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Sheervalilou et al., 2020 - Google Patents

A review on microRNAs' function, detection and evaluation methods, expression dysregulation mechanisms and possible applications in clinical phase as diagnostic …

Sheervalilou et al., 2020

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Document ID
6799797339934067336
Author
Sheervalilou R
Shahraki J
Shahraki O
Shirvalilou S
Ghaznavi H
Publication year
Publication venue
Razi Journal of Medical Sciences

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Snippet

MicroRNAs are small endogenous single-stranded non-protein-coding RNAs that often act as negative gene regulators at post-transcriptional level. These molecules actively participate in a wide variety of cellular events, and are involved in pathogenesis of different …
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    • C12Q1/6876—Hybridisation probes
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
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    • C12N2310/141—MicroRNAs, miRNAs
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