8000 Color heterogeneity · Issue #92 · nf-core/mcmicro · GitHub
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Color heterogeneity #92

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@tkcaccia

Is your feature request related to a problem? Please describe

Can you please include a standard deviation of the marker intensity inside the cell segmentation?
This value could be associated to nuclear morphology

Describe the solution you'd like

No response

Describe alternatives you've considered

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  1. SPPearce commented on Jun 29, 2025

    @SPPearce

    Hi,
    I don't understand what your comment is related to, can you please elaborate

  2. tkcaccia commented on Jun 30, 2025

    @tkcaccia
    Author

    I assume the quantification module in MCMICRO sums the intensity values of all pixels within each segmented cell. In addition to this total intensity, would it be possible to also obtain the standard deviation of pixel intensities within each cell?

  3. transferred this issue fromnf-core/moduleson Jun 30, 2025
  4. jmuhlich commented on Aug 25, 2025

    @jmuhlich
    Member

    Yes, we will add support for more statistical aggregate functions for the marker intensity metrics.

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