for sequencing involving mass spectrometry
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
- H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/105831—Protein or peptide standard or control [e.g., hemoglobin, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25125—Digestion or removing interfering materials
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Polyesters Or Polycarbonates (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24216500P | 2000-10-19 | 2000-10-19 | |
| US24239800P | 2000-10-19 | 2000-10-19 | |
| PCT/US2001/049491 WO2002061661A2 (fr) | 2000-10-19 | 2001-10-19 | Procedes servant a determiner des sequences terminales de proteines et de peptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20033632L true NO20033632L (no) | 2003-08-15 |
| NO20033632D0 NO20033632D0 (no) | 2003-08-15 |
Family
ID=26934884
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20033632A NO20033632D0 (no) | 2000-10-19 | 2003-08-15 | Fremgangsmåter for bestemmelse av protein- og peptid- terminalsekvenser |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US20040209251A1 (fr) |
| EP (3) | EP2479578A1 (fr) |
| JP (3) | JP4259869B2 (fr) |
| AT (1) | ATE552348T1 (fr) |
| AU (2) | AU2002253825B8 (fr) |
| CA (2) | CA2426580C (fr) |
| DK (1) | DK1358458T3 (fr) |
| ES (1) | ES2385335T3 (fr) |
| IL (5) | IL155281A0 (fr) |
| IS (1) | IS6781A (fr) |
| NO (1) | NO20033632D0 (fr) |
| PT (1) | PT1358458E (fr) |
| WO (2) | WO2002066952A2 (fr) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6379971B1 (en) | 1998-02-24 | 2002-04-30 | Target Discovery, Inc. | Methods for sequencing proteins |
| US6764817B1 (en) | 1999-04-20 | 2004-07-20 | Target Discovery, Inc. | Methods for conducting metabolic analyses |
| US6716636B1 (en) | 1999-04-20 | 2004-04-06 | Target Discovery, Inc. | Methods for sequencing proteins |
| JP4824170B2 (ja) | 1999-04-23 | 2011-11-30 | マサチューセッツ インスティテュート オブ テクノロジー | ポリマーを表記するためのシステムおよび方法 |
| US6937330B2 (en) | 1999-04-23 | 2005-08-30 | Ppd Biomarker Discovery Sciences, Llc | Disposable optical cuvette cartridge with low fluorescence material |
| US6687395B1 (en) | 1999-07-21 | 2004-02-03 | Surromed, Inc. | System for microvolume laser scanning cytometry |
| CA2419159A1 (fr) * | 2000-08-11 | 2002-02-21 | Agilix Corporation | Systemes de detection ultrasensibles |
| EP2479578A1 (fr) | 2000-10-19 | 2012-07-25 | Target Discovery, Inc. | Étiquetage des défauts de masse pour déterminer les séquences d'oligomère |
| US6787761B2 (en) | 2000-11-27 | 2004-09-07 | Surromed, Inc. | Median filter for liquid chromatography-mass spectrometry data |
| US6873915B2 (en) | 2001-08-24 | 2005-03-29 | Surromed, Inc. | Peak selection in multidimensional data |
| US20030078739A1 (en) * | 2001-10-05 | 2003-04-24 | Surromed, Inc. | Feature list extraction from data sets such as spectra |
| AU2002365271B2 (en) * | 2001-11-06 | 2008-12-11 | Agilix Corporation | Sensitive coded detection systems |
| ITMI20020396A1 (it) * | 2002-02-27 | 2003-08-27 | Gian Luigi Gianfranceschi | Procedimento per la determinazione automatica della composizione e/o della sequenza di un polimero |
| CA2484625A1 (fr) | 2002-05-09 | 2003-11-20 | Surromed, Inc. | Procedes d'alignement temporel de donnees obtenues par chromatographie liquide ou par spectrometrie de masse |
| US7508206B2 (en) * | 2002-05-20 | 2009-03-24 | Massachusetts Institute Of Technology | Method for sequence determination using NMR |
| WO2004049385A2 (fr) * | 2002-11-22 | 2004-06-10 | Caprion Pharmaceuticals, Inc. | Mise en correspondance de constellation et utilisations |
| JP3817523B2 (ja) * | 2003-02-14 | 2006-09-06 | 株式会社日立製作所 | 質量分析データ解析システム |
