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How to get fromIowa to Saint Charlesby plane, bus (Greyhound), bus, train, car, or taxi

Find Transport to Saint Charles

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There are 5 ways to get from Iowa to Saint Charles by plane, bus (Greyhound), bus, train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane plane DSM - STL
    5h 8m
    $159–797

  2. Drive  310.1 mi

    cheapest
    1. Drive from Des Moines to Saint Charlescar car 310.1 mi
    6h 19m
    $57–82

  3. Bus

    1. Take the bus from Des Moines to Kansas Citybus bus Jefferson Lines 803 / ...
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus Greyhound US0180s / ...
    10h 4m
    $113–161

  4. Bus, train

    1. Take the bus from Des Moines to Kansas Citybus bus Jefferson Lines 803 / ...
    2. Take the train from Kansas City to St. Louistrain train Missouri River Runner / ...
    12h 24m
    $223–336

  5. Line 41 bus to Omaha, fly, line 34 bus, taxi

    1. Take the bus from 1st Ave & 8th St NE to 11th & Dodge NEbus bus
    2. Fly from Omaha (OMA) to Lambert–St. Louis International Airport (STL)plane plane OMA - STL
    3. Take the bus from North Hanley Transit Center to 4375 Rider Trail North Sbbus bus
    4. Take the taxi from 4375 Rider Trail North Sb to Saint Charlestaxi taxi
    5h 11m
    $623–927

Des Moines (DSM) to Lambert–St. Louis International Airport (STL) flights

Calendar134Weekly Planes
Duration5h 11mAverage Duration
Ticket$126Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Iowa to Saint Charles.ExpandLaunch map view
  • Distance: 285.6 mi
  • Duration: 5h 8m

What companies run services between Iowa, USA and Saint Charles, MO, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a bus from Des Moines to Saint Charles via Kansas City, Kansas City Bus Station, St Louis Bus Station, CIVIC CENTER station, NORTH HANLEY station, North Hanley Transit Center, and 4375 Rider Trail North Sb in around 10h 4m.

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Want to know more about travelling around United States

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Need to know: Greyhound

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