There are 10 ways to get from Tampa to Key Largo by train, bus, bus (Flixbus, Greyhound), car, plane, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus via Delray Beach
best- Take the train from Tampa to Delray Beach Amtraktrain
- Take the train from Delray Beach Station to Miami Airport Stationtrain
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
8h 26m$131–201Drive 293.7 mi
cheapest- Drive from Tampa to Key Largocar 293.7 mi
5h 51m$54–78Bus
- Take the bus from Tampa Bus Station to Miami Airport Stationbus FlixBus 2421 / ...
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus Greyhound US0720s
8h 40m$55–91Fly Tampa to Miami International Airport, shuttle
- Fly from Tampa (TPA) to Miami International Airport (MIA)plane TPA - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
5h 6m$752–1,232Train, bus
- Take the train from Tampa to Miami Amtrak Stationtrain Floridian
- Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largobus 301
9h 13m$150–225Bus, train
- Take the bus from Tampa Bus Station to Ft Lauderdale Broward Park & Ridebus
- Take the train from Fort Lauderdale Station to Miami Airport Stationtrain
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
11h 3m$63–93Fly Tampa to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Tampa (TPA) to Fort Lauderdale–Hollywood International Airport (FLL)plane TPA - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
5h 34m$222–432Fly Tampa to Key West International Airport, bus
- Fly from Tampa (TPA) to Key West International Airport (EYW)plane TPA - EYW
- Take the bus from Key West Airport to Key Largo Bus Stopbus
6h 49m$69–358Bus to Sarasota–Bradenton International Airport, fly to Miami International Airport, shuttle
- Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus
- Fly from Sarasota–Bradenton International Airport (SRQ) to Miami International Airport (MIA)plane SRQ - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
7h 1m$177–609Fly Saint Petersburg–Clearwater International Airport to Key West International Airport, bus
- Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane PIE - EYW
- Take the bus from Key West Airport to Key Largo Bus Stopbus
7h 18m$57–281
Tampa to Key Largo by train and bus
Comparing Your Travel Options
The cheapest way to get from Tampa to Key Largo is to drive which costs $50 - $80 and takes 5h 51m.
The fastest way to get from Tampa to Key Largo is to fly and shuttle which takes 5h 6m and costs $750 - $1,300.
No, there is no direct bus from Tampa station to Key Largo. However, there are services departing from Tampa Bus Station and arriving at Key Largo Bus Stop via Miami Airport Station. The journey, including transfers, takes approximately 8h 40m.
The distance between Tampa and Key Largo is 318 miles. The road distance is 295.4 miles.
The best way to get from Tampa to Key Largo without a car is to train and bus via Delray Beach which takes 8h 26m and costs $130 - $210.
It takes approximately 8h 26m to get from Tampa to Key Largo, including transfers.
Tampa to Key Largo bus services, operated by Flixbus USA, depart from Tampa Bus Station.
Tampa to Key Largo bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Tampa to Key Largo is 295 miles. It takes approximately 5h 51m to drive from Tampa to Key Largo.
Book your Tampa to Key Largo bus tickets online with Omio and FlixBus.
What companies run services between Tampa, FL, USA and Key Largo, FL, USA?
You can take a bus from Tampa Bus Station to Key Largo Bus Stop via Miami Airport Station in around 8h 40m.
- Website
- flybreeze.com
Flights from Tampa to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $100–270
Flights from Tampa to Key West International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $50–330
- Website
- aa.com
Flights from Tampa to Miami International Airport
- Ave. Duration
- 1h 8m
- When
- Every day
- Estimated price
- $40–290
Flights from Sarasota–Bradenton International Airport to Miami International Airport
- Ave. Duration
- 1h 3m
- When
- Every day
- Estimated price
- $65–460
- Website
- allegiantair.com
Flights from Saint Petersburg–Clearwater International Airport to Key West International Airport
- Ave. Duration
- 1h 2m
- When
- Thursday, Sunday, Wednesday, Saturday, Friday, and Monday
- Estimated price
- $35–250
- Website
- southwest.com
Flights from Tampa to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $40–310
- Website
- jetblue.com
Flights from Tampa to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 8m
- When
- Every day
- Estimated price
- $40–310
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Tampa to Delray Beach Amtrak
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $110–180
- Website
- Amtrak
Train from Tampa to Miami Amtrak Station
- Ave. Duration
- 5h 26m
- Frequency
- Once daily
- Estimated price
- $140–220
- Website
- Amtrak
- Phone
- +1 800-874-7245
- Tri-RailCustomerExperience@sfrta.fl.gov
- Website
- Tri Rail
Train from Delray Beach Station to Miami Airport Station
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- $5–9
- Website
- Tri Rail
- Weekend | Holiday
- $5
- Weekday
- $6–9
Train from Fort Lauderdale Station to Miami Airport Station
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $4–6
- Website
- Tri Rail
- Weekend | Holiday
- $5
- Weekday
- $4–6
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $10–15
- Website
- Greyhound
Bus from Tampa Bus Station to Miami Airport Station
- Ave. Duration
- 8h
- Frequency
- Once daily
- Estimated price
- $50–80
- Website
- Greyhound
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $10–15
- Website
- Greyhound
Bus from Tampa Bus Station to Ft Lauderdale Broward Park & Ride
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $45–75
- Website
- Greyhound
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $10–15
- Website
- Greyhound
Bus from Key West Airport to Key Largo Bus Stop
- Ave. Duration
- 2h 50m
- Frequency
- 3 times a day
- Estimated price
- $17–26
- Website
- Greyhound
Bus from Key West Airport to Key Largo Bus Stop
- Ave. Duration
- 2h 50m
- Frequency
- 3 times a day
- Estimated price
- $17–26
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Tampa Bus Station to Miami Airport Station
- Ave. Duration
- 6h 20m
- Frequency
- 4 times a day
- Estimated price
- $45–70
- Schedules at
- Flixbus USA
Bus from Tampa Bus Station to Sarasota Cattlemen Transfer Center
- Ave. Duration
- 1h 40m
- Frequency
- 3 times a day
- Estimated price
- $10–15
- Schedules at
- Flixbus USA
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $100–130
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $120–150
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $100–130
- Website
- Keys Shuttle
- Phone
- 305-891-3131
- Website
- Miami Dade Transit
Bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largo
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- Miami Dade Transit
- Schedules at
- World Cup Info: Miami Dade Transit
- Adult
- $3
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There are 320+ hotels available in Key Largo.