| JP4532874B2 (ja) * | 2003-10-07 | 2010-08-25 | キヤノン株式会社 | 質量分析可能な原子群を構成単位とする鎖状構造を有する分子に対して付加情報を付与して、情報記録コードとして利用する方法 |
| US7105806B2 (en) * | 2003-11-26 | 2006-09-12 | Applera Corporation | Method and apparatus for de-convoluting a convoluted spectrum |
| GB0329554D0 (en) * | 2003-12-22 | 2004-01-28 | Micromass Ltd | Mass spectrometer |
| US7248360B2 (en) * | 2004-04-02 | 2007-07-24 | Ppd Biomarker Discovery Sciences, Llc | Polychronic laser scanning system and method of use |
| JP4393270B2 (ja) * | 2004-05-21 | 2010-01-06 | 株式会社日立ハイテクノロジーズ | 質量分析装置および異性体分析方法 |
| JP2008519261A (ja) * | 2004-10-29 | 2008-06-05 | ターゲット ディスカバリー インク. | 重水素化グルコースを用いたグリカン分析 |
| EP1851551A2 (fr) * | 2005-02-03 | 2007-11-07 | Perkinelmer Las, Inc. | Systemes de detection ultrasensible utilisant des signaux multidimensionnels |
| CA2609802A1 (fr) * | 2005-05-27 | 2006-12-07 | Ionwerks, Inc. | Spectrometre de masse a temps de vol a mobilite ionique multifaisceau presentant des extraction ionique bipolaire et detection de zwitterions |
| CA2631515C (fr) * | 2006-02-07 | 2015-03-31 | Mds Sciex, Inc. | Reduction de bruit chimique pour spectrometrie de masse |
| DK1991694T3 (da) * | 2006-02-13 | 2016-08-01 | Fluidigm Canada Inc | Genekspressionsanalyse med grundstoftagget oligonukleotid |
| US20080319678A1 (en) * | 2006-02-15 | 2008-12-25 | University Of Virginia Patent Foundation | Mass Tagging for Quantitative Analysis of Biomolecules using 13C Labeled Phenylisocyanate |
| US7838303B2 (en) * | 2006-07-27 | 2010-11-23 | Agilent Technologies, Inc. | Peptide derivatization method to increase fragmentation information from MS/MS spectra |
| DE102006035577A1 (de) * | 2006-07-27 | 2008-01-31 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Röntgendichtes Konjugat |
| CN101809706B (zh) * | 2007-06-01 | 2015-12-09 | 珀金埃尔默健康科学股份有限公司 | 大气压离子源性能增强方法 |
| US8536520B2 (en) | 2007-08-06 | 2013-09-17 | Iroa Technologies Llc | Method for generation and use of isotopic patterns in mass spectral data of simple organisms |
| US7820964B2 (en) * | 2007-08-06 | 2010-10-26 | Metabolic Analyses, Inc | Method for generation and use of stable isotope patterns in mass spectral data |
| US7820963B2 (en) | 2007-08-06 | 2010-10-26 | Metabolic Alayses, Inc. | Method for generation and use of isotopic patterns in mass spectral data of simple organisms |
| US8969251B2 (en) | 2007-10-02 | 2015-03-03 | Methabolic Analyses, Inc. | Generation and use of isotopic patterns in mass spectral phenotypic comparison of organisms |
| US7919746B2 (en) * | 2007-10-16 | 2011-04-05 | Perkinelmer Health Sciences, Inc. | Atmospheric pressure ion source performance enhancement |
| CA2741959C (fr) * | 2008-10-29 | 2019-06-25 | Noxxon Pharma Ag | Sequencage de molecules d'acides nucleiques par spectrometrie de masse |
| CN102648312B (zh) | 2009-07-22 | 2014-03-05 | 新加坡科技研究局 | 同质量氨基酸和其它物质的区分 |
| US8153961B2 (en) * | 2009-08-31 | 2012-04-10 | Thermo Finnigan Llc | Methods for acquisition and deductive analysis of mixed fragment peptide mass spectra |
| PL390797A1 (pl) | 2010-03-22 | 2011-09-26 | Instytut Chemii Bioorganicznej Polskiej Akademii Nauk | Biblioteka kombinatoryczna, sposób otrzymywania biblioteki kombinatorycznej, sposób identyfikacji sekwencji, sposób sekwencjonowania elementów kombinatorycznych bibliotek oligonukleotydów i/lub analogów oligonukleotydów, zastosowanie łącznika do tworzenia bibliotek kombinatorycznych oraz zestaw do identyfikacji sekwencji |
| TW201207383A (en) * | 2010-06-16 | 2012-02-16 | Abbott Lab | Comparison of protein samples |
| US9046525B2 (en) * | 2010-07-30 | 2015-06-02 | California Institute Of Technology | Method of determining the oligomeric state of a protein complex |
