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Worakajit et al., 2025 - Google Patents

Myosin light chain kinase-mediated epithelial barrier dysfunction as a potential pathogenic mechanism of afatinib-induced diarrheas: A study in human colonoid …

Worakajit et al., 2025

Document ID
8851157385036502695
Author
Worakajit N
Satitsri S
Kitiyakara T
Muanprasat C
Publication year
Publication venue
European Journal of Pharmacology

External Links

Snippet

Diarrheas are an important adverse effect of afatinib, a tyrosine kinase inhibitor (TKI) anti- cancer drug, leading to mortality and morbidity in cancer patients with their pathophysiological mechanisms related to intestinal barrier dysfunctions being poorly …
Continue reading at www.sciencedirect.com (other versions)

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    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
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