There are 5 ways to get from Sarasota to Santee by plane, car, bus (Flixbus), bus, train, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Sarasota–Bradenton International Airport to Columbia, drive
best- Fly from Sarasota–Bradenton International Airport (SRQ) to Columbia (CAE)plane SRQ - CAE
- Drive from Columbia-Airport-CAE to Santeecar
6h$110–618Drive 479.2 mi
cheapest- Drive from Sarasota to Santeecar 479.2 mi
8h 15m$88–127Bus (Flixbus)
- Take the bus from Sarasota Cattlemen Transfer Center to Orlando Bus Stationbus FlixBus 2421
- Take the bus from Orlando Bus Station to Orangeburgbus FlixBus 2433
13h 31m$158–226Bus, train, taxi (Amtrak)
- Take the bus from Sarasota Amtrak Bus Stop to Tampabus
- Take the train from Tampa to Denmark Amtrak Stationtrain
- Take the taxi from Denmark Amtrak Station to Santeetaxi
15h 9mBus to Tampa, fly to Charleston International Airport, drive
- Take the bus from Sarasota Cattlemen Transfer Center to Tampa Bus Stationbus
- Fly from Tampa (TPA) to Charleston International Airport (CHS)plane TPA - CHS
- Drive from Charleston-Airport-CHS to Santeecar
7h 27m$102–496
Sarasota–Bradenton International Airport (SRQ) to Columbia (CAE) flights
Comparing Your Travel Options
The cheapest way to get from Sarasota to Santee is to drive which costs $85 - $130 and takes 8h 15m.
The fastest way to get from Sarasota to Santee is to fly and drive which takes 6h and costs $110 - $650.
No, there is no direct bus from Sarasota to Santee. However, there are services departing from Fruitville Rd @ N Lime Ave and arriving at Orangeburg via Sarasota Cattlemen Transfer Center and Orlando Bus Station. The journey, including transfers, takes approximately 13h 31m.
The distance between Sarasota and Santee is 529 miles. The road distance is 482 miles.
The best way to get from Sarasota to Santee without a car is to bus which takes 13h 31m and costs $150 - $230.
It takes approximately 6h to get from Sarasota to Santee, including transfers.
Sarasota to Santee bus services, operated by Flixbus USA, depart from Sarasota Cattlemen Transfer Center station.
Sarasota to Santee bus services, operated by Flixbus USA, arrive at Orlando Bus Station.
Yes, the driving distance between Sarasota to Santee is 482 miles. It takes approximately 8h 15m to drive from Sarasota to Santee.
There are 40+ hotels available in Santee.
What companies run services between Sarasota, FL, USA and Santee, SC, USA?
You can take a bus from Fruitville Rd @ N Lime Ave to Santee via Cattlemen Transit Station, Sarasota Cattlemen Transfer Center, Orlando Bus Station, and Orangeburg in around 13h 31m.
- Website
- delta.com
Flights from Sarasota–Bradenton International Airport to Columbia via Atlanta
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $100–600
Flights from Tampa to Charleston International Airport via Atlanta
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $80–460
- Website
- aa.com
Flights from Sarasota–Bradenton International Airport to Columbia via Charlotte
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $100–600
Flights from Sarasota–Bradenton International Airport to Columbia via Philadelphia
- Ave. Duration
- 5h 38m
- When
- Tuesday
- Estimated price
- $190–900
Flights from Sarasota–Bradenton International Airport to Columbia via Reagan Washington
- Ave. Duration
- 5h 52m
- When
- Saturday and Sunday
- Estimated price
- $160–800
- Website
- flybreeze.com
Flights from Tampa to Charleston International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $140–950
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Tampa to Denmark Amtrak Station
- Ave. Duration
- 10h 13m
- Frequency
- Once daily
- Estimated price
- $260–410
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Sarasota Cattlemen Transfer Center to Orlando Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Schedules at
- Flixbus USA
Bus from Orlando Bus Station to Orangeburg
- Ave. Duration
- 7h 20m
- Frequency
- Once daily
- Estimated price
- $55–90
- Schedules at
- Flixbus USA
Bus from Sarasota Cattlemen Transfer Center to Tampa Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Estimated price
- $9–15
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Sarasota Amtrak Bus Stop to Tampa
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Website
- Amtrak
- Ave. Duration
- 57 min
- Estimated price
- $140–180
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