| US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
| EP2689250A1 (fr) | 2011-03-23 | 2014-01-29 | AbbVie Inc. | Procédés et systèmes pour l'analyse d'échantillons protéiques |
| WO2012137804A1 (fr) * | 2011-04-04 | 2012-10-11 | 株式会社Jclバイオアッセイ | Procédé pour la détermination de séquence oligonucléotidique |
| WO2013098609A1 (fr) * | 2011-12-30 | 2013-07-04 | Dh Technologies Development Pte. Ltd. | Systèmes et procédés pour séquençage de peptides par spectrométrie de masse |
| US10593528B2 (en) * | 2013-09-23 | 2020-03-17 | Micromass Uk Limited | Peak assessment for mass spectrometers |
| JP2015121500A (ja) * | 2013-12-25 | 2015-07-02 | 株式会社島津製作所 | 質量分析方法及び質量分析装置 |
| EP3170006A1 (fr) | 2014-07-18 | 2017-05-24 | Thermo Finnigan LLC | Procédés de spectrométrie de masse de mélanges de protéines de polypeptides au moyen de réaction de transfert de protons |
| EP3460481B1 (fr) | 2016-01-14 | 2020-09-02 | Thermo Finnigan LLC | Procédés d'analyse spectrale descendante de masse multiplexé de mélanges de protéines ou de polypeptides |
| EP3193352A1 (fr) | 2016-01-14 | 2017-07-19 | Thermo Finnigan LLC | Procédés de caractérisation basée sur la spectrométrie de masse de molécules biologiques |
| EP3665476A4 (fr) * | 2017-08-07 | 2021-05-05 | Agency for Science, Technology and Research | Analyse et identification rapides de lipides à partir de données de chromatographie liquide-spectrométrie de masse (lc-ms) |
| EP3687652B1 (fr) * | 2017-09-26 | 2025-07-09 | Waters Technologies Corporation | Matériaux chromatographiques de haute pureté comprenant un modificateur ionisable pour la rétention d'analytes acides |
| US20190172553A1 (en) * | 2017-11-08 | 2019-06-06 | Koninklijke Philips N.V. | Using k-mers for rapid quality control of sequencing data without alignment |
| WO2019232520A1 (fr) * | 2018-06-01 | 2019-12-05 | Cerno Bioscience Llc | Analyse par spectre de masse de grosses molécules |
| BR112021002029A2 (pt) * | 2018-08-17 | 2021-05-25 | Regeneron Pharmaceuticals, Inc. | métodos para sequenciação de proteínas de novo |
| KR102648650B1 (ko) * | 2018-10-25 | 2024-03-15 | 주식회사 엘지화학 | 고분자 말단기 분석 방법 |
| CN113552204B (zh) * | 2020-04-02 | 2024-06-21 | 株式会社岛津制作所 | 质谱分析方法和质谱系统 |
| JP7249980B2 (ja) | 2020-10-26 | 2023-03-31 | 日本電子株式会社 | マススペクトル処理装置及び方法 |
| CN112505328B (zh) * | 2020-11-02 | 2024-02-13 | 武汉金开瑞生物工程有限公司 | 一种同位素标记试剂盒和标记方法 |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4351760A (en) | 1979-09-07 | 1982-09-28 | Syva Company | Novel alkyl substituted fluorescent compounds and polyamino acid conjugates |
| US4391904A (en) | 1979-12-26 | 1983-07-05 | Syva Company | Test strip kits in immunoassays and compositions therein |
| US4830010A (en) | 1986-04-04 | 1989-05-16 | Marshall Barry J | Methods for the diagnosis of gastrointestinal disorders |
| US4842701A (en) | 1987-04-06 | 1989-06-27 | Battelle Memorial Institute | Combined electrophoretic-separation and electrospray method and system |
| US4994155A (en) * | 1988-12-09 | 1991-02-19 | Learonal, Inc. | High speed tin, lead or tin/lead alloy electroplating |
| US5174962A (en) * | 1988-06-20 | 1992-12-29 | Genomyx, Inc. | Apparatus for determining DNA sequences by mass spectrometry |
| US4994165A (en) | 1989-02-16 | 1991-02-19 | Cornell Research Foundation, Inc. | Liquid junction coupling for capillary zone electrophoresis/ion spray spectrometry |
| CA1340966C (fr) * | 1989-05-19 | 2000-04-18 | Thomas R. Covey | Procede d'analyse des proteines |
| US5100778A (en) | 1989-10-03 | 1992-03-31 | Monsanto Company | Oligosaccharide sequencing |
| EP0639227A1 (fr) | 1991-05-07 | 1995-02-22 | Oxford Glycosciences (Uk) Limited | Sequen age d'oligosaccharides |
