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NMR of Glycoproteins

Methods and Protocols

  • Book
  • © 2025

Overview

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 2961)

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About this book

This volume explores the latest advancements in the field of Nuclear Magnetic Resonance (NMR) and discusses how new studies provide insight into the structure, conformation, dynamics, and interactions of glycoproteins. The chapters in this book covers topics such as the preparation of isotope-labeled eukaryotic glycoproteins; applications of paramagnetic NMR to dissect glycosaminoglycan-protein interactions; interactions of mucin glycoproteins; applications of NMR to decipher the interactions between viral proteins and the glycans on host cells; NMR methods to identify biomarkers based on the glycoprotein signals directly acquired from intact biofluids; and the applications of MD simulations and other computational methods to characterize the conformation and dynamics of glycoproteins. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and thorough, NMR of Glycoproteins: Methods and Protocols is a valuable resource for both new and experienced researchers who want to learn more about this important and developing field.
 

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Table of contents (12 protocols)

Editors and Affiliations

  • Chemical Glycobiology Laboratory, CIC BioGUNE, Derio- Bizkaia, Spain

    Jesús Jiménez-Barbero

  • Precision Medicine and Metabolism Lab, CIC bioGUNE, Derio, Spain

    Oscar Millet

Accessibility Information

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This PDF has been created in accordance with the PDF/UA-1 standard to enhance accessibility, including screen reader support, described non-text content (images, graphs), bookmarks for easy navigation, keyboard-friendly links and forms and searchable, selectable text. We recognize the importance of accessibility, and we welcome queries about accessibility for any of our products. If you have a question or an access need, please get in touch with us at accessibilitysupport@springernature.com. Please note that a more accessible version of this eBook is available as ePub.

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This ebook is designed with accessibility in mind, aiming to meet the ePub Accessibility 1.0 AA and WCAG 2.2 Level AA standards. It features a navigable table of contents, structured headings, and alternative text for images, ensuring smooth, intuitive navigation and comprehension. The text is reflowable and resizable, with sufficient contrast. We recognize the importance of accessibility, and we welcome queries about accessibility for any of our products. If you have a question or an access need, please get in touch with us at accessibilitysupport@springernature.com.

Bibliographic Information

  • Book Title: NMR of Glycoproteins

  • Book Subtitle: Methods and Protocols

  • Editors: Jesús Jiménez-Barbero, Oscar Millet

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-0716-4722-6

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2025

  • Hardcover ISBN: 978-1-0716-4721-9Published: 02 August 2025

  • Softcover ISBN: 978-1-0716-4724-0Due: 16 August 2026

  • eBook ISBN: 978-1-0716-4722-6Published: 01 August 2025

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: X, 210

  • Number of Illustrations: 8 b/w illustrations, 63 illustrations in colour

  • Topics: Chemistry/Food Science, general

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