There are 3 ways to get from Mayo Clinic Florida to Orlando by train (Amtrak), bus (Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Jacksonville to Orlandotrain Floridian / ...
3h 37m$142–203Drive 137.2 mi
cheapest- Drive from Mayo Clinic Florida to Orlandocar 137.2 mi
2h 19m$25–37Bus
- Take the bus from Beach Blvd + Suni Pines Blvd to JRTC Bay Mbus Fcf
- Take the bus from Jacksonville to Orlando Bus Stationbus FlixBus 2433 / ...
4h 40m$30–47
Comparing Your Travel Options
The cheapest way to get from Mayo Clinic Florida to Orlando is to drive which costs $25 - $40 and takes 2h 19m.
The fastest way to get from Mayo Clinic Florida to Orlando is to drive which takes 2h 19m and costs $25 - $40.
No, there is no direct bus from Mayo Clinic Florida to Orlando station. However, there are services departing from Beach Blvd + Suni Pines Blvd and arriving at Orlando Bus Station via Jacksonville. The journey, including transfers, takes approximately 4h 40m.
No, there is no direct train from Mayo Clinic Florida to Orlando. However, there are services departing from Jacksonville and arriving at Orlando via . The journey, including transfers, takes approximately 3h 37m.
The distance between Mayo Clinic Florida and Orlando is 172 miles. The road distance is 138 miles.
The best way to get from Mayo Clinic Florida to Orlando without a car is to train which takes 3h 37m and costs $140 - $210.
It takes approximately 3h 37m to get from Mayo Clinic Florida to Orlando, including transfers.
Mayo Clinic Florida to Orlando bus services, operated by Jacksonville Transport, depart from Beach Blvd + Suni Pines Blvd station.
Mayo Clinic Florida to Orlando train services, operated by Amtrak, depart from Jacksonville station.
The best way to get from Mayo Clinic Florida to Orlando is to train which takes 3h 37m and costs $140 - $210. Alternatively, you can bus, which costs $29 - $50 and takes 4h 40m.
What companies run services between Mayo Clinic Florida, FL, USA and Orlando, FL, USA?
Amtrak operates a train from Jacksonville to Orlando twice daily. Tickets cost $80–130 and the journey takes 3h 7m. Alternatively, you can take a vehicle from Mayo Clinic Florida to Orlando Bus Station via Beach Blvd + Suni Pines Blvd, JRTC Bay M, and Jacksonville in around 4h 40m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Jacksonville to Orlando
- Ave. Duration
- 3h 7m
- Frequency
- Twice daily
- Estimated price
- $80–130
- Website
- Amtrak
- Phone
- +1 904-630-3100
- Website
- Jacksonville Transport
Bus from Beach Blvd + Suni Pines Blvd to JRTC Bay M
- Ave. Duration
- 1h 1m
- Frequency
- Every 30 minutes
- Estimated price
- $1–3
- Website
- Jacksonville Transport
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Jacksonville to Orlando Bus Station
- Ave. Duration
- 2h 35m
- Frequency
- Every 4 hours
- Estimated price
- $21–35
- Schedules at
- Flixbus USA
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Mayo Clinic Florida to Orlando bus services, operated by Jacksonville Transport, arrive at JRTC Bay M station.
Mayo Clinic Florida to Orlando train services, operated by Amtrak, arrive at Orlando station.
Yes, the driving distance between Mayo Clinic Florida to Orlando is 138 miles. It takes approximately 2h 19m to drive from Mayo Clinic Florida to Orlando.
There are 1991+ hotels available in Orlando.