Teddy Roosevelt was once given a daily dose of an artificial sweetener, prescribed by his doctor.

As part of government research, a group of young men were paid to eat standard American food—replete with food additives like borax and formaldehyde—which revealed the dangers of unregulated food. The work was led by the first FDA commissioner, Harvey Wiley, who helped end the "century of the great stomachache."

There are a few reasons why American Coke turned away from sugar in the 1980s, but none of them are related to consumer health. This Reader's Digest article breaks down the history behind Coke's recipe change, explaining why the company continues using high-fructose cough syrup.

After a 1909 pre-inauguration dinner for incoming President William Howard Taft featured possums and potatoes as the main course, Susie W. Allgood wanted to produce and market an alternative to the Teddy Roosevelt-inspired teddy bear: Billy Possum. Kids thought it looked too much like a rat.

The Poison Squad tells the story of government chemist Dr. Harvey Wiley who, determined to banish these dangerous substances from dinner tables, took on the powerful food manufacturers and their allies.

Humanity's ancestors evolved to wring more calories from sugary fruits by storing excess sugar as fat, an adaption that's culminated in many peoples' palettes preferring calorie-rich sweet. Now, the desire for sugar has both contributed to a widespread health crisis and been at the center of atrocities around the world.

Roosevelt transformed the presidency by expanding executive power beyond conventional norms, arguing that the president could act in the national interest unless expressly forbidden to do so. His energetic leadership, media use, and policy activism expanded the office's role and prestige.

Roosevelt's My Day column was launched in late 1935 and ran nearly every day until shortly before her death in 1962. It began as an account of her daily life but grew into one of the most widely read opinion columns in the country, with 4 million readers at its peak.

The US Department of Agriculture began offering eating advice in 1894 and has updated its guidance as both science and politics have evolved. In the early 20th century, its guidance emphasized recommended minimum servings of important foods; in later decades, its visual guides became more nuanced, illustrating the composition of a healthy diet and encouraging exercise.

It's generally accepted that sugar rushes are a myth, and that hyperactivity is a more psychological experience. However, there is real science behind the rare sugar crash that primarily impacts those with diabetes. Read this article to understand how historical and cultural factors have shaped sugar perceptions, and how low blood sugar can trigger shakiness, fatigue, weakness, and more in diabetes patients.

The president's casual radio addresses ditched the language of sloganeering and politiciking, intentionally framing the broadcasts as conversational explanations of current events and politics. The inaugural episode was broadcast in 1933, during the Great Depression, and outlined his plans to restore faith in the banking system.

A typical gummy vitamin contains about the same amount of sugar in a single serving as one Sour Patch candy. It's linked to the increase in pediatric overdoses for products including multivitamins and melatonin. Gummy formulations also degrade quickly, so they often include much higher levels of the product in each serving than the label advertises—boosting overdose risks due to this unchecked variability.

After Franklin D. Roosevelt won four elections, Congress moved to prevent future presidents from holding power indefinitely. Ratified in 1951, the 22nd Amendment set a firm two-term limit as a safeguard against extended presidencies.

In January 1922, the 14-year-old was the first person to receive an insulin injection to treat diabetes, just months after insulin was isolated in dogs and used to treat their induced diabetes. Thompson had an allergic response to an apparent impurity in the injection, but his second dose, 12 days later, was a success.

In 1912, after serving nearly two full terms—one elected, the other partial after stepping in as vice president—Theodore Roosevelt sought a third. He lost the Republican nomination to William Taft, then ran as a Progressive Party candidate but was ultimately defeated by Woodrow Wilson.

- Former President Theodore Roosevelt's (1858–1919)

Beginning in 1933, FDR harnessed the new medium of radio to explain policies and reassure the public during the Great Depression and World War II. His conversational fireside chats revolutionized presidential communication.

Type 2 diabetics in the US risk dying from low blood sugar, an epidemic traced to a decades-old, multi-million-dollar drug industry campaign encouraging an average blood sugar level below 7%. Contemporary research correlated such levels with reduced risk of eye, nerve, and kidney damage and increased hypoglycemia risk.

FDR contracted polio at age 39 and permanently lost the use of his legs. Eleanor Roosevelt persuaded him to stay in politics, then took on the task of maintaining his public profile—attending events, building relationships, and serving as his "eyes, ears, and legs" across the country.

Experiments dating back to the 1940s eventually led to the creation and standardization of a mixture of sugar, salt, and clean water that is now widely used globally.

J. Edgar Hoover's FBI maintained a large file on Eleanor Roosevelt, monitoring her involvement with civil rights groups, connections to progressive causes, and vocal opposition to McCarthyism. Although a formal investigation was never initiated, Hoover regarded her as a person of interest for most of her adult life.

At age 32, pitcher James “Pud” Galvin was feeling tired and decided to take "the Brown-Séquard elixir," which contained a testicular fluid from dogs and guinea pigs, believed to invigorate tired bodies. It might've worked: Galvin pitched a two-hit shutout the next day.

For centuries, Type 1 diabetes was fatal. The 1920s "discovery" of insulin netted two of its creators—Frederick Banting and his boss, John Macleod—a Nobel prize. Separately, the German doctor Georg Zuelzer synthesized an effective version of the life-saving drug years earlier but was interrupted by World War I.

In 1847, a Boston pharmacist invented a machine that automated the production of his pharmacy's medicinal lozenges and then formed the New England Confectionery Company, which later became part of the company now known as NECCO. By the late 1800s, they were producing cookies with Valentine-themed messages and eventually brought the romantic messages to their smaller lozenges, which they later called Sweethearts.