There are 2 ways to get from Port Orange to Lake City by bus (Flixbus, Greyhound) or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Comparing Your Travel Options
The cheapest way to get from Port Orange to Lake City is to drive which costs $24 - $40 and takes 2h 48m.
The fastest way to get from Port Orange to Lake City is to drive which takes 2h 48m and costs $24 - $40.
No, there is no direct bus from Port Orange to Lake City station. However, there are services departing from Daytona Beach and arriving at Lake City Bus Station via Jacksonville. The journey, including transfers, takes approximately 3h 52m.
The distance between Port Orange and Lake City is 159 miles. The road distance is 136.3 miles.
The best way to get from Port Orange to Lake City without a car is to bus which takes 3h 52m and costs $45 - $70.
It takes approximately 3h 52m to get from Port Orange to Lake City, including transfers.
Port Orange to Lake City bus services, operated by Flixbus USA, depart from Daytona Beach station.
Port Orange to Lake City bus services, operated by Flixbus USA, arrive at Jacksonville station.
Yes, the driving distance between Port Orange to Lake City is 136 miles. It takes approximately 2h 48m to drive from Port Orange to Lake City.
Book your Port Orange to Lake City bus tickets online with Omio.
What companies run services between Port Orange, FL, USA and Lake City, FL, USA?
You can take a vehicle from Port Orange to Lake City Bus Station via Daytona Beach and Jacksonville in around 3h 52m.
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Daytona Beach to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- 4 times a day
- Estimated price
- $13–20
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Jacksonville to Lake City Bus Station
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $9–16
- Website
- Greyhound
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There are 28+ hotels available in Lake City.