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Guiotto et al., 2020 - Google Patents

Human platelet lysate to substitute fetal bovine serum in hMSC expansion for translational applications: a systematic

Guiotto et al., 2020

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Document ID
665345669936619597
Author
Guiotto M
Raffoul W
Hart A
Riehle M
di Summa P
Publication year

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Background: Foetal bovine serum (FBS), is the most commonly used culture medium additive for in vitro cultures, despite its undefined composition, its potential immunogenicity and possible prion/zoonotic transmission. For these reasons, significant efforts have been …
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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