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Peng et al., 2025 - Google Patents

Prefrontal cortical NR2B-containing NMDA receptors are essential for spatial working memory performance

Peng et al., 2025

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Document ID
9932225200352369358
Author
Peng J
Wang G
Han Y
Qu L
Wang M
Arnsten A
Cai J
Li B
Publication year
Publication venue
Translational Psychiatry

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Abstract NR2A and NR2B are the major GluR2 subunits of N-methyl-D-aspartate (NMDA) receptor. NR2B-containing NMDA receptor was found to be exclusively expressed in post- synapses in layer III pyramidal cells of the prefrontal cortex (PFC). Many studies have …
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    • GPHYSICS
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • GPHYSICS
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/5082Supracellular entities, e.g. tissue, organisms
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    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
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