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How to get fromMelbourne to Florida Keysby car, plane, taxi, bus, shuttle, or train

Find Transport to Florida Keys

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There are 9 ways to get from Melbourne to Florida Keys by car, plane, taxi, bus, shuttle, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Orlando Sanford, fly to Key West International Airport

    best
    1. Drive from Melbourne to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    5h 41m
    $125–373

  2. Drive  316.5 mi

    cheapest
    1. Drive from Melbourne to Florida Keyscar car 316.5 mi
    6h 2m
    $58–84

  3. Taxi, bus via Fort Pierce South

    1. Take the taxi from Melbourne to Sebastiantaxi taxi
    2. Take the bus from Sebastian to Fort Piercebus bus
    3. Take the bus from Fort Pierce to Miami Airportbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    10h 40m
    $143–194

  4. Shuttle, bus

    1. Take a shuttle bus from Melbourne, FL - Mobil Gas to Orlando Airportshuttle bus
    2. Take the bus from Orlando to Fort Lauderdale International Airportbus bus
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus
    13h 53m
    $260–322

  5. Line 20 bus, shuttle to Orlando, fly to Key West International Airport, bus

    1. Take the bus from Melbourne Square Mall to West New Haven Ave @ Goodwillbus bus
    2. Take a shuttle bus from Melbourne, FL - Mobil Gas to Orlando Airportshuttle bus
    3. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    4. Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus bus
    7h 52m
    $198–810

  6. Taxi, bus, bus to Miami International Airport, fly to Key West International Airport

    1. Take the taxi from Melbourne to Sebastiantaxi taxi
    2. Take the bus from Sebastian to Fort Piercebus bus
    3. Take the bus from Fort Pierce to Miami Airportbus bus
    4. Fly from Miami International Airport (MIA) to Key West International Airport (EYW)plane plane MIA - EYW
    9h 13m
    $227–469

  7. Shuttle to Orlando, fly to Miami International Airport, shuttle

    1. Take a shuttle bus from Melbourne, FL - Mobil Gas to Orlando Airportshuttle bus
    2. Fly from Orlando (MCO) to Miami International Airport (MIA)plane plane MCO - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 18m
    $808–1,350

  8. Drive, train, bus

    1. Drive from Melbourne to Orlandocar car
    2. Take the train from Orlando to Miamitrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    11h 28m
    $76–228

  9. Taxi, bus

    1. Take the taxi from Melbourne to Sebastiantaxi taxi
    2. Take the bus from Sebastian to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    11h 59m
    $135–186

Melbourne to Florida Keys by bus, shuttle, and foot

Calendar14Weekly Services
Duration13h 53mAverage Duration
Ticket$260Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Melbourne to Florida Keys.ExpandLaunch map view
  • Distance: 386.7 mi
  • Duration: 5h 41m

What companies run services between Melbourne, FL, USA and Florida Keys, FL, USA?

There is no direct connection from Melbourne to Florida Keys. However, you can drive to Orlando-Sanford-Airport-SFB airport, fly to Key West International Airport (EYW), walk to Key West Airport, take the shuttle to Key West, FL, walk to Whitehead & Eaton, take the bus to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, then walk to Florida Keys. Alternatively, you can take the taxi to Sebastian, take the bus to Fort Pierce, take the bus to Miami Airport, walk to Miami International Airport, take the vehicle to Miami Airport Station, walk to Miami, Airport Intermodal Station, take the bus to Big Pine Key, walk to Big Pine Key - CVS / MM30, take the bus to Sugarloaf Key - Lower - Sugarloaf Lodge, then walk to Florida Keys.

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