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How to get fromIllinois to Greenvilleby plane, bus (Greyhound), train, bus, car, taxi, bus (Greyhound, Flixbus), or bus (Flixbus, Greyhound)

Find Transport to Greenville

See all options

There are 7 ways to get from Illinois to Greenville by plane, bus (Greyhound), train, bus, car, taxi, bus (Greyhound, Flixbus), or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Greenville–Spartanburg International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)plane plane ORD - GSP
    4h 2m
    $118–530
  2. Bus

    1. Take the bus from Chicago Train Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus Charlotte
    21h 12m
    $166–254
  3. Train, bus

    1. Take the train from Chicago Union Station to Carytrain train
    2. Take the train from Cary to Charlotte Amtrak Stationtrain train
    3. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    32h 27m
    $725–1,121
  4. Drive  667.5 mi

    1. Drive from Chicago to Greenvillecar car 667.5 mi
    12h 43m
    $122–176
  5. Fly to Asheville Regional Airport, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    2. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    4h 37m
    $192–485
  6. Bus via Atlanta

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus Charlotte
    21h 38m
    $158–257
  7. Bus via Chicago

    1. Take the bus from Chicago to Atlanta Bus Stationbus bus FlixBus 2512
    2. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus Charlotte
    21h 51m
    $160–267

Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP) flights

Calendar70Weekly Planes
Duration3h 5mAverage Duration
Ticket$84Cheapest Price
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Comparing Your Travel Options

What companies run services between Illinois, USA and Greenville, SC, USA?

American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP) every 3 hours. Alternatively, you can take a bus from Chicago Train Station to Greenville via Atlanta Bus Station, Garnett Station, Doraville Station, Atlanta, and Taqueria Guadalajara - Greenville in around 21h 12m.

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Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There