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Hendrickson et al., 2019 - Google Patents

mTOR Targeting Agents for the Treatment of Lymphoma and Leukemia

Hendrickson et al., 2019

Document ID
105826662713647118
Author
Hendrickson A
Witzig T
Kaufmann S
Publication year
Publication venue
Innovative Leukemia and Lymphoma Therapy

External Links

Snippet

This chapter summarizes results of recent studies of mammalian target of rapamycin (mTOR) inhibitors in lymphoma and leukemia. Preclinical studies established activity of rapamycin analogs against at least some subsets of human acute lymphoblastic leukemia …
Continue reading at www.taylorfrancis.com (other versions)

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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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