8000 proper alignment to root · Issue #120 · blab/nextflu · GitHub
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proper alignment to root #120

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@rneher

replace the current alignment algorithm with something that tolerates gaps

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  1. trvrb commented on Dec 23, 2015

    @trvrb
    Member

    Can you say more? You'd like an alignment that maintains gaps? Wouldn't numbering get very complicated in this case?

    I guess you could do an alignment that allows gaps then build the tree then remove gaps to get canonical numbering.

  2. rneher commented on Dec 23, 2015

    @rneher
    ContributorAuthor

    this refers to the sequence search in javascript. We align to root using a stupid string matching routine and then look for mutations. If the query has a gap relative to root, no proper alignment is found.

  3. trvrb commented on Sep 23, 2017

    @trvrb
    Member

    This has been resolved in the nextstrain/augur codebase.

  4. rneher commented on Sep 23, 2017

    @rneher
    ContributorAuthor

    I don't think this is resolved. It also refers to sequence search/alignment in auspice rather than augur. This should be a feature request in auspice. I did write a proper pairwise aligner a while back: https://github.com/neherlab/timetree_viewer/blob/master/js/alignPairwise.js

  5. reopened this on Sep 23, 2017
  6. trvrb commented on Sep 23, 2017

    @trvrb
    Member

    I see. Thanks Richard. Just reopened.

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