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How to get fromOttumwa to Louisvilleby bus (Greyhound, Amtrak), train, bus, car, plane, or taxi

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There are 9 ways to get from Ottumwa to Louisville by bus (Greyhound, Amtrak), train, bus, car, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Ottumwa Bus Stop to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    10h 25m
    $84–140

  2. Train, bus via Chicago (Amtrak)

    1. Take the train from Ottumwa Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    14h 21m
    $276–452

  3. Drive  488.6 mi

    1. Drive from Ottumwa to Louisvillecar car 488.6 mi
    8h 33m
    $90–129

  4. Bus to Des Moines, fly to Louisville International Airport

    1. Take the bus from Ottumwa Bus Stop to Des Moinesbus bus
    2. Fly from Des Moines (DSM) to Louisville International Airport (SDF)plane plane DSM - SDF
    8h 41m
    $232–1,186

  5. Train, bus

    1. Take the train from Ottumwa Amtrak Station to Galesburg Amtrak Stationtrain train
    2. Take the bus from Galesburg to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    11h 16m
    $127–209

  6. Train, taxi to Quad City International Airport, fly to Louisville International Airport

    1. Take the train from Ottumwa Amtrak Station to Galesburg Amtrak Stationtrain train
    2. Take the taxi from Galesburg Amtrak Station to SouthPark Mall Sheltertaxi taxi
    3. Fly from Quad City International Airport (MLI) to Louisville International Airport (SDF)plane plane MLI - SDF
    10h 8m
    $282–853

  7. Train to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the train from Ottumwa Amtrak Station to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    9h 53m
    $252–895

  8. Drive to Burlington Municipal Airport, fly to Louisville International Airport

    1. Drive from Ottumwa to Burlington Municipal Airport (BRL)car car
    2. Fly from Burlington Municipal Airport (BRL) to Louisville International Airport (SDF)plane plane BRL - SDF
    7h 35m
    $115–623

  9. Bus to Des Moines, fly to Nashville, bus

    1. Take the bus from Ottumwa Bus Stop to Des Moinesbus bus
    2. Fly from Des Moines (DSM) to Nashville (BNA)plane plane DSM - BNA
    3. Take the bus from Nashville to Louisville, KYbus bus
    10h 52m
    $203–935

Ottumwa to Louisville by bus

Calendar7Weekly Buses
Duration10h 25mAverage Duration
Ticket$84Cheapest Price
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Comparing Your Travel Options

Map of how to get from Ottumwa to Louisville.ExpandLaunch map view
  • Distance: 490.1 mi
  • Duration: 10h 25m

What companies run services between Ottumwa, IA, USA and Louisville, KY, USA?

You can take a bus from Ottumwa Bus Stop to Louisville, KY via Indianapolis Union Station in around 10h 25m.

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