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About this book
Although the importance of calcium (Ca2+) in the maintenance of cardiac contractility was recognized as early as 1880, the critical role of the ion in the contractile process in skeletal, cardiac, and smooth muscle has only been established within the last three decades.
As the complexity of the pharmacological actions of the Ca2+ channel inhibitors grows, there is a continued need to further clarify the inhibitors, both chemically and functionally.
This volume provides an update of the field based on the work presented at the 5th International Symposium on Calcium Antagonists: Pharmacology and Clinical Research. It reviews the current state of the growing area of molecular biology of Ca2+ channels. In the cardiovascular area, in addition to the well-established clinical uses of Ca2+ channel inhibitors, exciting new work pointing to an application in atherosclerosis is described. The book also includes important uses of Ca2+ antagonists in novel areas of interest such as the gastrointestinal tract, renal protection and multi-drug resistance.
As the complexity of the pharmacological actions of the Ca2+ channel inhibitors grows, there is a continued need to further clarify the inhibitors, both chemically and functionally.
This volume provides an update of the field based on the work presented at the 5th International Symposium on Calcium Antagonists: Pharmacology and Clinical Research. It reviews the current state of the growing area of molecular biology of Ca2+ channels. In the cardiovascular area, in addition to the well-established clinical uses of Ca2+ channel inhibitors, exciting new work pointing to an application in atherosclerosis is described. The book also includes important uses of Ca2+ antagonists in novel areas of interest such as the gastrointestinal tract, renal protection and multi-drug resistance.
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Table of contents (48 chapters)
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Front Matter
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Calcium Channels, The Molecular Approach
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Cardiovascular Applications of Calcium Antagonists: From Pathophysiology to Therapy
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Hypertension and Heart Failure
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Atherosclerosis
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Editors and Affiliations
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Bibliographic Information
Book Title: Calcium Antagonists
Book Subtitle: Pharmacology and Clinical Research
Editors: T. Godfraind, R. Paoletti, S. Govoni, P. M. Vanhoutte
Series Title: Medical Science Symposia Series
DOI: https://doi.org/10.1007/978-94-011-1725-8
Publisher: Springer Dordrecht
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eBook Packages: Springer Book Archive
Copyright Information: Springer Science+Business Media Dordrecht 1993
Hardcover ISBN: 978-0-7923-2259-7Published: 31 May 1993
Softcover ISBN: 978-94-010-4756-2Published: 22 January 2013
eBook ISBN: 978-94-011-1725-8Published: 14 March 2013
Series ISSN: 0928-9550
Edition Number: 1
Number of Pages: XXV, 381
Topics: Cardiology, Pharmacology/Toxicology