[go: up one dir, main page]

Ferreira, 2008 - Google Patents

Lpl Gene in Portuguese Patients with Hypergliceridemia

Ferreira, 2008

Document ID
5701292512819200384
Author
Ferreira M
Publication year
Publication venue
PQDT-Global

External Links

Snippet

We have identified 2 unrelated hypertriglyceridemic patients carrying LPL lossof-function mutation Gly188Glu. In order to promote a first screening for some point mutations, genomic DNA was digested with a diversity of restriction endonucleases: NIa IV; Bfa I; Hinc II; Taq I; …
Continue reading at search.proquest.com (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Similar Documents

Publication Publication Date Title
Zannis et al. HDL biogenesis, remodeling, and catabolism
Favari et al. Cholesterol efflux and reverse cholesterol transport
Rousset et al. Lecithin: cholesterol acyltransferase–from biochemistry to role in cardiovascular disease
Santamarina-Fojo et al. The role of hepatic lipase in lipoprotein metabolism and atherosclerosis
Lu et al. Dietary cholesterol absorption; more than just bile
Ramasamy Recent advances in physiological lipoprotein metabolism
Zannis et al. Role of apoA-I, ABCA1, LCAT, and SR-BI in the biogenesis of HDL
Jaye et al. A novel endothelial-derived lipase that modulates HDL metabolism
Föger et al. Plasma phospholipid transfer protein: adenovirus-mediated overexpression in mice leads to decreased plasma high density lipoprotein (HDL) and enhanced hepatic uptake of phospholipids and cholesteryl esters from HDL
Vaisman et al. ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic mice
Choi et al. Endothelial lipase
Nong et al. Hepatic lipase expression in macrophages contributes to atherosclerosis in apoE-deficient and LCAT-transgenic mice
Zannis et al. Lipoproteins and atherogenesis
Ahsan et al. Role of lecithin: cholesterol acyltransferase in HDL metabolism and atherosclerosis
Albers et al. Homozygosity for a partial deletion of apoprotein AV signal peptide results in intracellular missorting of the protein and chylomicronemia in a breast-fed infant
Out et al. Adenovirus-mediated hepatic overexpression of scavenger receptor class B type I accelerates chylomicron metabolism in C57BL/6J mice
Zhao et al. Apolipoprotein E is the major physiological activator of lecithin− cholesterol acyltransferase (LCAT) on apolipoprotein B lipoproteins
Lester et al. Hepatic CEACAM1 over-expression protects against diet-induced fibrosis and inflammation in white adipose tissue
Lusis Lipoprotein metabolism: high-density lipoprotein
Dastani et al. A novel nonsense apolipoprotein AI mutation (apoA-IE136X) causes low HDL cholesterol in French Canadians
Reardon et al. In vivo studies of HDL assembly and metabolism using adenovirus-mediated transfer of ApoA-I mutants in ApoA-I-deficient mice
Freeman et al. Lipolytic and ligand-binding functions of hepatic lipase protect against atherosclerosis in LDL receptor-deficient mices⃞
Moerland et al. Atherogenic, enlarged, and dysfunctional HDL in human PLTP/apoA-I double transgenic mice
van Schie et al. Monogenetic disorders of the cholesterol metabolism and premature cardiovascular disease
Saba et al. Lipoproteins and cardiovascular diseases