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How to get fromIndianapolis to Isle of Palmsby plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or train

Find Transport to Isle of Palms

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There are 6 ways to get from Indianapolis to Isle of Palms by plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Indianapolis to Charleston International Airport

    best
    1. Fly from Indianapolis (IND) to Charleston International Airport (CHS)plane plane IND - CHS
    5h 58m
    $187–662

  2. Drive  700.9 mi

    cheapest
    1. Drive from Indianapolis to Isle of Palmscar car 700.9 mi
    12h 56m
    $128–185

  3. Bus

    1. Take the bus from Indianapolis to Atlanta Bus Stationbus bus FlixBus 2512
    2. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus Greyhound US0641S
    23h 49m
    $219–321

  4. Train (Amtrak)

    1. Take the train from Indianapolis to Alexandriatrain train Cardinal
    2. Take the train from Alexandria to Charleston Amtrak Stationtrain train Silver Meteor / ...
    28h 39m
    $723–1,098

  5. Bus to Covington, fly to Charleston International Airport

    1. Take the bus from Indianapolis to Cincinnatibus bus
    2. Fly from Covington (CVG) to Charleston International Airport (CHS)plane plane CVG - CHS
    6h 26m
    $209–790

  6. Fly Indianapolis to Savannah, train

    1. Fly from Indianapolis (IND) to Savannah (SAV)plane plane IND - SAV
    2. Take the train from Savannah Station to Charleston Amtrak Stationtrain train
    6h 46m
    $287–967

Indianapolis (IND) to Charleston International Airport (CHS) flights

Calendar112Weekly Planes
Duration4h 33mAverage Duration
Ticket$98Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Indianapolis to Isle of Palms.ExpandLaunch map view
  • Distance: 623.1 mi
  • Duration: 5h 58m

What companies run services between Indianapolis, IN, USA and Isle of Palms, SC, USA?

Southwest Airlines, Delta, and two other airlines fly from Indianapolis (IND) to Charleston International Airport (CHS) hourly. Alternatively, you can take a bus from Indianapolis to Isle of Palms via Atlanta Bus Station and Charleston Bus Station in around 23h 49m.

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Need to know: Greyhound

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