There are 7 ways to get from Syracuse to Lexington by plane, car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Syracuse Hancock International Airport to Covington, drive
best- Fly from Syracuse Hancock International Airport (SYR) to Covington (CVG)plane SYR - CVG
- Drive from Covington (CVG) to Lexingtoncar
7h 12m$176–973Fly Syracuse Hancock International Airport to Blue Grass Airport
cheapest- Fly from Syracuse Hancock International Airport (SYR) to Blue Grass Airport (LEX)plane SYR - LEX
7h 47m$103–603Train, bus, drive (Amtrak)
- Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain
- Take the bus from Chicago Union Station to Louisville, KYbus
- Drive from Middletown Station @ Target to Lexingtoncar
25h 21m$433–650Drive 663.6 mi
- Drive from Syracuse to Lexingtoncar 663.6 mi
11h 22m$122–175Fly Syracuse Hancock International Airport to Louisville International Airport, drive
- Fly from Syracuse Hancock International Airport (SYR) to Louisville International Airport (SDF)plane SYR - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
7h 14m$195–1,022Train to Rochester, fly to Blue Grass Airport
- Take the train from Syracuse Regional Transportation Center to Rochestertrain
- Fly from Rochester (ROC) to Blue Grass Airport (LEX)plane ROC - LEX
8h 38m$137–732Bus to Greater Binghamton Airport, fly to Blue Grass Airport
- Take the bus from Syracuse to Binghamtonbus
- Fly from Greater Binghamton Airport (BGM) to Blue Grass Airport (LEX)plane BGM - LEX
11h 54m$118–456
Syracuse Hancock International Airport (SYR) to Covington (CVG) flights
Comparing Your Travel Options
The cheapest way to get from Syracuse to Lexington is to drive which costs $120 - $180 and takes 11h 22m.
The fastest way to get from Syracuse to Lexington is to fly and drive which takes 7h 12m and costs $170 - $1,000.
The distance between Syracuse and Lexington is 626 miles. The road distance is 667.5 miles.
It takes approximately 7h 12m to get from Syracuse to Lexington, including transfers.
Yes, the driving distance between Syracuse to Lexington is 667 miles. It takes approximately 11h 22m to drive from Syracuse to Lexington.
There are 181+ hotels available in Lexington.
What companies run services between Syracuse, NY, USA and Lexington, KY, USA?
Delta and American Airlines fly from Syracuse Hancock International Airport (SYR) to Blue Grass Airport (LEX) every 3 hours.
- Website
- delta.com
Flights from Syracuse Hancock International Airport to Covington via Detroit
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $160–950
Flights from Syracuse Hancock International Airport to Covington via New York La Guardia
- Ave. Duration
- 6h 3m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $190–1,000
Flights from Syracuse Hancock International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $180–1,000
Flights from Syracuse Hancock International Airport to Louisville International Airport via New York La Guardia
- Ave. Duration
- 4h 54m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $210–1,100
Flights from Syracuse Hancock International Airport to Blue Grass Airport via Detroit
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $100–600
Flights from Syracuse Hancock International Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $140–700
Flights from Syracuse Hancock International Airport to Blue Grass Airport via New York La Guardia
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $110–650
Flights from Rochester to Blue Grass Airport via Detroit
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $95–550
Flights from Rochester to Blue Grass Airport via Atlanta
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $130–700
Flights from Rochester to Blue Grass Airport via New York La Guardia
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $110–650
Flights from Greater Binghamton Airport to Blue Grass Airport via Detroit
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- $70–390
Flights from Greater Binghamton Airport to Blue Grass Airport via Detroit, Atlanta
- Ave. Duration
- 8h 32m
- When
- Every day
- Estimated price
- $100–550
Flights from Greater Binghamton Airport to Blue Grass Airport via Detroit, Reagan Washington
- Ave. Duration
- 8h 39m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–490
- Website
- aa.com
Flights from Syracuse Hancock International Airport to Covington via Philadelphia
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $180–1,000
Flights from Syracuse Hancock International Airport to Covington via Reagan Washington
- Ave. Duration
- 4h 39m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–1,000
Flights from Syracuse Hancock International Airport to Louisville International Airport via Reagan Washington
- Ave. Duration
- 5h 2m
- When
- Sunday, Monday, Tuesday, Wednesday, Thursday, and Friday
- Estimated price
- $190–1,100
Flights from Syracuse Hancock International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Syracuse Hancock International Airport to Louisville International Airport via Philadelphia
- Ave. Duration
- 6h 9m
- When
- Every day
- Estimated price
- $200–1,100
Flights from Syracuse Hancock International Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 5h 53m
- When
- Every day
- Estimated price
- $120–650
Flights from Syracuse Hancock International Airport to Blue Grass Airport via Philadelphia
- Ave. Duration
- 6h 47m
- When
- Every day
- Estimated price
- $110–600
Flights from Rochester to Blue Grass Airport via Charlotte
- Ave. Duration
- 5h 21m
- When
- Every day
- Estimated price
- $110–650
Flights from Rochester to Blue Grass Airport via Philadelphia
- Ave. Duration
- 6h 40m
- When
- Every day
- Estimated price
- $110–600
Flights from Rochester to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 21m
- When
- Every day
- Estimated price
- $110–650
- Website
- united.com
Flights from Syracuse Hancock International Airport to Covington via Washington Dulles
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $170–1,000
Flights from Syracuse Hancock International Airport to Louisville International Airport via Washington Dulles
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $190–1,100
Flights from Rochester to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 51m
- When
- Every day
- Estimated price
- $110–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Chicago Union Station
- Ave. Duration
- 13h 7m
- Frequency
- Twice daily
- Estimated price
- $360–600
- Website
- Amtrak
Train from Syracuse Regional Transportation Center to Rochester
- Ave. Duration
- 1h 16m
- Frequency
- 5 times a day
- Estimated price
- $40–70
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Syracuse Regional Transportation Center to Rochester
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- $21–160
- Website
- VIA Rail
- Escape
- $21–70
- Business
- $50–150
- Business Plus
- $60–160
- Economy
- $23–80
- Economy Plus
- $26–85
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Chicago Union Station to Louisville, KY
- Ave. Duration
- 6h 45m
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- Amtrak
- Adult
- $50–60
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Syracuse to Binghamton
- Ave. Duration
- 1h 15m
- Frequency
- 5 times a day
- Estimated price
- $12–20
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Syracuse to Binghamton
- Ave. Duration
- 1h 30m
- Frequency
- 4 times a day
- Estimated price
- $11–18
- Schedules at
- Flixbus USA
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