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How to get fromOhio to Iowaby plane, bus (Greyhound), car, bus, bus (Flixbus, Greyhound), or train

Find Transport to Iowa

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There are 10 ways to get from Ohio to Iowa by plane, bus (Greyhound), car, bus, bus (Flixbus, Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Glenn Columbus International Airport to Des Moines

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Des Moines (DSM)plane plane CMH - DSM
    5h 28m
    $100–506

  2. Fly John Glenn Columbus International Airport to Quad City International Airport

    cheapest
    1. Fly from John Glenn Columbus International Airport (CMH) to Quad City International Airport (MLI)plane plane CMH - MLI
    7h 2m
    $74–445

  3. Bus (Greyhound)

    1. Take the bus from Columbus to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    15h 5m
    $113–176

  4. Drive  620.1 mi

    1. Drive from Columbus to Des Moinescar car 620.1 mi
    11h 27m
    $114–164

  5. Fly John Glenn Columbus International Airport to Omaha

    1. Fly from John Glenn Columbus International Airport (CMH) to Omaha (OMA)plane plane CMH - OMA
    5h 37m
    $677–1,533

  6. Bus to Detroit, fly to Des Moines

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Des Moines (DSM)plane plane DTW - DSM
    5h 22m

  7. Bus to Detroit, fly to Omaha

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Omaha (OMA)plane plane DTW - OMA
    5h 42m

  8. Fly Covington to Quad City International Airport

    1. Fly from Covington (CVG) to Quad City International Airport (MLI)plane plane CVG - MLI
    7h 30m
    $86–496

  9. Bus #2

    1. Take the bus from Columbus to Chicago Bus Stationbus bus FlixBus 2511 / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    15h 5m
    $117–176

  10. Bus, train

    1. Take the bus from Columbus to Toledobus bus
    2. Take the train from Toledo to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    17h 54m
    $267–441

John Glenn Columbus International Airport (CMH) to Des Moines (DSM) flights

Calendar114Weekly Planes
Duration4h 34mAverage Duration
Ticket$84Cheapest Price
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Comparing Your Travel Options

Map of how to get from Ohio to Iowa.ExpandLaunch map view
  • Distance: 591.9 mi
  • Duration: 5h 28m

What companies run services between Ohio, USA and Iowa, USA?

Southwest Airlines, Delta, and two other airlines fly from John Glenn Columbus International Airport (CMH) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Columbus to Des Moines via Indianapolis Union Station and Des Moines in around 15h 5m.

Airlines
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Bus operators

Want to know more about travelling around United States

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Need to know: Greyhound

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