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How to get fromIsesaki to Osakaby train, bus, night bus, car, or plane

Find Transport to Osaka

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There are 11 ways to get from Isesaki to Osaka by train, bus, night bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from 高崎 Takasaki to Tōkyō Stationtrain train Ju / ...
    2. Take the train from Tōkyō Station to Kyototrain train Hikari / ...
    6h 10m

  2. Night bus

    cheapest
    1. Take the nightbus from Takasaki Station East to Osaka-Umedanightbus night bus Jx242 / ...
    10h 40m
    ¥5,921–11,566

  3. Bus

    1. Take the bus from 伊勢崎駅南口 to 大阪ocatbus bus 高速バス シルクライナー(太田経由)
    12h 30m
    ¥6,000–11,000

  4. Drive  479.3 km

    1. Drive from Isesaki to Osakacar car 479.3 km
    7h 21m
    ¥8,248–11,914

  5. Train via Odawara

    1. Take the train from Honjō to Odawaratrain train Takasakisen / ...
    2. Take the train from Odawara to Kyototrain train Kodama
    8h 37m

  6. Train to Tokyo International Airport, fly to Osaka International Airport

    1. Take the train from Ota(Gunma) to Kita-Senjutrain train
    2. Fly from Tokyo International Airport (HND) to Osaka International Airport (ITM)plane plane HND - ITM
    6h 10m

  7. Train to Tokyo International Airport, fly to Kobe

    1. Take the train from Ota(Gunma) to Kita-Senjutrain train
    2. Fly from Tokyo International Airport (HND) to Kobe (UKB)plane plane HND - UKB
    6h 28m

  8. Train, train to Narita International Airport, fly to Osaka International Airport

    1. Take the train from Ota(Gunma) to Kita-Senjutrain train
    2. Take the train from Nippori to Narita Airport Terminal 2·3train train
    3. Fly from Narita International Airport (NRT) to Osaka International Airport (ITM)plane plane NRT - ITM
    6h 9m

  9. Train, train to Fukushima, fly to Osaka International Airport

    1. Take the train from Isesaki to Oyamatrain train
    2. Take the train from Oyama to Shin-Shirakawatrain train
    3. Fly from Fukushima (FKS) to Osaka International Airport (ITM)plane plane FKS - ITM
    6h 30m
    ¥21,963–43,061

  10. Train, train to Ibaraki Airport, fly to Kobe

    1. Take the train from Ota(Gunma) to Kita-Senjutrain train
    2. Take the train from Kita-Senju to Takahamatrain train
    3. Fly from Ibaraki Airport (IBR) to Kobe (UKB)plane plane IBR - UKB
    6h 58m

  11. Train, train to Matsumoto Airport, fly to Kobe

    1. Take the train from Takasaki to Naganotrain train
    2. Take the train from Nagano to Muraitrain train
    3. Fly from Matsumoto Airport (MMJ) to Kobe (UKB)plane plane MMJ - UKB
    7h 20m
    ¥18,591–37,626

Tokyo International Airport (HND) to Osaka International Airport (ITM) flights

Calendar224Weekly Planes
Duration1h 13mAverage Duration
Ticket¥11,988Cheapest Price
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Comparing Your Travel Options

Map of how to get from Isesaki to Osaka.ExpandLaunch map view
  • Distance: 643.4 km
  • Duration: 6h 10m

What companies run services between Isesaki, Japan and Osaka, Japan?

You can take a train from 伊勢崎 Isesaki to Shin-Ōsaka Station via 高崎 Takasaki, Tōkyō Station, Kyoto, and Kyōto in around 6h 10m. Alternatively, Nippon Chuo Bus operates a bus from 伊勢崎駅南口 to 大阪ocat once daily. Tickets cost ¥6,000–11,000 and the journey takes 12h 30m.

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