Overview
- Includes cutting-edge methods and protocols in the field of vaccine adjuvant research
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1494)
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About this book
This collection seeks to elucidate the practical methods necessary for successful adjuvant development, with a particular focus on the synthesis, formulation, manufacturing, and characterization aspects involved. Beginning with an overview and a case study, the book then delves into in silico design, chemical synthesis, biosynthesis, and/or purification from natural raw materials of specific adjuvant molecules, adjuvant formulation approaches, the analytical characterization of adjuvant formulations and adjuvant-containing vaccines, as well as the biological characterization of vaccine adjuvant activity, including in vitro and in vivo approaches, to measure innate and adaptive immune responses. Written in the highly successful Methods in Molecular Biology format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Practical and authoritative, Vaccine Adjuvants: Methods and Protocols aims to facilitate vaccine adjuvant product development efforts, making them more accessible, manufacturable, and better characterized.
Practical and authoritative, Vaccine Adjuvants: Methods and Protocols aims to facilitate vaccine adjuvant product development efforts, making them more accessible, manufacturable, and better characterized.
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Table of contents (26 protocols)
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Front Matter
Editors and Affiliations
Accessibility Information
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Bibliographic Information
Book Title: Vaccine Adjuvants
Book Subtitle: Methods and Protocols
Editors: Christopher B. Fox
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-6445-1
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media New York 2017
Hardcover ISBN: 978-1-4939-6443-7Published: 08 October 2016
Softcover ISBN: 978-1-4939-8202-8Published: 14 July 2018
eBook ISBN: 978-1-4939-6445-1Published: 07 October 2016
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XII, 372
Number of Illustrations: 42 b/w illustrations, 33 illustrations in colour
Topics: Immunology