[go: up one dir, main page]

Song et al., 2018 - Google Patents

Combining mGRASP and optogenetics enables high-resolution functional mapping of descending cortical projections

Song et al., 2018

View HTML @Full View
Document ID
6436032332816478
Author
Song J
Lucaci D
Calangiu I
Brown M
Park J
Kim J
Brickley S
Chadderton P
Publication year
Publication venue
Cell reports

External Links

Snippet

We have applied optogenetics and mGRASP, a light microscopy technique that labels synaptic contacts, to map the number and strength of defined corticocollicular (CC) connections. Using mGRASP, we show that CC projections form small, medium, and large …
Continue reading at www.cell.com (HTML) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders

Similar Documents

Publication Publication Date Title
Kalmbach et al. h-Channels contribute to divergent intrinsic membrane properties of supragranular pyramidal neurons in human versus mouse cerebral cortex
Dudok et al. Recruitment and inhibitory action of hippocampal axo-axonic cells during behavior
Lazaro et al. Reduced prefrontal synaptic connectivity and disturbed oscillatory population dynamics in the CNTNAP2 model of autism
Cheng et al. Vision-dependent specification of cell types and function in the developing cortex
Tian et al. Video-based pooled screening yields improved far-red genetically encoded voltage indicators
Evans et al. Functional dissection of basal ganglia inhibitory inputs onto substantia nigra dopaminergic neurons
Livneh et al. Odor processing by adult-born neurons
Sinha et al. Cellular and circuit mechanisms shaping the perceptual properties of the primate fovea
Gentet et al. Membrane potential dynamics of GABAergic neurons in the barrel cortex of behaving mice
Vélez-Fort et al. The stimulus selectivity and connectivity of layer six principal cells reveals cortical microcircuits underlying visual processing
Little et al. Subcellular synaptic connectivity of layer 2 pyramidal neurons in the medial prefrontal cortex
Amadei et al. Dynamic corticostriatal activity biases social bonding in monogamous female prairie voles
Kerlin et al. Broadly tuned response properties of diverse inhibitory neuron subtypes in mouse visual cortex
Valero et al. Determinants of different deep and superficial CA1 pyramidal cell dynamics during sharp-wave ripples
Bloodgood et al. The activity-dependent transcription factor NPAS4 regulates domain-specific inhibition
Milior et al. Electrophysiological properties of CA1 pyramidal neurons along the longitudinal axis of the mouse hippocampus
Vishwanathan et al. Electron microscopic reconstruction of functionally identified cells in a neural integrator
Kapoor et al. Activation of raphe nuclei triggers rapid and distinct effects on parallel olfactory bulb output channels
Kikuta et al. Odorant response properties of individual neurons in an olfactory glomerular module
Kiskinis et al. All-optical electrophysiology for high-throughput functional characterization of a human iPSC-derived motor neuron model of ALS
Piscopo et al. Diverse visual features encoded in mouse lateral geniculate nucleus
Suzuki et al. Dendritic calcium spikes are clearly detectable at the cortical surface
McBride et al. Influence of claustrum on cortex varies by area, layer, and cell type
Xu et al. Primary visual cortex shows laminar‐specific and balanced circuit organization of excitatory and inhibitory synaptic connectivity
Muñoz et al. Channelrhodopsin-assisted patching: in vivo recording of genetically and morphologically identified neurons throughout the brain