There are 5 ways to get from Manhattan to San Diego by plane, bus (Greyhound, Flixbus), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Manhattan Regional Airport
best- Fly from Manhattan Regional Airport (MHK) to San Diego International Airport (SAN)plane MHK - SAN
5h 59m$137–582Bus to Salina Municipal Airport, fly
cheapest- Take the bus from Manhattan KS to Salinabus
- Fly from Salina Municipal Airport (SLN) to San Diego International Airport (SAN)plane SLN - SAN
8h 15m$118–482Bus
- Take the bus from Manhattan KS to Denver Union Stationbus
- Take the bus from Denver Union Station to Las Vegas Bus Terminalbus
- Take the bus from Las Vegas Bus Terminal to Santa Ana Bus Stopbus
- Take the bus from Santa Ana Bus Stop to San Diegobus
34h 45m$256–420Drive, train (Amtrak)
- Drive from Manhattan to Topeka Stationcar
- Take the train from Topeka Station to Fullerton Amtrak Stationtrain
- Take the train from Fullerton Amtrak Station to San Diegotrain
37h 24m$965–1,605Drive 1,453.3 mi
- Drive from Manhattan to San Diegocar 1,453.3 mi
25h 14m$266–384
Manhattan to San Diego by bus
Comparing Your Travel Options
The cheapest way to get from Manhattan to San Diego is to bus and fly which costs $110 - $490 and takes 8h 15m.
The fastest way to get from Manhattan to San Diego is to fly which takes 5h 59m and costs $130 - $600.
No, there is no direct bus from Manhattan to San Diego. However, there are services departing from Manhattan KS and arriving at San Diego via Denver Union Station, Las Vegas Bus Terminal and Santa Ana Bus Stop. The journey, including transfers, takes approximately 34h 45m.
The distance between Manhattan and San Diego is 1242 miles. The road distance is 1461.8 miles.
The best way to get from Manhattan to San Diego without a car is to bus which takes 34h 45m and costs $250 - $420.
It takes approximately 5h 59m to get from Manhattan to San Diego, including transfers.
Manhattan to San Diego bus services, operated by Greyhound USA, depart from Manhattan KS station.
The best way to get from Manhattan to San Diego is to fly which takes 5h 59m and costs $130 - $600. Alternatively, you can bus, which costs $250 - $420 and takes 34h 45m.
Manhattan to San Diego bus services, operated by Greyhound USA, arrive at Denver Union Station.
San Diego is 2h behind Manhattan. It is currently 13:29 in Manhattan and 11:29 in San Diego.
What companies run services between Manhattan, KS, USA and San Diego, CA, USA?
American Airlines flies from Manhattan Regional Airport (MHK) to San Diego International Airport (SAN) 4 times a day. Alternatively, you can take a bus from Manhattan KS to San Diego via Denver Union Station, Las Vegas Bus Terminal, and Santa Ana Bus Stop in around 34h 45m.
- Website
- aa.com
Flights from Manhattan Regional Airport to San Diego International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- $110–550
Flights from Manhattan Regional Airport to San Diego International Airport via Chicago O'Hare
- Ave. Duration
- 7h 25m
- When
- Every day
- Estimated price
- $140–650
- Website
- united.com
Flights from Salina Municipal Airport to San Diego International Airport via Denver
- Ave. Duration
- 5h 51m
- When
- Every day
- Estimated price
- $95–450
Flights from Salina Municipal Airport to San Diego International Airport via Houston
- Ave. Duration
- 7h 17m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $130–600
Flights from Salina Municipal Airport to San Diego International Airport via Chicago O'Hare
- Ave. Duration
- 8h 33m
- When
- Every day
- Estimated price
- $150–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Topeka Station to Fullerton Amtrak Station
- Ave. Duration
- 33h 5m
- Frequency
- Once daily
- Estimated price
- $900–1,500
- Website
- Amtrak
Train from Fullerton Amtrak Station to San Diego
- Ave. Duration
- 2h 26m
- Frequency
- Hourly
- Estimated price
- $55–90
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Manhattan KS to Denver Union Station
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- $80–130
- Website
- Greyhound
Bus from Denver Union Station to Las Vegas Bus Terminal
- Ave. Duration
- 15h 30m
- Frequency
- Once daily
- Estimated price
- $120–200
- Website
- Greyhound
Bus from Las Vegas Bus Terminal to Santa Ana Bus Stop
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Estimated price
- $40–70
- Website
- Greyhound
Bus from Manhattan KS to Salina
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $11–19
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Santa Ana Bus Stop to San Diego
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $13–21
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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Read the travel guideBooking & Getting There
Yes, the driving distance between Manhattan to San Diego is 1462 miles. It takes approximately 25h 14m to drive from Manhattan to San Diego.
Book your Manhattan to San Diego bus tickets online with Omio and FlixBus.
There are 2375+ hotels available in San Diego.