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Blouin, 2008 - Google Patents

Structure-function studies of the SF3 helicase domain of the adeno-associated virus type 2 non-structural proteins: Interactions with DNA

Blouin, 2008

Document ID
18030542283030811073
Author
Blouin A
Publication year

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Snippet

As a small DNA virus, AAV has evolved to encode factors critical to its life cycle within limited genomic space, 4.7 kb. This efficiency is evident in its multifunctional nonstructural proteins. The rep open reading frame (orf) encodes the AAV nonstructural proteins, which have been …
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    • C12N2750/00011—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA Viruses ssDNA Viruses
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
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