There are 2 ways to get from Orlando to Lake City by bus (Greyhound) or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Orlando to Lake City by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Orlando to Lake City is to bus which costs $25 - $40 and takes 3h 45m.
The fastest way to get from Orlando to Lake City is to drive which takes 2h 30m and costs $28 - $45.
Yes, there is a direct bus departing from Orlando Bus Station station and arriving at Lake City Bus Station station. Services depart once daily, and operate every day. The journey takes approximately 3h 45m.
The distance between Orlando and Lake City is 156 miles. The road distance is 154.2 miles.
The best way to get from Orlando to Lake City without a car is to bus which takes 3h 45m and costs $25 - $40.
The bus from Orlando Bus Station to Lake City Bus Station takes 3h 45m including transfers and departs once daily.
Orlando to Lake City bus services, operated by Greyhound USA, depart from Orlando Bus Station.
Orlando to Lake City bus services, operated by Greyhound USA, arrive at Lake City Bus Station.
Yes, the driving distance between Orlando to Lake City is 154 miles. It takes approximately 2h 30m to drive from Orlando to Lake City.
Book your Orlando to Lake City bus tickets online with Omio and FlixBus.
What companies run services between Orlando, FL, USA and Lake City, FL, USA?
Greyhound USA operates a bus from Orlando Bus Station to Lake City Bus Station once daily. Tickets cost $25–40 and the journey takes 3h 45m.
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Orlando Bus Station to Lake City Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $25–40
- Website
- Greyhound
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There are 28+ hotels available in Lake City.