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How to get fromOrlando to Spartanburgby plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or bus (Greyhound)

Find Transport to Spartanburg

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There are 8 ways to get from Orlando to Spartanburg by plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Orlando to Greenville–Spartanburg International Airport

    best
    1. Fly from Orlando (MCO) to Greenville–Spartanburg International Airport (GSP)plane plane MCO - GSP
    3h 22m
    $147–622

  2. Drive  517 mi

    cheapest
    1. Drive from Orlando to Spartanburgcar car 517 mi
    8h 32m
    $95–137

  3. Bus

    1. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus FlixBus 2433
    2. Take the bus from Charlotte Bus Station to Spartanburgbus bus Greyhound US0670
    12h 30m
    $104–154

  4. Train (Amtrak)

    1. Take the train from Orlando to Carytrain train
    2. Take the train from Cary to Charlotte Amtrak Stationtrain train
    3. Take the train from Charlotte Amtrak Station to Spartanburg Stationtrain train
    19h 58m
    $478–738

  5. Fly Orlando Sanford to Asheville Regional Airport, drive

    1. Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane plane SFB - AVL
    2. Drive from Asheville-Airport-AVL to Spartanburgcar car
    3h 8m
    $125–438

  6. Fly Orlando Sanford to Greenville–Spartanburg International Airport

    1. Fly from Orlando Sanford (SFB) to Greenville–Spartanburg International Airport (GSP)plane plane SFB - GSP
    2h 26m
    $196–693

  7. Bus to Tampa, fly to Greenville–Spartanburg International Airport

    1. Take the bus from Orlando Bus Station to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Greenville–Spartanburg International Airport (GSP)plane plane TPA - GSP
    5h 45m
    $135–305

  8. Bus via Atlanta (Greyhound)

    1. Take the bus from Orlando Bus Station to Gainesville Bus Stopbus bus
    2. Take the bus from Gainesville Bus Stop to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Spartanburgbus bus
    15h 5m
    $118–185

Orlando to Spartanburg by train (Amtrak)

Calendar7Weekly Trains
Duration19h 58mAverage Duration
Ticket$478Cheapest Price
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Comparing Your Travel Options

Map of how to get from Orlando to Spartanburg.ExpandLaunch map view
  • Distance: 485 mi
  • Duration: 3h 22m

What companies run services between Orlando, FL, USA and Spartanburg, SC, USA?

Breeze Airways, Delta, and American Airlines fly from Orlando (MCO) to Greenville–Spartanburg International Airport (GSP) every 2 hours. Alternatively, you can take a bus from Orlando Bus Station to Spartanburg via Charlotte Bus Station and Spartanburg in around 12h 30m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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