| DE69229914T2 (de) | 1991-05-21 | 2000-04-20 | Analytica Of Brandford, Inc. | Verfahren und Apparat zur Verbesserung der Sprühionisation von gelösten Stoffen |
| EP0632720B1 (fr) | 1992-03-25 | 1998-11-11 | Depomed Systems, Inc. | Formes galeniques de medicament oral a liberation prolongee a base d'hydroxyethyl-cellulose |
| ATE166158T1 (de) | 1992-07-24 | 1998-05-15 | Us Health | Peptide brauchbar als microsequezierungsstandard und verfahren zu ihrer anwendung |
| US5470753A (en) | 1992-09-03 | 1995-11-28 | Selectide Corporation | Peptide sequencing using mass spectrometry |
| US5674698A (en) | 1992-09-14 | 1997-10-07 | Sri International | Up-converting reporters for biological and other assays using laser excitation techniques |
| US5484926A (en) * | 1993-10-07 | 1996-01-16 | Agouron Pharmaceuticals, Inc. | HIV protease inhibitors |
| US6194144B1 (en) | 1993-01-07 | 2001-02-27 | Sequenom, Inc. | DNA sequencing by mass spectrometry |
| US5547835A (en) | 1993-01-07 | 1996-08-20 | Sequenom, Inc. | DNA sequencing by mass spectrometry |
| GB9310467D0 (en) | 1993-05-20 | 1993-07-07 | Oxford Glycosystems Ltd | Glycoconjugates |
| US5386832A (en) | 1993-06-11 | 1995-02-07 | New England Deaconess Hospital | Liver function breath test using aromatic amino acids |
| US5503805A (en) | 1993-11-02 | 1996-04-02 | Affymax Technologies N.V. | Apparatus and method for parallel coupling reactions |
| US6017693A (en) * | 1994-03-14 | 2000-01-25 | University Of Washington | Identification of nucleotides, amino acids, or carbohydrates by mass spectrometry |
| DE4415480C2 (de) | 1994-05-02 | 1999-09-02 | Bruker Daltonik Gmbh | Vorrichtung und Verfahren zur massenspektrometrischen Untersuchung von Substanzgemischen durch Kopplung kapillarelektrophoretischer Separation (CE) mit Elektrospray-Ionisierung (ESI) |
| JP3415682B2 (ja) | 1994-08-10 | 2003-06-09 | 株式会社日立製作所 | キャピラリー電気泳動・質量分析計 |
| US5856082A (en) | 1994-08-31 | 1999-01-05 | University Of British Columbia | Devices and methods for characterizing proteins and peptides |
| US5766891A (en) * | 1994-12-19 | 1998-06-16 | Sloan-Kettering Institute For Cancer Research | Method for molecular cloning and polynucleotide synthesis using vaccinia DNA topoisomerase |
| US6127134A (en) | 1995-04-20 | 2000-10-03 | Carnegie Mellon University | Difference gel electrophoresis using matched multiple dyes |
| US5827659A (en) | 1995-05-19 | 1998-10-27 | Perseptive Biosystems, Inc. | Methods and apparatus for sequencing polymers using mass spectrometry |
| US5625184A (en) | 1995-05-19 | 1997-04-29 | Perseptive Biosystems, Inc. | Time-of-flight mass spectrometry analysis of biomolecules |
| US5700642A (en) | 1995-05-22 | 1997-12-23 | Sri International | Oligonucleotide sizing using immobilized cleavable primers |
| US6004770A (en) | 1995-06-07 | 1999-12-21 | Arizona State University Board Of Regents | Sample presentation apparatus for mass spectrometry |
| US5872010A (en) | 1995-07-21 | 1999-02-16 | Northeastern University | Microscale fluid handling system |
| US6027890A (en) | 1996-01-23 | 2000-02-22 | Rapigene, Inc. | Methods and compositions for enhancing sensitivity in the analysis of biological-based assays |
| US5722642A (en) * | 1996-02-16 | 1998-03-03 | Bradshaw; Terry L. | Standing privacy fence with a deployable bench |
| US5800784A (en) | 1996-07-09 | 1998-09-01 | Horn; Marcus J. | Chemical sample treatment system and cassette, and methods for effecting multistep treatment process |
| NZ336769A (en) | 1997-01-15 | 2001-01-26 | Brax Group Ltd | Method of determining hybridization of a probe to a target nucleic acid |
| US5953653A (en) | 1997-01-28 | 1999-09-14 | Mediaone Group, Inc. | Method and system for preventing mobile roaming fraud |
| GB9710582D0 (en) | 1997-05-22 | 1997-07-16 | Oxford Glycosciences Uk Ltd | A method for de novo peptide sequence determination |
| US6090558A (en) | 1997-09-19 | 2000-07-18 | Genetrace Systems, Inc. | DNA typing by mass spectrometry with polymorphic DNA repeat markers |
| GB9823646D0 (en) | 1997-12-19 | 1998-12-23 | Brax Genomics Ltd | Compounds for mass spectrometry |
| US6379971B1 (en) | 1998-02-24 | 2002-04-30 | Target Discovery, Inc. | Methods for sequencing proteins |
| US6428956B1 (en) | 1998-03-02 | 2002-08-06 | Isis Pharmaceuticals, Inc. | Mass spectrometric methods for biomolecular screening |
| US5995989A (en) * | 1998-04-24 | 1999-11-30 | Eg&G Instruments, Inc. | Method and apparatus for compression and filtering of data associated with spectrometry |
| US6359111B1 (en) * | 1998-05-28 | 2002-03-19 | Neorx Corporation | Opioid receptor targeting |
| EP1105517B2 (fr) | 1998-08-25 | 2009-09-30 | University Of Washington | Analyse quantitative rapide de proteines ou de fonction proteique dans des melanges complexes |
| US6277644B1 (en) | 1999-03-22 | 2001-08-21 | Beckman Coulter, Inc. | Method for compositional tag sequencing |
| US6677114B1 (en) | 1999-04-20 | 2004-01-13 | Target Discovery, Inc. | Polypeptide fingerprinting methods and bioinformatics database system |
| IL146093A0 (en) | 1999-04-20 | 2002-07-25 | Target Discovery Inc | Method of separating a polypeptide or protein from a solution containing a plurality thereof |
| US6391649B1 (en) * | 1999-05-04 | 2002-05-21 | The Rockefeller University | Method for the comparative quantitative analysis of proteins and other biological material by isotopic labeling and mass spectroscopy |
| WO2004006831A2 (fr) | 2002-07-12 | 2004-01-22 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Methode et dispositif d'induction de processus biologiques par des micro-organismes |
| US6699846B2 (en) | 2000-03-17 | 2004-03-02 | Corixa Corporation | Mono- and disaccharides for the treatment of nitric oxide related disorders |
| EP2479578A1 (fr) | 2000-10-19 | 2012-07-25 | Target Discovery, Inc. | Étiquetage des défauts de masse pour déterminer les séquences d'oligomère |
| CA2427747A1 (fr) | 2000-10-30 | 2002-05-10 | Kalobios, Inc. | Maturation d'affinite par selection concurrentielle |
| US6875668B2 (en) | 2000-11-03 | 2005-04-05 | Advanced Micro Devices, Inc. | Notched gate structure fabrication |
| EP1334139A2 (fr) * | 2000-11-07 | 2003-08-13 | Symyx Technologies, Inc. | Ligands de pyridylamine substitues, complexes, catalyseurs et procedes pour la polymerisation, et polymeres |
| WO2002042733A2 (fr) | 2000-11-16 | 2002-05-30 | Ciphergen Biosystems, Inc. | Procede d'analyse de spectres de masse |
| AU2002243612A1 (en) | 2001-01-18 | 2002-07-30 | The Regents Of The University Of California | Minimally invasive glaucoma surgical instrument and method |
| EP1438110A4 (fr) | 2001-02-06 | 2005-01-26 | Electronic Arts Inc | Integration de donnees temps-reel dans une application de jeu |
| US6962995B2 (en) | 2002-07-10 | 2005-11-08 | E. I. Du Pont De Nemours And Company | Charge transport compositions and electronic devices made with such compositions |
| JP4116351B2 (ja) | 2002-07-16 | 2008-07-09 | ジヤトコ株式会社 | 車両の制御装置 |
| GB0216571D0 (en) | 2002-07-17 | 2002-08-28 | Celltech R&D Ltd | Chemical compounds |
| US20050147985A1 (en) | 2004-01-05 | 2005-07-07 | Applera Corporation | Mixtures of isobarically labeled analytes and fragments ions derived therefrom |
| JP2005241161A (ja) | 2004-02-27 | 2005-09-08 | Fujita Corp | 変流量変更時の消費エネルギー算出方法および省エネルギー診断方法 |
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